There are 10 ways to get from Minneapolis to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Charlotte  •  4 h 21 min

  1. Fly from Minneapolis (MSP) to Charlotte (CLT) MSP - CLT

$247 - $693

Cheapest option

Fly to Charleston  •  5 h 15 min

  1. Fly from Minneapolis (MSP) to Charleston (CHS) MSP - CHS

$164 - $706

8 alternative options

Fly to Florence  •  5 h 56 min

  1. Fly from Minneapolis (MSP) to Florence (FLO) MSP - FLO

$260 - $1,214

Fly to Greenville/Spartanburg  •  5 h 56 min

  1. Fly from Minneapolis (MSP) to Greenville/Spartanburg (GSP) MSP - GSP

$222 - $948

Fly to Columbia  •  5 h 59 min

  1. Fly from Minneapolis (MSP) to Columbia (CAE) MSP - CAE

$256 - $1,133

Bus via Savannah, Ga  •  34 h 17 min

  1. Take the bus from Minneapolis, Mn to Chicago, Il
  2. Take the bus from Chicago, Il to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to Savannah, Ga
  4. Take the bus from Savannah, Ga to Florence, Sc

$166 - $414

Bus  •  36 h 6 min

  1. Take the bus from Minneapolis, MN to Madison 965
  2. Take the bus from Madison, WI-Langdon & Park St to Chicago, IL - Amtrak
  3. Take the bus from Chicago to Marta Civic Center Station - Nb
  4. Take the bus from Atlanta, GA to Florence

$189 - $266

Train  •  36 h 21 min

  1. Take the train from St. Paul-Minneapolis Union Depot Amtrak to Chicago Union Station Amtrak
  2. Take the train from Chicago Union Station Amtrak to Washington Union Station Amtrak
  3. Take the train from Washington Union Station Amtrak to Florence Amtrak

$232 - $673

Train via Alexandria Amtrak  •  42 h 12 min

  1. Take the train from St. Paul-Minneapolis Union Depot Amtrak to Chicago Union Station Amtrak
  2. Take the train from Chicago Union Station Amtrak to Alexandria Amtrak
  3. Take the train from Alexandria Amtrak to Florence Amtrak

$247 - $703

Drive  •  21 h 35 min

  1. Drive from Minneapolis to Florence 1294.3 miles

$120 - $190

Questions & Answers

The cheapest way to get from Minneapolis to South Carolina is to drive which costs $120 - $190 and takes 21 h 35 min.

More details

The quickest way to get from Minneapolis to South Carolina is to fly which costs $240 - $700 and takes 4 h 21 min.

More details

The distance between Minneapolis and South Carolina is 1042 miles. The road distance is 1294.3 miles.

Get driving directions

It takes approximately 4 h 21 min to get from Minneapolis to South Carolina, including transfers.

More details

No, there is no direct bus from Minneapolis to South Carolina. However, there are services departing from Minneapolis, Mn and arriving at Florence, Sc via Chicago, Il, Atlanta, Ga and Savannah, Ga. The journey, including transfers, takes approximately 34 h 17 min.

More details

What companies run services between Minneapolis, MN, USA and South Carolina, USA?

Delta, American Airlines and two other airlines fly from Minneapolis to Rock Hill hourly. Alternatively, you can take a bus from Minneapolis to Florence via Chicago, Il, Atlanta, Ga, and Savannah, Ga in around 34 h 17 min.

Airlines
American Airlines
Website
aa.com
Flights from Minneapolis to Charlotte
Ave. Duration
2 h 35 min
When
Every day
Estimated price
$340 - $1,200
Flights from Minneapolis to Charlotte via Chicago O'Hare
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$340 - $1,200
Flights from Minneapolis to Florence via Charlotte
Ave. Duration
4 h 46 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,200
Flights from Minneapolis to Florence via Chicago O'Hare, Charlotte
Ave. Duration
6 h 59 min
When
Every day
Estimated price
$270 - $1,200
Flights from Minneapolis to Florence via Reagan Washington, Charlotte
Ave. Duration
8 h 47 min
When
Every day
Estimated price
$300 - $1,300
Flights from Minneapolis to Greenville/Spartanburg via Charlotte
Ave. Duration
5 h 2 min
When
Every day
Estimated price
$200 - $900
Flights from Minneapolis to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
4 h 56 min
When
Every day
Estimated price
$190 - $900
Flights from Minneapolis to Greenville/Spartanburg via Reagan Washington
Ave. Duration
6 h 9 min
When
Saturday
Estimated price
$220 - $950
Flights from Minneapolis to Columbia via Charlotte
Ave. Duration
5 h 5 min
When
Every day
Estimated price
$240 - $1,100
Flights from Minneapolis to Columbia via Philadelphia
Ave. Duration
6 h 33 min
When
Every day
Estimated price
$280 - $1,200
Flights from Minneapolis to Columbia via Reagan Washington
Ave. Duration
6 h 31 min
When
Every day
Estimated price
$270 - $1,200
Flights from Minneapolis to Columbia via Dallas/Ft.Worth
Ave. Duration
6 h 40 min
When
Every day
Estimated price
$310 - $1,200
Flights from Minneapolis to Charleston via Charlotte
Ave. Duration
4 h 49 min
When
Every day
Estimated price
$250 - $1,100
Delta
Website
delta.com
Flights from Minneapolis to Charlotte
Ave. Duration
2 h 35 min
When
Every day
Estimated price
$340 - $1,200
Flights from Minneapolis to Charlotte via Detroit
Ave. Duration
4 h 40 min
When
Saturday
Estimated price
$340 - $1,200
Flights from Minneapolis to Greenville/Spartanburg via Atlanta
Ave. Duration
5 h 12 min
When
Every day
Estimated price
$190 - $900
Flights from Minneapolis to Greenville/Spartanburg via Detroit
Ave. Duration
5 h 22 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $900
Flights from Minneapolis to Columbia via Atlanta
Ave. Duration
5 h 2 min
When
Every day
Estimated price
$230 - $1,100
Flights from Minneapolis to Columbia via New York La Guardia
Ave. Duration
7 h 18 min
When
Every day
Estimated price
$270 - $1,200
Flights from Minneapolis to Charleston via Atlanta
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$230 - $1,100
United Airlines
Website
united.com
Flights from Minneapolis to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
4 h 56 min
When
Every day
Estimated price
$200 - $950
Flights from Minneapolis to Greenville/Spartanburg via Washington Dulles
Ave. Duration
5 h 23 min
When
Every day
Estimated price
$230 - $1,000
Flights from Minneapolis to Greenville/Spartanburg via Newark
Ave. Duration
6 h 4 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,100
Flights from Minneapolis to Columbia via Chicago O'Hare
Ave. Duration
5 h 24 min
When
Every day
Estimated price
$250 - $1,200
Flights from Minneapolis to Columbia via Washington Dulles
Ave. Duration
5 h 29 min
When
Every day
Estimated price
$270 - $1,200
Flights from Minneapolis to Columbia via Houston
Ave. Duration
8 h 34 min
When
Saturday and Sunday
Estimated price
$320 - $1,400
Flights from Minneapolis to Charleston via Chicago O'Hare
Ave. Duration
4 h 53 min
When
Every day
Estimated price
$250 - $1,200
Southwest Airlines
Website
southwest.com
Flights from Minneapolis to Charlotte via Chicago Midway
Ave. Duration
4 h 10 min
When
Monday to Saturday
Estimated price
$330 - $1,700
Flights from Minneapolis to Greenville/Spartanburg via Atlanta
Ave. Duration
5 h 47 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $900
Flights from Minneapolis to Charleston via Chicago Midway
Ave. Duration
4 h 35 min
When
Monday to Saturday
Estimated price
$270 - $1,100
Flights from Minneapolis to Charleston via Nashville
Ave. Duration
4 h 35 min
When
Sunday
Estimated price
$280 - $1,100
Flights from Minneapolis to Charleston via St. Louis
Ave. Duration
4 h 35 min
When
Sunday
Estimated price
$280 - $1,100
Flights from Minneapolis to Charleston via Baltimore
Ave. Duration
4 h 45 min
When
Saturday
Estimated price
$310 - $1,200
Frontier Airlines
Website
flyfrontier.com
Flights from Minneapolis to Charleston
Ave. Duration
2 h 54 min
When
Wednesday and Saturday
Estimated price
$160 - $700
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from St. Paul-Minneapolis Union Depot Amtrak to Chicago Union Station Amtrak
Ave. Duration
7 h 55 min
Frequency
3 times a day
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Train from Chicago Union Station Amtrak to Washington Union Station Amtrak
Ave. Duration
17 h 25 min
Frequency
Once daily
Estimated price
$100 - $310
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$190 - $280
Business Coach Seat
$220 - $310
Room
$440 - $600
Train from Washington Union Station Amtrak to Florence Amtrak
Ave. Duration
7 h 40 min
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Train from Chicago Union Station Amtrak to Alexandria Amtrak
Ave. Duration
23 h 14 min
Frequency
4 times a week
Estimated price
$120 - $350
Website
amtrak.com
Coach Seat
$120 - $180
Flexi Coach Seat
$210 - $310
Business Coach Seat
$250 - $350
Room
$490 - $700
Train from Alexandria Amtrak to Florence Amtrak
Ave. Duration
7 h 21 min
Frequency
Twice daily
Estimated price
$60 - $170
Website
amtrak.com
Coach Seat
$60 - $95
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $170
Room
$280 - $390
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Minneapolis, Mn to Chicago, Il
Ave. Duration
8 h 35 min
Frequency
Hourly
Estimated price
$45 - $110
Website
greyhound.com
Economy
$45 - $75
Flexible
$85 - $110
Bus from Chicago, Il to Atlanta, Ga
Ave. Duration
15 h 45 min
Frequency
Every 3 hours
Estimated price
$70 - $180
Website
greyhound.com
Economy
$70 - $120
Flexible
$130 - $180
Bus from Atlanta, Ga to Savannah, Ga
Ave. Duration
4 h 35 min
Frequency
Every 30 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
Bus from Savannah, Ga to Florence, Sc
Ave. Duration
3 h 40 min
Frequency
Hourly
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Minneapolis, MN to Madison
Ave. Duration
6 h 25 min
Frequency
Every 3 hours
Estimated price
$55 - $85
Schedules at
jeffersonlines.com
Vangalder Bus
Phone
+1 608-752-5407
Email
vangalder@coachusa.com
Bus from Madison, WI-Langdon & Park St to Chicago, IL - Amtrak
Ave. Duration
3 h 15 min
Frequency
Hourly
Estimated price
$30
Schedules at
vangalderbus.com
Book at
govangalder.com
Megabus

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