There are 10 ways to get from Minneapolis to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Charlotte  •  4 h 24 min

  1. Fly from Minneapolis (MSP) to Charlotte (CLT) MSP - CLT

$247 - $693

Cheapest option

Bus via Columbia, SC  •  31 h 20 min

  1. Take the bus from Minneapolis, MN to Chicago
  2. Take the bus from Chicago to Marta Civic Center Station - Nb
  3. Take the bus from Atlanta GA to Columbia, SC
  4. Take the bus from Columbia, SC to Florence, SC

$137 - $205

8 alternative options

Fly to Greenville/Spartanburg  •  5 h 47 min

  1. Fly from Minneapolis (MSP) to Greenville/Spartanburg (GSP) MSP - GSP

$222 - $948

Fly to Columbia  •  5 h 54 min

  1. Fly from Minneapolis (MSP) to Columbia (CAE) MSP - CAE

$256 - $1,133

Fly to Florence  •  7 h 11 min

  1. Fly from Minneapolis (MSP) to Florence (FLO) MSP - FLO

$280 - $1,214

Fly to Charleston  •  6 h 45 min

  1. Fly from Minneapolis (MSP) to Charleston (CHS) MSP - CHS

$234 - $1,106

Bus  •  31 h 19 min

  1. Take the bus from Minneapolis, Mn to Chicago, Il
  2. Take the bus from Chicago, Il to Atlanta, Ga
  3. Take the bus from Atlanta, GA to Florence, SC

$153 - $352

Train  •  36 h 21 min

  1. Take the train from St. Paul-Minneapolis Union Depot to Chicago Union Station
  2. Take the train from Chicago Union Station to Washington Union Station
  3. Take the train from Washington Union Station to Florence Amtrak

$232 - $673

Train via Alexandria Amtrak  •  42 h 12 min

  1. Take the train from St. Paul-Minneapolis Union Depot to Chicago Union Station
  2. Take the train from Chicago Union Station to Alexandria Amtrak
  3. Take the train from Alexandria Amtrak to Florence Amtrak

$247 - $703

Drive  •  21 h 35 min

  1. Drive from Minneapolis to Florence 1294.3 miles

$120 - $190

Questions & Answers

No, there is no direct bus from Minneapolis to South Carolina. However, there are services departing from Minneapolis, Mn and arriving at Florence, SC via Chicago, Il, Peachtree St @ Alabama St and Atlanta, GA. The journey, including transfers, takes approximately 31 h 19 min.

More details

The distance between Minneapolis and South Carolina is 1042 miles. The road distance is 1294.3 miles.

Get driving directions

The best way to get from Minneapolis to South Carolina without a car is to bus which takes 31 h 19 min and costs .

More details

It takes approximately 4 h 24 min to get from Minneapolis to South Carolina, including transfers.

More details

Minneapolis to South Carolina bus services, operated by Greyhound USA, depart from Minneapolis, Mn station.

More details

The best way to get from Minneapolis to South Carolina is to fly which takes 4 h 24 min and costs . Alternatively, you can bus, which costs and takes 31 h 19 min, you could also train, which costs and takes 36 h 21 min.

Mode details

The quickest flight from Minneapolis Airport to Charlotte Airport is the direct flight which takes 2 h 33 min.

Search flights

Minneapolis to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

More details

South Carolina is 1 h ahead of Minneapolis. It is currently 6:31 AM in Minneapolis and 7:31 AM in South Carolina.

Yes, the driving distance between Minneapolis to South Carolina is 1294 miles. It takes approximately 21 h 35 min to drive from Minneapolis to South Carolina.

Get driving directions

Map of how to get from Minneapolis to South Carolina.
Launch map view
  • Distance: 1042.1 miles
  • Duration: 4 h 24 min

What companies run services between Minneapolis, MN, USA and South Carolina, USA?

Delta, American Airlines and two other airlines fly from Minneapolis to Rock Hill hourly. Alternatively, you can take a bus from Minneapolis to Florence via Chicago, Il, Atlanta, Ga, Peachtree St @ Alabama St, Peachtree St Sw @ Brotherton Transportation Mall, and Atlanta, GA in around 31 h 19 min.

Airlines
Delta
Website
delta.com
Flights from Minneapolis to Charlotte
Ave. Duration
2 h 36 min
When
Every day
Estimated price
$340 - $1,200
Flights from Minneapolis to Charlotte via Detroit
Ave. Duration
4 h 30 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$340 - $1,200
Flights from Minneapolis to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 55 min
When
Every day
Estimated price
$190 - $900
Flights from Minneapolis to Greenville/Spartanburg via Detroit
Ave. Duration
5 h 8 min
When
Every day
Estimated price
$190 - $900
Flights from Minneapolis to Greenville/Spartanburg via New York La Guardia
Ave. Duration
6 h 13 min
When
Monday, Thursday, Friday and Sunday
Estimated price
$230 - $1,000
Flights from Minneapolis to Columbia via Atlanta
Ave. Duration
5 h
When
Every day
Estimated price
$230 - $1,100
Flights from Minneapolis to Columbia via New York La Guardia
Ave. Duration
6 h 24 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,200
Flights from Minneapolis to Columbia via Rochester, Atlanta
Ave. Duration
5 h 54 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,100
Flights from Minneapolis to Charleston via Atlanta
Ave. Duration
5 h 8 min
When
Every day
Estimated price
$230 - $1,100
Flights from Minneapolis to Charleston via Detroit
Ave. Duration
5 h 14 min
When
Saturday
Estimated price
$240 - $1,100
American Airlines
Website
aa.com
Flights from Minneapolis to Charlotte
Ave. Duration
2 h 37 min
When
Every day
Estimated price
$340 - $1,200
Flights from Minneapolis to Charlotte via Chicago O'Hare
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$340 - $1,200
Flights from Minneapolis to Greenville/Spartanburg via Charlotte
Ave. Duration
5 h 16 min
When
Every day
Estimated price
$200 - $900
Flights from Minneapolis to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
5 h 10 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $900
Flights from Minneapolis to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
5 h 45 min
When
Every day
Estimated price
$250 - $1,000
Flights from Minneapolis to Greenville/Spartanburg via Reagan Washington
Ave. Duration
6 h 13 min
When
Saturday
Estimated price
$220 - $950
Flights from Minneapolis to Columbia via Charlotte
Ave. Duration
5 h 4 min
When
Every day
Estimated price
$240 - $1,100
Flights from Minneapolis to Columbia via Philadelphia
Ave. Duration
5 h 27 min
When
Every day
Estimated price
$280 - $1,200
Flights from Minneapolis to Columbia via Reagan Washington
Ave. Duration
6 h 29 min
When
Every day
Estimated price
$270 - $1,200
Flights from Minneapolis to Columbia via Dallas/Ft.Worth
Ave. Duration
6 h 49 min
When
Every day
Estimated price
$310 - $1,200
Flights from Minneapolis to Florence via Charlotte
Ave. Duration
7 h 43 min
When
Every day
Estimated price
$270 - $1,200
Flights from Minneapolis to Florence via Reagan Washington, Charlotte
Ave. Duration
8 h 9 min
When
Every day
Estimated price
$300 - $1,300
Flights from Minneapolis to Florence via Chicago O'Hare, Charlotte
Ave. Duration
8 h 32 min
When
Every day
Estimated price
$270 - $1,200
Flights from Minneapolis to Charleston via Chicago O'Hare
Ave. Duration
4 h 57 min
When
Monday, Wednesday, Thursday, Friday and Saturday
Estimated price
$250 - $1,100
Flights from Minneapolis to Charleston via Charlotte
Ave. Duration
5 h 19 min
When
Every day
Estimated price
$250 - $1,100
Flights from Minneapolis to Charleston via Reagan Washington
Ave. Duration
5 h 29 min
When
Every day
Estimated price
$270 - $1,200
United Airlines
Website
united.com
Flights from Minneapolis to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
5 h 2 min
When
Monday to Saturday
Estimated price
$200 - $950
Flights from Minneapolis to Greenville/Spartanburg via Washington Dulles
Ave. Duration
5 h 29 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,000
Flights from Minneapolis to Greenville/Spartanburg via Houston
Ave. Duration
6 h 9 min
When
Sunday
Estimated price
$270 - $1,200
Flights from Minneapolis to Columbia via Washington Dulles
Ave. Duration
5 h 14 min
When
Every day
Estimated price
$270 - $1,200
Flights from Minneapolis to Columbia via Chicago O'Hare
Ave. Duration
5 h 32 min
When
Every day
Estimated price
$250 - $1,200
Flights from Minneapolis to Columbia via Houston
Ave. Duration
8 h 39 min
When
Every day
Estimated price
$320 - $1,400
Flights from Minneapolis to Charleston via Chicago O'Hare
Ave. Duration
5 h 9 min
When
Every day
Estimated price
$250 - $1,200
Flights from Minneapolis to Charleston via Washington Dulles
Ave. Duration
5 h 24 min
When
Every day
Estimated price
$270 - $1,200
Southwest Airlines
Website
southwest.com
Flights from Minneapolis to Charlotte via Chicago Midway
Ave. Duration
4 h 10 min
When
Monday to Saturday
Estimated price
$330 - $1,700
Flights from Minneapolis to Greenville/Spartanburg via Atlanta
Ave. Duration
6 h 15 min
When
Sunday
Estimated price
$230 - $900
Flights from Minneapolis to Charleston via Chicago Midway
Ave. Duration
4 h 53 min
When
Every day
Estimated price
$270 - $1,100
Flights from Minneapolis to Charleston via Baltimore
Ave. Duration
5 h 15 min
When
Saturday
Estimated price
$310 - $1,200
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from St. Paul-Minneapolis Union Depot to Chicago Union Station
Ave. Duration
7 h 55 min
Frequency
3 times a day
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Train from Chicago Union Station to Washington Union Station
Ave. Duration
17 h 25 min
Frequency
Once daily
Estimated price
$100 - $310
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$190 - $280
Business Coach Seat
$220 - $310
Room
$440 - $600
Train from Washington Union Station to Florence Amtrak
Ave. Duration
7 h 40 min
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Train from Chicago Union Station to Alexandria Amtrak
Ave. Duration
23 h 14 min
Frequency
4 times a week
Estimated price
$120 - $350
Website
amtrak.com
Coach Seat
$120 - $180
Flexi Coach Seat
$210 - $310
Business Coach Seat
$250 - $350
Room
$490 - $700
Train from Alexandria Amtrak to Florence Amtrak
Ave. Duration
7 h 21 min
Frequency
Twice daily
Estimated price
$60 - $170
Website
amtrak.com
Coach Seat
$60 - $95
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $170
Room
$280 - $390
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Minneapolis, Mn to Chicago, Il
Ave. Duration
8 h 35 min
Frequency
Hourly
Estimated price
$45 - $110
Website
greyhound.com
Economy
$45 - $75
Flexible
$85 - $110
Bus from Chicago, Il to Atlanta, Ga
Ave. Duration
15 h 45 min
Frequency
Hourly
Estimated price
$70 - $180
Website
greyhound.com
Economy
$70 - $120
Flexible
$130 - $180
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Atlanta, GA to Florence, SC
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$35 - $60
Schedules at
southeasternstages.com
Bus from Columbia, SC to Florence, SC
Ave. Duration
1 h 20 min
Frequency
Once daily
Estimated price
$19 - $30
Schedules at
southeasternstages.com
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Minneapolis, MN to Chicago
Ave. Duration
8 h 40 min
Frequency
4 times a day
Estimated price
$35 - $55
Book at
megabus.com
Bus from Chicago to Marta Civic Center Station - Nb
Ave. Duration
14 h 5 min
Frequency
Twice daily
Estimated price
$60 - $85
Book at
megabus.com
Bus from Atlanta GA to Columbia, SC
Ave. Duration
4 h 15 min
Frequency
Twice daily
Estimated price
$21 - $35
Book at
megabus.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Southwest Airlines, Delta and American Airlines offer flights from Minneapolis Airport to Charlotte Airport.

Search flights

There are 17+ hotels available in South Carolina. Prices start at $51 USD per night.

More details

The best way to get from Minneapolis to Minneapolis Airport is to tram which takes 18 min and costs .

More details