Rome2Rio

How to get fromMilwaukee to Sikestonby bus, plane, taxi, train or car

Find Transport to Sikeston

See all options

There are 8 ways to get from Milwaukee to Sikeston by bus, plane, taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Chicago O'Hare International Airport, fly to Cape Girardeau Municipal Airport, taxi

    best
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    3. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    4h 57m
    $165–293

  2. Drive 482.5 mi

    cheapest
    1. Drive from Milwaukee to Sikestoncar car 482.5 mi
    8h 4m
    $88–128

  3. Bus

    1. Take the bus from Water & Chicago - Circle K to Flying J - Matthewsbus bus Milwaukee
    9h 19m
    $114–232

  4. Train, taxi (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train
    3. Take the taxi from Fulton Amtrak Station to Sikestontaxi taxi
    11h 7m
    $244–422

  5. Bus to Chicago O'Hare International Airport, fly to Barkley Regional Airport, taxi

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    3. Take the taxi from Barkley Regional Airport (PAH) to Sikestontaxi taxi
    5h 28m
    $335–788

  6. Fly General Mitchell International Airport to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    7h 11m
    $233–1,142

  7. Bus to Chicago O'Hare International Airport, fly to Williamson County Regional Airport, bus

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    3. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    7h 8m
    $157–388

  8. Fly General Mitchell International Airport to Cape Girardeau Municipal Airport, taxi

    1. Fly from General Mitchell International Airport (MKE) to Cape Girardeau Municipal Airport (CGI)plane plane MKE - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    5h 41m
    $242–849

Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights

Calendar7Weekly Planes
Duration1h 35mAverage Duration
Ticket$62Cheapest Price
See schedules

Questions & Answers

What companies run services between Milwaukee, WI, USA and Sikeston, MO, USA?

Tornado Bus Company operates a bus from Water & Chicago - Circle K to Flying J - Matthews once daily. Tickets cost $90–210 and the journey takes 9h 5m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Milwaukee

Trips to Sikeston

Popular routes