There are 8 ways to get from Milwaukee to Santee by plane, train (Amtrak), bus (Flixbus, Greyhound), car, taxi, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to San Diego International Airport
best- Fly from General Mitchell International Airport (MKE) to San Diego International Airport (SAN)MKE - SAN
7h 32m$248–1,215Bus to Chicago O'Hare International Airport, fly to San Diego International Airport
cheapest- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Fly from Chicago O'Hare International Airport (ORD) to San Diego International Airport (SAN)ORD - SAN
8h 58m$141–413Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Station
- Take the train from Chicago Union Station to Fullerton Amtrak Station
- Take the train from Fullerton Amtrak Station to San Diego Old Town Transportation Center
2d 1h$205–450Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Station
- Take the bus from Chicago Bus Station to St Louis Bus Station
- Take the bus from St Louis Bus Station to Phoenix Bus Station
- Take the bus from Phoenix Bus Station to El Cajon Transit Center
2d 1h$220–634Drive 2,099.5 mi
- Drive from Milwaukee to Santee2,099.5 mi
33h 16m$384–554Fly General Mitchell International Airport to Mcclellan–Palomar Airport, taxi
- Fly from General Mitchell International Airport (MKE) to Mcclellan–Palomar Airport (CLD)MKE - CLD
- Take the taxi from Mcclellan–Palomar Airport (CLD) to Santee
8h 14m$272–930Train to Chicago Midway International Airport, fly to San Diego International Airport
- Take the train from Milwaukee to Chicago Union Station
- Fly from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN)MDW - SAN
9h 34m$191–777Bus, train
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Take the train from Chicago Union Station to Yuma Amtrak
- Take the bus from Yuma County Area Transit to El Cajon Transit Center
2d 22h$275–780
Milwaukee to Santee by train and tram (Amtrak)
Questions & Answers
The cheapest way to get from Milwaukee to Santee is to train which costs $200 - $450 and takes 2 days 1h.
The fastest way to get from Milwaukee to Santee is to fly which takes 7h 32m and costs $240 - $1,300.
No, there is no direct train from Milwaukee to Santee station. However, there are services departing from Milwaukee and arriving at Santee Town Center Station via Chicago Union Station, Fullerton Amtrak Station, Old Town Station and El Cajon Station. The journey, including transfers, takes approximately 2 days 1h.
The distance between Milwaukee and Santee is 1781 miles. The road distance is 2111.7 miles.
The best way to get from Milwaukee to Santee without a car is to train which takes 2 days 1h and costs $200 - $450.
It takes approximately 7h 32m to get from Milwaukee to Santee, including transfers.
Milwaukee to Santee train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to Santee is to fly which takes 7h 32m and costs $240 - $1,300. Alternatively, you can train, which costs $200 - $450 and takes 2 days 1h, you could also bus, which costs $220 - $650 and takes 2 days 1h.
Santee is 2h behind Milwaukee. It is currently 11:42 AM in Milwaukee and 9:42 AM in Santee.
Milwaukee to Santee train services, operated by Amtrak, arrive at Chicago Union Station.
What companies run services between Milwaukee, WI, USA and Santee, CA, USA?
Southwest Airlines flies from General Mitchell International Airport (MKE) to San Diego International Airport (SAN) 5 times a day. Alternatively, you can take a train from Milwaukee to Santee Town Center Station via Chicago Union Station, Fullerton Amtrak Station, San Diego Old Town Transportation Center, Old Town Station, and El Cajon Station in around 2d 1h.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- southwest.com
Flights from General Mitchell International Airport to San Diego International Airport
- Ave. Duration
- 4h 22m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $240–1,100
Flights from General Mitchell International Airport to San Diego International Airport via Denver
- Ave. Duration
- 6h 10m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $240–1,100
Flights from General Mitchell International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 6h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,100
Flights from General Mitchell International Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 6h 12m
- When
- Monday, Friday, and Sunday
- Estimated price
- $240–1,100
Flights from General Mitchell International Airport to San Diego International Airport via Chicago Midway International Airport
- Ave. Duration
- 6h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $250–1,100
Flights from Chicago O'Hare International Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 6h 10m
- When
- Monday
- Estimated price
- $140–600
Flights from Chicago Midway International Airport to San Diego International Airport
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $160–700
Flights from Chicago Midway International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 5h 55m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $160–750
Flights from Chicago Midway International Airport to San Diego International Airport via Omaha
- Ave. Duration
- 6h
- When
- Monday
- Estimated price
- $160–700
Flights from Chicago Midway International Airport to San Diego International Airport via Denver
- Ave. Duration
- 6h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $160–750
Flights from Chicago Midway International Airport to San Diego International Airport via Kansas City
- Ave. Duration
- 6h 10m
- When
- Thursday
- Estimated price
- $160–700
- Website
- united.com
Flights from General Mitchell International Airport to Mcclellan–Palomar Airport via Denver
- Ave. Duration
- 6h 48m
- When
- Every day
- Estimated price
- $200–900
Flights from Chicago O'Hare International Airport to San Diego International Airport
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $130–600
Flights from Chicago O'Hare International Airport to San Diego International Airport via Denver
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $130–600
- Website
- aa.com
Flights from General Mitchell International Airport to Mcclellan–Palomar Airport via Phoenix
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $200–900
Flights from Chicago O'Hare International Airport to San Diego International Airport
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $130–600
- Website
- jsx.com
Flights from General Mitchell International Airport to Mcclellan–Palomar Airport via Las Vegas
- Ave. Duration
- 6h 21m
- When
- Monday, Friday, and Sunday
- Estimated price
- $150–900
- Website
- alaskaair.com
Flights from Chicago O'Hare International Airport to San Diego International Airport
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $130–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $23–40
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Twice daily
- Estimated price
- $150–350
- Website
- https://www.amtrak.com/home.html
Train from Fullerton Amtrak Station to San Diego Old Town Transportation Center
- Ave. Duration
- 2h 9m
- Frequency
- Every 2 hours
- Estimated price
- $28–33
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Yuma Amtrak
- Ave. Duration
- 2d 12h
- Frequency
- 3 times a week
- Estimated price
- $200–650
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $200–600
- Coach Seat short notice purchase
- $310–650
- Business - advance purchase
- $430–1,700
- Business Class
- $550–1,400
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $20–28
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–85
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $20–60
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Phoenix Bus Station
- Ave. Duration
- 30h 50m
- Frequency
- Twice daily
- Estimated price
- $120–390
- Website
- https://www.greyhound.com/
Bus from Phoenix Bus Station to El Cajon Transit Center
- Ave. Duration
- 7h 10m
- Frequency
- 5 times a week
- Estimated price
- $45–100
- Website
- https://www.greyhound.com/
Bus from Yuma County Area Transit to El Cajon Transit Center
- Ave. Duration
- 3h 45m
- Frequency
- 5 times a week
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- $35–38
- Schedules at
- coachusa.com
- Ave. Duration
- 41 min
- Estimated price
- $120–150
Yellow Cab of North County
- Phone
- +1 760-444-4444
- Website
- driveu.com
Craig's Cabs
- Phone
- +1 760-722-2227
- Website
- craigscabs.com
Coastal Cab
- Phone
- +1 760-722-7472
- Website
- coastal-cab.com
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More Questions & Answers
Yes, the driving distance between Milwaukee to Santee is 2112 miles. It takes approximately 33h 16m to drive from Milwaukee to Santee.
There are 1169+ hotels available in Santee.









