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There are 6 ways to get from Milwaukee to La Crosse by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  3h 19m

  1. Take the train from Milwaukee Intermodal Station to La Crosse Amtrak Station Empire Builder

$35 - $55

Cheapest option

Bus via Madison  •  5h 25m

  1. Take the bus from Milwaukee Intermodal to UW Madison Langdon St Daily Route / ...
  2. Take the bus from Madison, WI - Chazen UW Madison to La Crosse, WI - UW La Crosse - Sanford Hall College Connection

$33 - $65

4 alternative options

Bus  •  4h 10m

  1. Take the bus from Milwaukee to La Crosse 966

$40 - $65

Drive  •  3h 30m

  1. Drive from Milwaukee to La Crosse 212 miles

$20 - $30

Fly from Milwaukee  •  4h 46m

  1. Fly from Milwaukee (MKE) to La Crosse (LSE) MKE - LSE

$192 - $989

Wisconsin Coach Lines to Chicago O'Hare, fly  •  4h 14m

  1. Take the Wisconsin Coach Lines from Milwaukee, WI - Amtrak to O'Hare Term 1,2,3
  2. Fly from Chicago O'Hare (ORD) to La Crosse (LSE) ORD - LSE

$191 - $708

Questions & Answers

The cheapest way to get from Milwaukee to La Crosse is to drive which costs $20 - $30 and takes 3h 30m.

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The quickest way to get from Milwaukee to La Crosse is to train which costs $35 - $55 and takes 3h 19m.

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Yes, there is a direct bus departing from Milwaukee and arriving at La Crosse. Services depart once daily, and operate every day. The journey takes approximately 4h 10m.

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Yes, there is a direct train departing from Milwaukee Intermodal Station station and arriving at La Crosse Amtrak Station station. Services depart three times a day, and operate every day. The journey takes approximately 3h 19m.

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The distance between Milwaukee and La Crosse is 176 miles. The road distance is 212 miles.

Get driving directions

The best way to get from Milwaukee to La Crosse without a car is to train which takes 3h 19m and costs $35 - $55.

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The train from Milwaukee Intermodal Station to La Crosse Amtrak Station takes 3h 19m including transfers and departs three times a day.

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Milwaukee to La Crosse bus services, operated by Jefferson Lines, depart from Milwaukee station.

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Milwaukee to La Crosse train services, operated by Amtrak, arrive at Milwaukee Intermodal Station.

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The best way to get from Milwaukee to La Crosse is to train which takes 3h 19m and costs $35 - $55. Alternatively, you can bus, which costs $40 - $65 and takes 4h 10m, you could also fly, which costs $190 - $1,000 and takes 4h 46m.

Mode details

Map of how to get from Milwaukee to La Crosse.
Launch map view
  • Distance: 176.4 miles
  • Duration: 3h 19m

What companies run services between Milwaukee, WI, USA and La Crosse, WI, USA?

Amtrak operates a train from Milwaukee to La Crosse 3 times a day. Tickets cost $35 - $55 and the journey takes 3h 19m. Alternatively, Jefferson Lines operates a bus from Milwaukee to La Crosse once daily. Tickets cost $40 - $65 and the journey takes 4h 10m.

Airlines
American Airlines
Website
aa.com
Flights from Milwaukee to La Crosse via Chicago O'Hare
Ave. Duration
4h 15m
When
Every day
Estimated price
$180 - $950
Flights from Chicago O'Hare to La Crosse
Ave. Duration
1h 13m
When
Every day
Estimated price
$260 - $850
Delta
Website
delta.com
Flights from Milwaukee to La Crosse via Minneapolis
Ave. Duration
4h 9m
When
Every day
Estimated price
$170 - $950
Flights from Milwaukee to La Crosse via Detroit
Ave. Duration
6h 15m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $1,000
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Milwaukee Intermodal Station to La Crosse Amtrak Station
Ave. Duration
3h 19m
Frequency
3 times a day
Estimated price
$35 - $55
Website
amtrak.com
Coach Seat
$35 - $55
Premium
$200 - $280
Flexi Coach Seat
$60 - $90
Business Seat
$60 - $85
Bus operators
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Milwaukee to La Crosse
Ave. Duration
4h 10m
Frequency
Once daily
Estimated price
$40 - $65
Book at
jeffersonlines.com
Badger Bus
Website
badgerbus.com
Bus from Milwaukee Intermodal to UW Madison Langdon St
Ave. Duration
1h 40m
Frequency
Every 4 hours
Estimated price
$16 - $24
Schedules at
badgerbus.com
Book at
badgerbus.com
Bus from Madison, WI - Chazen UW Madison to La Crosse, WI - UW La Crosse - Sanford Hall
Ave. Duration
2h 45m
Frequency
Every 4 hours
Estimated price
$23 - $35
Schedules at
badgerbus.com
Book at
badgerbus.com
Amtrak Thruway

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Thruway
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Bus from Milwaukee Intermodal to UW Madison Langdon St
Ave. Duration
1h 30m
Frequency
Every 4 hours
Estimated price
$20 - $30
Website
amtrak.com
Lamers Bus Lines
Phone
+1 800-236-1240
Website
golamers.com
Bus from Milwaukee, WI to Madison
Ave. Duration
1h 50m
Frequency
Once daily
Estimated price
$19 - $25
Schedules at
golamers.com
Coach USA
Phone
201-225-7500
Website
coachusa.com
Bus from Milwaukee, WI - Amtrak to O'Hare Term 1,2,3
Ave. Duration
1h 50m
Frequency
Hourly
Estimated price
$21 - $35
Book at
Coach USA

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

There is no direct flight from Milwaukee Airport to La Crosse Airport. The quickest flight takes 3h 14m and has one stopover.

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Milwaukee to La Crosse bus services, operated by Jefferson Lines, arrive at La Crosse station.

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Milwaukee to La Crosse train services, operated by Amtrak, arrive at La Crosse Amtrak Station.

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Yes, the driving distance between Milwaukee to La Crosse is 212 miles. It takes approximately 3h 30m to drive from Milwaukee to La Crosse.

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United Airlines, American Airlines and Delta offer flights from Milwaukee Airport to La Crosse Airport.

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Book your Milwaukee to La Crosse train tickets online with Rome2rio.

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There are 42+ hotels available in La Crosse. Prices start at $59 USD per night.

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The best way to get from Milwaukee to Milwaukee Airport is to Wisconsin Coach Lines which takes 20m and costs $2 - $15.

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