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How to get fromMilwaukee to Irvineby plane, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car or bus

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There are 5 ways to get from Milwaukee to Irvine by plane, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Mitchell International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to John Wayne Airport Orange County (SNA)plane plane MKE - SNA
    7h 33m
    $252–1,280

  2. Bus to Chicago O'Hare International Airport, fly

    cheapest
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to John Wayne Airport Orange County (SNA)plane plane ORD - SNA
    7h 21m
    $155–538

  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    46h 36m
    $327–1,545

  4. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to Anaheimbus bus
    2d 3h

  5. Drive 2,036.3 mi

    1. Drive from Milwaukee to Irvinecar car 2,036.3 mi
    32h 14m
    $372–537

Milwaukee to Irvine by train (Amtrak)

Calendar13Weekly Trains
Duration46h 36mAverage Duration
Ticket$327Cheapest Price
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Questions & Answers

What companies run services between Milwaukee, WI, USA and Irvine, CA, USA?

Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a train from Milwaukee to Tustin via Chicago Union Station, Fullerton Amtrak Station, and Fullerton in around 46h 36m.

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