There are 6 ways to get from Milwaukee to Irvine by plane, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to John Wayne Airport Orange County
best- Fly from General Mitchell International Airport (MKE) to John Wayne Airport Orange County (SNA)MKE - SNA
7h 18m$242–1,180Bus to Chicago O'Hare International Airport, fly to John Wayne Airport Orange County
cheapest- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Fly from Chicago O'Hare International Airport (ORD) to John Wayne Airport Orange County (SNA)ORD - SNA
7h 22m$155–538Train (Amtrak)
- Take the train from Milwaukee to Chicago Union StationHiawatha Service / ...
- Take the train from Chicago Union Station to Fullerton Amtrak StationSouthwest Chief
46h 36m$327–1,545Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Station
- Take the bus from Chicago Bus Station to St Louis Bus Station
- Take the bus from St Louis Bus Station to Los Angeles Union Station
- Take the bus from Los Angeles to Anaheim
2d 3hDrive 2,036.3 mi
- Drive from Milwaukee to Irvine2,036.3 mi
32h 14m$372–537Fly General Mitchell International Airport to San Diego International Airport, train
- Fly from General Mitchell International Airport (MKE) to San Diego International Airport (SAN)MKE - SAN
- Take the train from San Diego Old Town Transportation Center to Irvine
9h 44m$310–1,414
Milwaukee to Irvine by train (Amtrak)
Questions & Answers
The cheapest way to get from Milwaukee to Irvine is to bus and fly which costs $150 - $550 and takes 7h 22m.
The fastest way to get from Milwaukee to Irvine is to fly which takes 7h 18m and costs $240 - $1,200.
No, there is no direct bus from Milwaukee station to Irvine. However, there are services departing from Milwaukee Intermodal Station and arriving at Main-Harvard via Chicago Bus Station, St Louis Bus Station, Los Angeles and Artic - Dock 4. The journey, including transfers, takes approximately 2 days 3h.
No, there is no direct train from Milwaukee to Irvine. However, there are services departing from Milwaukee and arriving at Tustin via Chicago Union Station and Fullerton. The journey, including transfers, takes approximately 46h 36m.
The distance between Milwaukee and Irvine is 1752 miles. The road distance is 2048.2 miles.
The best way to get from Milwaukee to Irvine without a car is to train which takes 46h 36m and costs $320 - $1,600.
It takes approximately 7h 18m to get from Milwaukee to Irvine, including transfers.
Milwaukee to Irvine bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Milwaukee to Irvine train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to Irvine is to fly which takes 7h 18m and costs $240 - $1,200. Alternatively, you can train, which costs $320 - $1,600 and takes 46h 36m, you could also bus, which costs and takes 2 days 3h.
What companies run services between Milwaukee, WI, USA and Irvine, CA, USA?
Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to John Wayne Airport Orange County (SNA) every 3 hours. Alternatively, you can take a train from Milwaukee to Tustin via Chicago Union Station, Fullerton Amtrak Station, and Fullerton in around 46h 36m.
- Website
- southwest.com
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 6h 38m
- When
- Monday, Friday, and Sunday
- Estimated price
- $240–1,100
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 10m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- $240–1,100
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 6h 35m
- When
- Monday, Friday, and Saturday
- Estimated price
- $250–1,200
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Austin
- Ave. Duration
- 7h 20m
- When
- Monday
- Estimated price
- $300–1,300
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Dallas
- Ave. Duration
- 9h 50m
- When
- Friday
- Estimated price
- $280–1,200
Flights from Chicago O'Hare International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 15m
- When
- Friday and Sunday
- Estimated price
- $130–650
Flights from Chicago O'Hare International Airport to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 6h 25m
- When
- Monday
- Estimated price
- $130–650
Flights from Chicago O'Hare International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 6h 25m
- When
- Monday
- Estimated price
- $140–650
Flights from General Mitchell International Airport to San Diego International Airport
- Ave. Duration
- 4h 25m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- $280–1,300
Flights from General Mitchell International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 6h 8m
- When
- Monday, Friday, and Sunday
- Estimated price
- $280–1,300
Flights from General Mitchell International Airport to San Diego International Airport via Denver
- Ave. Duration
- 6h 8m
- When
- Monday and Sunday
- Estimated price
- $280–1,300
Flights from General Mitchell International Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 6h 21m
- When
- Monday to Friday
- Estimated price
- $290–1,300
Flights from General Mitchell International Airport to San Diego International Airport via Chicago Midway
- Ave. Duration
- 6h 20m
- When
- Monday
- Estimated price
- $290–1,300
- Website
- united.com
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 36m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $240–1,100
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Chicago O'Hare International Airport
- Ave. Duration
- 7h 37m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Chicago O'Hare International Airport to John Wayne Airport Orange County
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $130–650
Flights from Chicago O'Hare International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $130–650
- Website
- aa.com
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 6h 46m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $250–1,200
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Chicago O'Hare International Airport
- Ave. Duration
- 8h 26m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,100
Flights from Chicago O'Hare International Airport to John Wayne Airport Orange County
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $130–650
Flights from Chicago O'Hare International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $140–650
Flights from General Mitchell International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 6h 6m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $280–1,300
- Website
- delta.com
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Salt Lake City
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $250–1,200
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Minneapolis
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $250–1,200
Flights from Chicago O'Hare International Airport to John Wayne Airport Orange County via Salt Lake City
- Ave. Duration
- 6h 25m
- When
- Sunday
- Estimated price
- $140–650
Flights from General Mitchell International Airport to San Diego International Airport via Minneapolis
- Ave. Duration
- 6h 23m
- When
- Thursday to Sunday
- Estimated price
- $290–1,300
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Twice daily
- Estimated price
- $300–1,500
- Website
- https://www.amtrak.com/home.html
Train from San Diego Old Town Transportation Center to Irvine
- Ave. Duration
- 1h 38m
- Frequency
- Every 2 hours
- Estimated price
- $24–28
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $19–65
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Los Angeles Union Station
- Ave. Duration
- 38h 45m
- Frequency
- Twice daily
- Estimated price
- $120–460
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–75
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Los Angeles to Anaheim
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- $35–38
- Schedules at
- coachusa.com
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More Questions & Answers
Milwaukee to Irvine bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Irvine is 2h behind Milwaukee. It is currently 8:57 AM in Milwaukee and 6:57 AM in Irvine.
Milwaukee to Irvine train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Milwaukee to Irvine is 2048 miles. It takes approximately 32h 14m to drive from Milwaukee to Irvine.
There are 1359+ hotels available in Irvine.









