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How to get fromMilwaukee to Irvineby plane, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, bus or train

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There are 6 ways to get from Milwaukee to Irvine by plane, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to John Wayne Airport Orange County

    best
    1. Fly from General Mitchell International Airport (MKE) to John Wayne Airport Orange County (SNA)planeMKE - SNA
    7h 18m
    $242–1,180
  2. Bus to Chicago O'Hare International Airport, fly to John Wayne Airport Orange County

    cheapest
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
    2. Fly from Chicago O'Hare International Airport (ORD) to John Wayne Airport Orange County (SNA)planeORD - SNA
    7h 22m
    $155–538
  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union StationtrainHiawatha Service / ...
    2. Take the train from Chicago Union Station to Fullerton Amtrak StationtrainSouthwest Chief
    46h 36m
    $327–1,545
  4. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
    4. Take the bus from Los Angeles to Anaheimbus
    2d 3h
  5. Drive 2,036.3 mi

    1. Drive from Milwaukee to Irvinecar2,036.3 mi
    32h 14m
    $372–537
  6. Fly General Mitchell International Airport to San Diego International Airport, train

    1. Fly from General Mitchell International Airport (MKE) to San Diego International Airport (SAN)planeMKE - SAN
    2. Take the train from San Diego Old Town Transportation Center to Irvinetrain
    9h 44m
    $310–1,414

Milwaukee to Irvine by train (Amtrak)

Calendar13Weekly Trains
Duration46h 36mAverage Duration
Ticket$327Cheapest Price
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Questions & Answers

What companies run services between Milwaukee, WI, USA and Irvine, CA, USA?

Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to John Wayne Airport Orange County (SNA) every 3 hours. Alternatively, you can take a train from Milwaukee to Tustin via Chicago Union Station, Fullerton Amtrak Station, and Fullerton in around 46h 36m.

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