Directions from Milwaukee to Des Moines

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Milwaukee  •  5 h 47 min

  1. Fly from Milwaukee (MKE) to Des Moines (DSM) MKE - DSM

$154 - $804

Cheapest option

Bus Burlington Trailways  •  9 h 48 min

  1. Take the bus from Milwaukee, Wi to Chicago Amtrak, Il 4737
  2. Take the bus from Chicago, IL to Des Moines, IA 1205 / ...

$62 - $117

5 alternative options

Bus to Chicago O'Hare, fly  •  5 h 18 min

  1. Take the bus from Milwaukee, WI - Amtrak to Chicago, IL - O'Hare International Airport
  2. Fly from Chicago O'Hare (ORD) to Des Moines (DSM) ORD - DSM

$173 - $735

Bus Windstar  •  9 h 20 min

  1. Take the bus from Milwaukee, WI to Chicago via Chicago
  2. Take the bus from Chicago, IL to Des Moines, IA West Bound

Train, bus  •  9 h 31 min

  1. Take the train from Milwaukee Intermodal Station Amtrak to Chicago Union Station Amtrak Hiawatha Service
  2. Take the bus from Chicago, IL to Des Moines, IA 1205 / ...

$73 - $139

Train, bus via Ottumwa, IA  •  11 h 2 min

  1. Take the train from Milwaukee Intermodal Station Amtrak to Chicago Union Station Amtrak
  2. Take the train from Chicago Union Station Amtrak to Ottumwa Amtrak
  3. Take the bus from Ottumwa, IA to Monroe, IA
  4. Take the bus from Monroe, IA to Des Moines, IA

$126 - $264

Drive  •  6 h 6 min

  1. Drive from Milwaukee to Des Moines 375.1 miles

$35 - $55

Questions & Answers

The distance between Milwaukee and Des Moines is 495 km. The road distance is 600 km.

The cheapest way to get from Milwaukee to Des Moines is to drive which costs $35 - $55 and takes 6 h 6 min.

The quickest way to get from Milwaukee to Des Moines is to bus and fly which takes 5 h 18 min and costs $170 - $750.

No, there is no direct bus from Milwaukee to Des Moines. However, there are services departing from Milwaukee, WI and arriving at Des Moines, IA via Chicago, IL. The journey, including transfers, takes approximately 9 h 20 min.

It takes approximately 5 h 47 min to get from Milwaukee to Des Moines, including transfers.

What companies run services between Milwaukee, WI, USA and Des Moines, IA, USA?

American Airlines, United Airlines and Delta fly from Milwaukee to Des Moines hourly. Alternatively, you can take a bus from Milwaukee to Des Moines via Chicago and Chicago, IL in around 9 h 20 min.

Airlines
American Airlines
Website
aa.com
Flights from Milwaukee to Des Moines via Chicago O'Hare
Ave. Duration
4 h 36 min
When
Every day
Estimated price
$150 - $800
Flights from Milwaukee to Des Moines via Charlotte
Ave. Duration
5 h 35 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $950
Flights from Milwaukee to Des Moines via Philadelphia
Ave. Duration
6 h 4 min
When
Every day
Estimated price
$250 - $1,000
Flights from Milwaukee to Des Moines via Dallas/Ft.Worth
Ave. Duration
6 h 40 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,000
Flights from Chicago O'Hare to Des Moines
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$330 - $1,100
United Airlines
Website
united.com
Flights from Milwaukee to Des Moines via Chicago O'Hare
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$170 - $850
Flights from Milwaukee to Des Moines via Denver
Ave. Duration
5 h 28 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,100
Flights from Chicago O'Hare to Des Moines
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$290 - $1,400
Delta
Website
delta.com
Flights from Milwaukee to Des Moines via Minneapolis
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$150 - $800
Flights from Milwaukee to Des Moines via Detroit
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$170 - $850
Flights from Milwaukee to Des Moines via Atlanta
Ave. Duration
5 h 56 min
When
Every day
Estimated price
$210 - $1,000
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Milwaukee Intermodal Station Amtrak to Chicago Union Station Amtrak
Ave. Duration
1 h 29 min
Frequency
Every 4 hours
Estimated price
$28 - $60
Website
amtrak.com
Coach Seat
$28 - $45
Flexi Coach Seat
$50 - $75
Business Coach Seat
$40 - $60
Room
$150 - $210
Train from Chicago Union Station Amtrak to Ottumwa Amtrak
Ave. Duration
4 h 53 min
Frequency
Once daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Coach USA
Phone
201-225-7500
Website
coachusa.com
Bus from Milwaukee, WI - Amtrak to Chicago, IL - O'Hare International Airport
Ave. Duration
1 h 50 min
Frequency
Hourly
Estimated price
$21 - $35
Schedules at
coachusa.com
Book at
coachusaairportexpress.com
Windstar
Phone
+1 888-494-6378
Email
sara@gowindstar.com
Website
gowindstar.com
Bus from Chicago, IL to Des Moines, IA
Ave. Duration
6 h 40 min
Frequency
Once daily
Schedules at
gowindstar.com
Burlington Trailways
Website
burlingtontrailways.com
Bus from Chicago, IL to Des Moines, IA
Ave. Duration
6 h 50 min
Frequency
Every 3 hours
Estimated price
$45 - $80
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Ottumwa, IA to Monroe, IA
Ave. Duration
55 min
Frequency
Once a week
Estimated price
$25 - $40
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Monroe, IA to Des Moines, IA
Ave. Duration
45 min
Frequency
Once a week
Estimated price
$23 - $35
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Milwaukee, Wi to Chicago Amtrak, Il
Ave. Duration
1 h 45 min
Frequency
Every 2 hours
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $23
Flexible
$27 - $35

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.