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How to get fromMilan to Sistine Chapelby train, bus, car, plane or train (Trenitalia)

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There are 10 ways to get from Milan to Sistine Chapel by train, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Milan Rogoredo to Roma Terminitrain train 9981 / ...
    3h 24m
    €75–96

  2. Bus

    cheapest
    1. Take the bus from Milano, San Donato M3 to Florence Villa Constanza Bus Stationbus bus N528 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus bus 510 / ...
    8h 14m
    €31–73

  3. Drive 573.3 km

    1. Drive from Milan to Sistine Chapelcar car 573.3 km
    5h 19m
    €90–129

  4. Fly from Milan Linate Airport

    1. Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane plane LIN - FCO
    3h 30m
    €52–161

  5. Train via Milano Centrale

    1. Take the train from Milano Centrale to Roma Terminitrain train 9981 / ...
    3h 45m
    €77–104

  6. Train via Milan Centrale

    1. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    3h 52m
    €75–163

  7. Train to Milano Malpensa Airport, fly

    1. Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Fiumicino International Airport (FCO)plane plane MXP - FCO
    4h 6m
    €54–134

  8. Train to Genoa Cristoforo Colombo Airport, fly

    1. Take the train from Milano Rogoredo to Genova P.Za Principetrain train
    2. Fly from Genoa Cristoforo Colombo Airport (GOA) to Fiumicino International Airport (FCO)plane plane GOA - FCO
    5h 39m
    €59–190

  9. Train to Turin Caselle Airport, fly

    1. Take the train from Milano Centrale to Torino Porta di Susatrain train
    2. Fly from Turin Caselle Airport (TRN) to Fiumicino International Airport (FCO)plane plane TRN - FCO
    4h 56m
    €81–216

  10. Train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Milan Rogoredo to Bologna Centraletrain train
    2. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)plane plane BLQ - FCO
    4h 25m
    €85–209

Milan to Sistine Chapel by train, subway, and foot

Calendar35Weekly Services
Duration3h 24mAverage Duration
Ticket€75Cheapest Price
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Questions & Answers

What companies run services between Milan, Italy and Sistine Chapel, Vatican City?

ItaloTreno operates a train from Milan Rogoredo to Roma Termini 5 times a day. Tickets cost €70–95 and the journey takes 2h 59m. Alternatively, you can take a bus from Milano, San Donato M3 to Sistine Chapel via Florence Villa Constanza Bus Station, Roma, Autostazione Tiburtina, and Cavalleggeri/S. Pietro in around 8h 14m.

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Want to know more about travelling around Vatican City

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