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How to get fromMilan to Santanderby train, plane, bus, train (Trenitalia, Renfe) or car

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There are 9 ways to get from Milan to Santander by train, plane, bus, train (Trenitalia, Renfe), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Milano Malpensa Airport, fly to Santander Airport

    best
    1. Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
    2. Fly from Milano Malpensa Airport (MXP) to Santander Airport (SDR)planeMXP - SDR
    8h 11m
    €49–235
  2. Train to Milano Malpensa Airport, fly to Bilbao Airport, bus

    cheapest
    1. Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
    2. Fly from Milano Malpensa Airport (MXP) to Bilbao Airport (BIO)planeMXP - BIO
    3. Take the bus from Bilbao Intermodal to Santander E.A.bus
    7h 21m
    €42–183
  3. Bus

    1. Take the bus from Milano, Autostazione Lampugnano to San Sebastian Central Bus Stationbus
    2. Take the bus from San Sebastián / Donostia to Bilbao Intermodalbus
    3. Take the bus from Bilbao Intermodal to Santander E.A.bus
    22h 14m
    €67–101
  4. Train

    1. Take the train from Milano Centrale to Genova P.Za PrincipetrainIc
    2. Take the train from Genova P.Za Principe to Marseille St Charlestrain
    3. Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain
    4. Take the train from Madrid Chamartín to SantandertrainAlv / ...
    24h 13m
    €160–248
  5. Drive 1,332.9 km

    1. Drive from Milan to Santandercar1,332.9 km
    14h 24m
    €207–299
  6. Fly Milan Linate Airport to Santander Airport

    1. Fly from Milan Linate Airport (LIN) to Santander Airport (SDR)planeLIN - SDR
    7h 47m
    €112–292
  7. Bus to Il Caravaggio International Airport, fly to Santander Airport

    1. Take the bus from Piazza Luigi di Savoia to Bergamo Airport Bus Stationbus
    2. Fly from Il Caravaggio International Airport (BGY) to Santander Airport (SDR)planeBGY - SDR
    6h 45m
    €89–317
  8. Fly Milan Linate Airport to Bilbao Airport, bus

    1. Fly from Milan Linate Airport (LIN) to Bilbao Airport (BIO)planeLIN - BIO
    2. Take the bus from Bilbao Intermodal to Santander E.A.bus
    9h 22m
    €76–230
  9. Bus via Bordeaux

    1. Take the bus from Milano, Autostazione Lampugnano to Bordeauxbus1922
    2. Take the bus from Bordeaux to SantanderbusFlixBus 783 / ...
    26h 40m
    €86–215

Milan to Santander by bus

Calendar2Weekly Buses
Duration22h 14mAverage Duration
Ticket€67Cheapest Price
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Questions & Answers

What companies run services between Milan, Italy and Santander, Spain?

You can take a bus from Milano, Autostazione Lampugnano to Santander E.A. via San Sebastian Central Bus Station, San Sebastián / Donostia, and Bilbao Intermodal in around 22h 14m. Alternatively, you can take a train from Milano Centrale to Santander via Genova P.Za Principe, Marseille St Charles, Madrid-Puerta de Atocha-Almudena Grandes, Madrid-Atocha Cercanías, and Madrid Chamartín in around 24h 13m.

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