There are 8 ways to get from Milan to Main by plane, train (Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Milan Linate Airport
best- Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)LIN - FRA
3h 58m€44–145Bus
cheapest- Take the bus from Milano, Autostazione Lampugnano to Mainz central train station476
12h 36m€40–80Train
- Take the train from Milano Centrale to Mannheim HbfEc
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS6
8h 28m€136–197Drive 660.5 km
- Drive from Milan to Main660.5 km
6h 16m€104–149Train to Milano Malpensa Airport, fly
- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)MXP - FRA
4h 22m€61–178Train to Verona Villafranca Airport, fly
- Take the train from Milano Centrale to Verona Porta Nuova
- Fly from Verona Villafranca Airport (VRN) to Frankfurt (FRA)VRN - FRA
5h 33m€148–380Train to Turin Caselle Airport, fly
- Take the train from Milano Centrale to Torino Porta Susa
- Fly from Turin Caselle Airport (TRN) to Frankfurt (FRA)TRN - FRA
5h 30m€118–340Bus, train
- Take the bus from Milan to Mannheim Central Bus StationMarinoBus 253 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS6
14h 29m€65–92
Milan to Main by train
Questions & Answers
The cheapest way to get from Milan to Main is to bus which costs €40 - €80 and takes 12h 36m.
The fastest way to get from Milan to Main is to fly which takes 3h 58m and costs €40 - €150.
No, there is no direct bus from Milan to Main. However, there are services departing from Milano, Autostazione Lampugnano and arriving at Weisenau, Favorite-Parkhotel via Mainz, Hauptbahnhof. The journey, including transfers, takes approximately 12h 36m.
No, there is no direct train from Milan to Main. However, there are services departing from Milano Centrale and arriving at Mainz, Römisches Theater via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 8h 28m.
The distance between Milan and Main is 547 km. The road distance is 660.5 km.
The best way to get from Milan to Main without a car is to train which takes 8h 28m and costs €130 - €200.
It takes approximately 3h 58m to get from Milan to Main, including transfers.
Milan to Main bus services, operated by FlixBus, depart from Milano, Autostazione Lampugnano station.
Milan to Main train services, operated by Trenitalia EuroCity, depart from Milano Centrale station.
The best way to get from Milan to Main is to fly which takes 3h 58m and costs €40 - €150. Alternatively, you can train, which costs €130 - €200 and takes 8h 28m, you could also bus, which costs €40 - €80 and takes 12h 36m.
What companies run services between Milan, Italy and Main, Hesse, Germany?
easyJet, Lufthansa, and Air Dolomiti fly from Milan Linate Airport (LIN) to Frankfurt (FRA) every 3 hours. Alternatively, you can take a train from Milano Centrale to Mainz, Römisches Theater via Mannheim Hbf and Mannheim, Hauptbahnhof in around 8h 28m.
- Website
- lufthansa.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €90–320
Flights from Milan Linate Airport to Frankfurt via Munich
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- €90–330
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–250
Flights from Milano Malpensa Airport to Frankfurt via Munich
- Ave. Duration
- 3h 10m
- When
- Monday to Thursday
- Estimated price
- €80–260
Flights from Verona Villafranca Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €100–340
Flights from Verona Villafranca Airport to Frankfurt via Munich
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- €100–350
Flights from Turin Caselle Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €90–280
Flights from Turin Caselle Airport to Frankfurt via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €90–280
- Website
- airdolomiti.it
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €90–320
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–250
Flights from Verona Villafranca Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €100–340
Flights from Turin Caselle Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €90–280
- Website
- condor.com
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- €40–140
- Website
- swiss.com
Flights from Milano Malpensa Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 11m
- When
- Every day
- Estimated price
- €60–250
- Website
- easyjet.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €30–130
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
Train from Milano Centrale to Verona Porta Nuova
- Ave. Duration
- 1h 24m
- Frequency
- Once a week
- Estimated price
- €35–85
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €55–85
- 2nd Class
- €35–50
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 5 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +39 02-72494949
- Website
- malpensaexpress.it
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €15
- Website
- https://www.malpensaexpress.it/en/
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Verona Porta Nuova
- Ave. Duration
- 1h 13m
- Frequency
- Hourly
- Estimated price
- €14–35
- Schedules at
- trenitalia.com
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Milano Centrale to Torino Porta Susa
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €9–26
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €18–26
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Torino Porta Susa
- Ave. Duration
- 53 min
- Frequency
- Every 2 hours
- Estimated price
- €16–45
- Website
- https://www.italotreno.it/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Milano, Autostazione Lampugnano to Mainz central train station
- Ave. Duration
- 12h 15m
- Frequency
- Once daily
- Estimated price
- €40–80
- Website
- https://www.flixbus.co.uk
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Milan to Mannheim Central Bus Station
- Ave. Duration
- 11h 35m
- Frequency
- Twice a week
- Estimated price
- €50–70
- Website
- https://marinobus.it/en/
Want to know more about travelling around Germany
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More Questions & Answers
Milan to Main bus services, operated by FlixBus, arrive at Mainz central train station.
Milan to Main train services, operated by Trenitalia EuroCity, arrive at Mannheim Hbf station.
Yes, the driving distance between Milan to Main is 661 km. It takes approximately 6h 16m to drive from Milan to Main.
Book your Milan to Main train tickets online with Omio.
There are 1119+ hotels available in Main.






































