There are 7 ways to get from Milan to Lyss by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Spiez
best- Take the train from Milano Centrale to Domodossolatrain Ec
- Take the train from Domodossola to Spieztrain Ec / ...
- Take the train from Spiez to Berntrain Ic8 / ...
4h 37mCHF 60–125Bus
cheapest- Take the bus from Milano, Autostazione Lampugnano to Aostabus BlaBlaCar Bus
- Take the bus from Aosta to Bernbus FlixBus N506
7h 30mCHF 25–46Drive 349.1 km
- Drive from Milan to Lysscar 349.1 km
3h 51mCHF 57–82Train to Milano Malpensa Airport, fly to Zurich Airport, train
- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Zurich Airport (ZRH)plane MXP - ZRH
- Take the train from Zürich Flughafen to Berntrain
4h 56mCHF 116–327Train
- Take the train from Milano Centrale to Domodossolatrain Ec
- Take the train from Brig to Berntrain Ic8 / ...
4h 44mCHF 74–201Train #2
- Take the train from Milano Centrale to Domodossolatrain Re 4
- Take the train from Brig to Lysstrain Re11
5h 49mCHF 37–55Fly Milan Linate Airport to Basel, train
- Fly from Milan Linate Airport (LIN) to Basel (BSL)plane LIN - BSL
- Take the train from Basel SBB to Biel/Biennetrain
7h 32mCHF 115–309
Milan to Lyss by train
Questions & Answers
The cheapest way to get from Milan to Lyss is to bus which costs SFr 25 - SFr 50 and takes 7h 30m.
The fastest way to get from Milan to Lyss is to drive which takes 3h 51m and costs SFr 55 - SFr 85.
No, there is no direct bus from Milan to Lyss. However, there are services departing from Milano, Autostazione Lampugnano and arriving at Lyss, Mühleplatz via Aosta and Bern, Neufeld P+R. The journey, including transfers, takes approximately 7h 30m.
No, there is no direct train from Milan to Lyss. However, there are services departing from Milano Centrale and arriving at Lyss via Domodossola, Spiez and Bern. The journey, including transfers, takes approximately 4h 37m.
The distance between Milan and Lyss is 285 km. The road distance is 349.1 km.
The best way to get from Milan to Lyss without a car is to train via Spiez which takes 4h 37m and costs SFr 60 - SFr 130.
It takes approximately 4h 37m to get from Milan to Lyss, including transfers.
Milan to Lyss bus services, operated by BlaBlaCar Bus, depart from Milano, Autostazione Lampugnano station.
Milan to Lyss train services, operated by Trenitalia EuroCity, depart from Milano Centrale station.
The best way to get from Milan to Lyss is to train via Spiez which takes 4h 37m and costs SFr 60 - SFr 130. Alternatively, you can bus, which costs SFr 25 - SFr 50 and takes 7h 30m.
What companies run services between Milan, Italy and Lyss, Switzerland?
You can take a train from Milano Centrale to Lyss via Domodossola, Spiez, and Bern in around 4h 37m. Alternatively, you can take a bus from Milano, Autostazione Lampugnano to Lyss, Mühleplatz via Aosta, Bern, and Bern, Neufeld P+R in around 7h 30m.
- Website
- lufthansa.com
Flights from Milan Linate Airport to Basel via Frankfurt
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- CHF 90–550
Flights from Milan Linate Airport to Basel via Munich
- Ave. Duration
- 4h 50m
- When
- Monday to Saturday
- Estimated price
- CHF 90–550
- Website
- swiss.com
Flights from Milano Malpensa Airport to Zurich Airport
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- CHF 65–190
- Website
- ethiopianairlines.com
Flights from Milano Malpensa Airport to Zurich Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 50–180
- Website
- airfrance.com
Flights from Milan Linate Airport to Basel via Paris Charles de Gaulle
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- CHF 55–320
- Website
- austrian.com
Flights from Milan Linate Airport to Basel via Vienna
- Ave. Duration
- 4h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 85–340
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Domodossola
- Ave. Duration
- 1h 33m
- Frequency
- Every 4 hours
- Estimated price
- CHF 30–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 50–70
- 2nd Class
- CHF 30–40
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Domodossola to Spiez
- Ave. Duration
- 1h 5m
- Frequency
- 3 times a day
- Estimated price
- CHF 30–95
- Website
- https://www.sbb.ch/en
Train from Spiez to Bern
- Ave. Duration
- 33 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 13–40
- Website
- https://www.sbb.ch/en
Train from Zürich Flughafen to Bern
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- CHF 40–120
- Website
- https://www.sbb.ch/en
Train from Brig to Bern
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 30–100
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Biel/Bienne
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- CHF 23–70
- Website
- https://www.sbb.ch/en
- Phone
- +41 58 327 32 71
- Website
- bls.ch
Train from Domodossola to Spiez
- Ave. Duration
- 1h 46m
- Frequency
- Hourly
- Estimated price
- CHF 17–24
- Website
- https://www.bls.ch/en
Train from Spiez to Bern
- Ave. Duration
- 41 min
- Frequency
- 4 times a week
- Estimated price
- CHF 6–10
- Website
- https://www.bls.ch/en
Train from Brig to Lyss
- Ave. Duration
- 2h 12m
- Frequency
- Twice a week
- Estimated price
- CHF 22–35
- Website
- https://www.bls.ch/en
Train from Basel SBB to Biel/Bienne
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- CHF 13–18
- Website
- https://www.bls.ch/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 4–5
- Website
- https://www.trenord.it/en/
Train from Milano Centrale to Domodossola
- Ave. Duration
- 1h 39m
- Frequency
- Every 2 hours
- Estimated price
- CHF 8–10
- Website
- https://www.trenord.it/en/
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Milano, Autostazione Lampugnano to Aosta
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- CHF 10–20
- Website
- https://www.blablacar.co.uk/bus
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Milano, Autostazione Lampugnano to Aosta
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- CHF 10–19
- Website
- https://www.flixbus.co.uk
Bus from Aosta to Bern
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- CHF 12–22
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Milan to Lyss bus services, operated by BlaBlaCar Bus, arrive at Aosta station.
Milan to Lyss train services, operated by Trenitalia EuroCity, arrive at Domodossola station.
Yes, the driving distance between Milan to Lyss is 349 km. It takes approximately 3h 51m to drive from Milan to Lyss.
Book your Milan to Lyss train tickets online with Omio.
There are 161+ hotels available in Lyss.




























