There are 4 ways to get from Milan to Appignano by train (Trenitalia), bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Milano Centrale to Anconatrain Fr
4h 26m€104–172Bus
cheapest- Take the bus from Milano, San Donato M3 to Anconabus 420
8h 47m€41–61Drive 451 km
- Drive from Milan to Appignanocar 451 km
4h 22m€82–118Fly, bus
- Fly from Milan Linate Airport (LIN) to Raffaello Sanzio Airport (AOI)plane LIN - AOI
- Take the bus from Jesi to Filottranobus
6h 30m€107–351
Milan to Appignano by bus
Comparing Your Travel Options
The cheapest way to get from Milan to Appignano is to bus which costs €40 - €65 and takes 8h 47m.
The fastest way to get from Milan to Appignano is to drive which takes 4h 22m and costs €80 - €120.
No, there is no direct bus from Milan to Appignano. However, there are services departing from Milano, San Donato M3 and arriving at Appignano via Ancona - Via Marconi 1 and Montefano. The journey, including transfers, takes approximately 8h 47m.
No, there is no direct train from Milan to Appignano. However, there are services departing from Milano Centrale and arriving at Jesi via Ancona. The journey, including transfers, takes approximately 4h 26m.
The distance between Milan and Appignano is 473 km. The road distance is 451 km.
The best way to get from Milan to Appignano without a car is to train which takes 4h 26m and costs €100 - €180.
It takes approximately 4h 26m to get from Milan to Appignano, including transfers.
Milan to Appignano bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Milan to Appignano train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
The best way to get from Milan to Appignano is to train which takes 4h 26m and costs €100 - €180. Alternatively, you can bus, which costs €40 - €65 and takes 8h 47m.
What companies run services between Milan, Italy and Appignano, Marche, Italy?
Trenitalia Frecce operates a train from Milano Centrale to Ancona every 4 hours. Tickets cost €55–100 and the journey takes 2h 56m. Trenitalia Intercity also services this route 5 times a day. Alternatively, FlixBus operates a bus from Milano, San Donato M3 to Ancona 3 times a day. Tickets cost €35–55 and the journey takes 5h 40m.
- Website
- dat.dk
Flights from Milan Linate Airport to Raffaello Sanzio Airport
- Ave. Duration
- 1h 20m
- When
- Monday to Friday
- Estimated price
- €95–120
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Ancona
- Ave. Duration
- 2h 56m
- Frequency
- Every 4 hours
- Estimated price
- €55–100
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Ancona
- Ave. Duration
- 5h 12m
- Frequency
- 5 times a day
- Estimated price
- €45–85
- Website
- Trenitalia Intercity
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Milano, San Donato M3 to Ancona
- Ave. Duration
- 5h 40m
- Frequency
- 3 times a day
- Estimated price
- €35–55
- Website
- Flixbus
- Phone
- (+39) 0712837468
- info@atmaancona.it
- Website
- ATMA Ancona
Bus from Jesi to Filottrano
- Ave. Duration
- 35 min
- Frequency
- Every 3 hours
- Estimated price
- €2–3
- Schedules at
- ATMA Ancona
- Phone
- +39 0731 59932
- info@esitur.com
- Website
- esitur.eu
Bus from Jesi to Filottrano
- Ave. Duration
- 29 min
- Frequency
- Twice daily
- Estimated price
- €2–3
- Schedules at
- esitur.eu
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Getting to Milan from the airport
Read the travel guide
Booking & Getting There
Milan to Appignano bus services, operated by FlixBus, arrive at Ancona station.
Milan to Appignano train services, operated by Trenitalia Frecce, arrive at Ancona station.
Yes, the driving distance between Milan to Appignano is 451 km. It takes approximately 4h 22m to drive from Milan to Appignano.
There are 674+ hotels available in Appignano.