There are 9 ways to get from Midtown Manhattan to Buffalo by plane, bus, train, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Laguardia Airport to Buffalo Niagara International Airport
best- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
4h 23m$140–988Bus via 5 Av/W 50 St (Flixbus)
cheapest- Take the bus from New York Midtown to Buffalobus FlixBus 2686 / ...
9h 47m$58–102Bus
- Take the bus from New York to Buffalobus Adt N816 / ...
8h$60–280Train
- Take the train from New York Penn Station to Buffalotrain VIA Rail
9h 38m$63–123Drive 358.4 mi
- Drive from Midtown Manhattan to Buffalocar 358.4 mi
7h 15m$66–95Bus to Newark Liberty International Airport, fly to Buffalo Niagara International Airport
- Take the bus from Port Authority Bus Terminal to Terminal Bbus
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
4h 28m$140–853Fly John F. Kennedy International Airport to Buffalo Niagara International Airport
- Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane JFK - BUF
4h 26m$127–840Bus to Newark Liberty International Airport, fly to Rochester, bus
- Take the bus from Port Authority Bus Terminal to Terminal Bbus
- Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane EWR - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
5h 26m$211–619Fly Laguardia Airport to Rochester, bus
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
5h 32m$281–704
Midtown Manhattan to Buffalo by bus
Questions & Answers
The cheapest way to get from Midtown Manhattan to Buffalo is to bus via 5 Av/W 50 St which costs $55 - $110 and takes 9h 47m.
The fastest way to get from Midtown Manhattan to Buffalo is to fly which takes 4h 23m and costs $140 - $1,000.
Yes, there is a direct bus departing from New York and arriving at Buffalo. Services depart every four hours, and operate every day. The journey takes approximately 8h.
No, there is no direct train from Midtown Manhattan to Buffalo. However, there are services departing from 5 Av/53 St and arriving at Buffalo via New York Penn Station. The journey, including transfers, takes approximately 9h 38m.
The distance between Midtown Manhattan and Buffalo is 313 miles. The road distance is 360.5 miles.
The best way to get from Midtown Manhattan to Buffalo without a car is to bus which takes 8h and costs $60 - $280.
It takes approximately 4h 23m to get from Midtown Manhattan to Buffalo, including transfers.
Midtown Manhattan to Buffalo bus services, operated by Trailways, depart from New York station.
Midtown Manhattan to Buffalo train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from Midtown Manhattan to Buffalo is to fly which takes 4h 23m and costs $140 - $1,000. Alternatively, you can bus, which costs $60 - $280 and takes 8h, you could also train, which costs $60 - $130 and takes 9h 38m.
What companies run services between Midtown Manhattan, NY, USA and Buffalo, NY, USA?
American Airlines and Delta fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, Trailways operates a bus from New York to Buffalo every 4 hours. Tickets cost $60–280 and the journey takes 8h.
- Website
- united.com
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $110–800
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $140–900
Flights from Newark Liberty International Airport to Rochester
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $60–430
- Website
- delta.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $130–950
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $110–800
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $75–550
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $130–950
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–900
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $110–800
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from New York Penn Station to Buffalo
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.viarail.ca/en
- Economy Adult - same day booking
- $75–120
- Economy Adult - Advanced Booking
- $75–110
- Economy Escape Advanced Booking - Adult
- $60–80
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from New York to Buffalo
- Ave. Duration
- 8h
- Frequency
- Every 4 hours
- Estimated price
- $60–280
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $60–260
- Flexible
- $110–280
- Phone
- +1 (866) 912-6224
- olympia@coachusa.com
- Website
- newarkairportexpress.com
Bus from Port Authority Bus Terminal to Terminal B
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $25
- Book at
- https://www.coachusa.com/airport-transportation
- One Way - Adult
- $25
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $8–15
- Schedules at
- flixbus.com
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 25m
- Frequency
- Every 3 hours
- Estimated price
- $55–95
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $12–22
- Website
- https://www.greyhound.com/
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More Questions & Answers
Midtown Manhattan to Buffalo bus services, operated by Trailways, arrive at Buffalo station.
Midtown Manhattan to Buffalo train services, operated by VIA Rail, arrive at Buffalo station.
Yes, the driving distance between Midtown Manhattan to Buffalo is 361 miles. It takes approximately 7h 15m to drive from Midtown Manhattan to Buffalo.
Book your Midtown Manhattan to Buffalo bus tickets online with Omio.
There are 244+ hotels available in Buffalo.