There are 9 ways to get from Middletown to Cambridge by bus, train, car or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Recommended
Bus, train
-
Take the bus from Middletown, NY - 14 Railroad Ave to New York, Ny
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Take the train from New York Penn Station to Boston
Cheapest
Bus
-
Take the bus from Middletown, NY - 14 Railroad Ave to New York, Ny
-
Take the bus from Port Authority Bus Terminal, New York, NY to South Station, Boston, MA
Train
-
Take the train from Middletown Ny to Frank R Lautenberg Secaucus Lower Level
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Take the train from New York Penn Station to Boston
Bus via Central
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Take the bus from Middletown, NY - 14 Railroad Ave to New York, Ny
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Take the bus from New York Midtown to Boston
Drive
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Drive from Middletown to Cambridge
Bus to New York La Guardia, fly
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Take the bus from Middletown, NY - 14 Railroad Ave to New York, Ny
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Fly from New York La Guardia (LGA) to Boston (BOS)
Bus to New York JFK, fly
-
Take the bus from Middletown, NY - 14 Railroad Ave to New York, Ny
-
Fly from New York JFK (JFK) to Boston (BOS)
Bus to White Plains, fly
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Take the bus from Middletown, NY to Main St @ S Broadway
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Fly from White Plains (HPN) to Boston (BOS)
Train to Newark, fly
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Take the train from Middletown Ny to Frank R Lautenberg Secaucus Lower Level
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Fly from Newark (EWR) to Boston (BOS)
Travel safe during COVID-19
Rules to follow in United States
2m
Recommended
Travel within United States
Observe COVID-19 safety rules
COVID-19 help in United States
If you need help, visit the national COVID-19 website or call the COVID-19 Helpline 800-232-4636
Frequently Asked Questions
Yes, travel within United States is currently allowed.
Explore travel optionsDomestic travel is not restricted, but some conditions may apply
- Face masks are recommended
- There is a social distancing requirement of 2 metres
- Observe COVID-19 safety rules
The national COVID-19 helpline number in Cambridge is 800-232-4636.
Wearing a face mask on public transport in Cambridge is recommended.
The social distance requirement in Cambridge is 2 metres.
Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800-232-4636.
Last updated: 9 May 2023
Exceptions may apply, for full details: Centers for Disease control and prevention (CDC).
We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2Rio travel advice for general help.
Questions & Answers
The cheapest way to get from Middletown to Cambridge is to drive which costs $40 - $60 and takes 3h 54m.
The fastest way to get from Middletown to Cambridge is to drive. Taking this option will cost $40 - $60 and takes 3h 54m.
No, there is no direct bus from Middletown to Cambridge station. However, there are services departing from Middletown, NY - 14 Railroad Ave and arriving at South Station, Boston, MA via Port Authority Bus Terminal, New York, NY. The journey, including transfers, takes approximately 7h 8m.
The distance between Middletown and Cambridge is 183 miles. The road distance is 220.4 miles.
The best way to get from Middletown to Cambridge without a car is to bus and train which takes 6h 41m and costs $35 - $550.
It takes approximately 6h 41m to get from Middletown to Cambridge, including transfers.
Middletown to Cambridge bus services, operated by Shortline Bus, depart from Middletown, NY - 14 Railroad Ave station.
The best way to get from Middletown to Cambridge is to bus which takes 7h 8m and costs $13 - $100. Alternatively, you can train, which costs $45 - $550 and takes 7h 39m.
The quickest flight from New York La Guardia Airport to Boston Airport is the direct flight which takes 1h 10m.
Middletown to Cambridge bus services, operated by Peter Pan Bus Lines, arrive at South Station, Boston, MA.

- Distance: 183.3 miles
- Duration: 6h 41m
What companies run services between Middletown, Orange County, NY, USA and Cambridge, MA, USA?
You can take a bus from Middletown to Cambridge via New York, Ny and Port Authority Bus Terminal, New York, NY in around 7h 8m. Alternatively, you can take a train from Middletown to Cambridge via Walmart Middletown, Middletown Ny, Frank R Lautenberg Secaucus Upper Level, and New York Penn Station in around 7h 39m.

- Website
- delta.com
Flights from New York La Guardia to Boston
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $130 - $310
Flights from New York JFK to Boston
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $130 - $310
Flights from White Plains to Boston
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- $170 - $410
Flights from Newark to Boston
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $120 - $290

- Website
- jetblue.com
Flights from New York La Guardia to Boston
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $120 - $250
Flights from New York La Guardia to Boston via Martha's Vineyard
- Ave. Duration
- 2h 57m
- When
- Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- $120 - $250
Flights from New York La Guardia to Boston via Nantucket
- Ave. Duration
- 3h 4m
- When
- Friday and Sunday
- Estimated price
- $120 - $250
Flights from New York JFK to Boston
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $110 - $250
Flights from White Plains to Boston via Nantucket
- Ave. Duration
- 2h 52m
- When
- Every day
- Estimated price
- $90 - $400
Flights from Newark to Boston
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $90 - $280

- Website
- aa.com
Flights from New York La Guardia to Boston
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $120 - $250
Flights from New York JFK to Boston
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $110 - $250
Flights from Newark to Boston
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $90 - $280

- Website
- united.com
Flights from Newark to Boston
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $90 - $230

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from New York Penn Station to Boston
- Ave. Duration
- 3h 42m
- Frequency
- Every 3 hours
- Estimated price
- $50 - $490
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Seat - Adult
- $50 - $360
- Business Seat - Seniors and Active Military
- $45 - $330
- Business Seat - Child 2-12
- $25 - $180
- First Class - Adult
- $170 - $490
- First Class - Senior Citizens
- $170 - $550
- First Class - Child 2-12
- $85 - $290

Amtrak’s Northeast Regional train service serves the US’ busy northeast corridor from Virginia to Massachusetts; major stops include Boston, Providence, New York City, Philadelphia, Washington DC and Baltimore. Amenities include Wi-Fi, a quiet car, cafe and business-class seating, and travelling with a small dog or cat is permitted. Book at least 14 days in advance for a cheaper Saver Fare.
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-523-6590
- Website
- amtrak.com
Train from New York Penn Station to Boston
- Ave. Duration
- 5h 13m
- Frequency
- Every 3 hours
- Estimated price
- $30 - $220
- Website
- http://www.amtrak.com
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Book at
- https://www.amtrak.com/home.html
- Child 2-12 with paid adult
- $12 - $110
- Reserved Coach Seat
- $30 - $220
- Business Class Seat
- $110 - $260

- Phone
- +1 973-275-5555
- Website
- njtransit.com
Train from Middletown Ny to Frank R Lautenberg Secaucus Lower Level
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $13 - $20
- Website
- https://www.njtransit.com/
- Schedules at
- https://www.njtransit.com/bus-to
- Child 5-11 and Senior
- $6 - $10
- Adult
- $13 - $20

- Phone
- +1 (866) 912-6224
- shortline@coachusa.com
- Website
- coachusa.com
Bus from Middletown, NY - 14 Railroad Ave to New York, Ny
- Ave. Duration
- 2h 11m
- Frequency
- Every 3 hours
- Estimated price
- $8 - $35
- Schedules at
- coachusa.com
- Book at
- coachusa.com
- Child (0-14)
- $8 - $13
- Seniors 62+ and Special Needs
- $12 - $20
- Adults 15-61
- $17 - $26
Bus from Middletown, NY to Main St @ S Broadway
- Ave. Duration
- 1h 49m
- Frequency
- 4 times a day
- Estimated price
- $7 - $22
- Schedules at
- web.coachusa.com
- Child (0-14)
- $7 - $11
- Seniors 62+ and Special Needs
- $9 - $16
- Adults 15-61
- $14 - $22

- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Port Authority Bus Terminal, New York, NY to South Station, Boston, MA
- Ave. Duration
- 4h 20m
- Frequency
- Every 3 hours
- Estimated price
- $5 - $70
- Website
- https://peterpanbus.com/
- Adult
- $5 - $70

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from New York to Boston
- Ave. Duration
- 4h 20m
- Frequency
- Every 3 hours
- Estimated price
- $28 - $50
- Website
- https://www.greyhound.com/

- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from New York, NY to Boston, MA
- Ave. Duration
- 4h 20m
- Frequency
- 6 times a week
- Estimated price
- $26 - $35
- Website
- https://www.ourbus.com/bookTicket

- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from New York Midtown to Boston
- Ave. Duration
- 4h 15m
- Frequency
- Every 2 hours
- Estimated price
- $19 - $70
- Schedules at
- flixbus.com
- Adult
- $19 - $70
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Read the travel guideMore Questions & Answers
Yes, the driving distance between Middletown to Cambridge is 220 miles. It takes approximately 3h 54m to drive from Middletown to Cambridge.
Cape Air, JetBlue Airways and Delta offer flights from New York La Guardia Airport to Boston Airport.
There are 299+ hotels available in Cambridge. Prices start at $100 USD per night.