There are 8 ways to get from Middletown to Buffalo by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus via Syracuse, Ny  •  7 h 26 min

  1. Take the bus from Middletown, NY to Binghamton, NY 495
  2. Take the bus from Binghamton, Ny to Syracuse, Ny 206
  3. Take the bus from Syracuse, Ny to Buffalo, Ny

$59 - $116

Cheapest option

Bus  •  8 h 7 min

  1. Take the bus from Middletown, NY to Binghamton, NY Patchogue-Binghamton / ...
  2. Take the bus from Binghamton, Ny to Buffalo, Ny 252 / ...

$54 - $106

6 alternative options

Train  •  8 h 30 min

  1. Take the train from Poughkeepsie to Buffalo VIA Rail / ...

$191 - $350

Drive  •  5 h 54 min

  1. Drive from Middletown to Buffalo 318.8 miles

$30 - $45

Bus to New York La Guardia, fly  •  5 h 2 min

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from New York La Guardia (LGA) to Buffalo (BUF) LGA - BUF

$91 - $446

Bus to New York JFK, fly  •  5 h 14 min

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from New York JFK (JFK) to Buffalo (BUF) JFK - BUF

$92 - $442

Bus to Newark, fly  •  5 h 11 min

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from Newark (EWR) to Buffalo (BUF) EWR - BUF

$123 - $553

Bus, train to Philadelphia, fly  •  6 h 56 min

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Take the train from New York Penn Station to Philadelphia 30th Street Station
  3. Fly from Philadelphia (PHL) to Buffalo (BUF) PHL - BUF

$253 - $993

Questions & Answers

The cheapest way to get from Middletown to Buffalo is to drive which costs $30 - $45 and takes 5 h 54 min.

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The quickest way to get from Middletown to Buffalo is to bus and fly which costs $90 - $450 and takes 5 h 2 min.

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No, there is no direct bus from Middletown to Buffalo. However, there are services departing from Middletown, NY and arriving at Buffalo, Ny via Binghamton, Ny and Syracuse, Ny. The journey, including transfers, takes approximately 7 h 26 min.

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The distance between Middletown and Buffalo is 250 miles. The road distance is 318.8 miles.

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The best way to get from Middletown to Buffalo without a car is to bus which takes 7 h 26 min and costs $55 - $120.

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It takes approximately 7 h 26 min to get from Middletown to Buffalo, including transfers.

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Middletown to Buffalo bus services, operated by Coach USA, depart from Middletown, NY station.

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The best way to get from Middletown to Buffalo is to bus which takes 7 h 26 min and costs $55 - $120. Alternatively, you can train, which costs $190 - $350 and takes 8 h 30 min.

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The quickest flight from New York La Guardia Airport to Buffalo Airport is the direct flight which takes 1 h 21 min.

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Middletown to Buffalo bus services, operated by Greyhound USA, arrive at Buffalo, Ny station.

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Map of how to get from Middletown to Buffalo.
Launch map view
  • Distance: 250.3 miles
  • Duration: 7 h 26 min

What companies run services between Middletown, NY, USA and Buffalo, NY, USA?

You can take a bus from Middletown to Buffalo via Binghamton, NY, Binghamton, Ny, and Syracuse, Ny in around 7 h 26 min. Alternatively, VIA Rail operates a train from Middletown to Buffalo every 3 hours. Tickets cost $55 - $180 and the journey takes 6 h 39 min. Amtrak also services this route 3 times a day.

Airlines
Delta
Website
delta.com
Flights from New York La Guardia to Buffalo
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$100 - $700
Flights from New York JFK to Buffalo
Ave. Duration
1 h 38 min
When
Every day
Estimated price
$90 - $650
United Airlines
Website
united.com
Flights from New York La Guardia to Buffalo via Washington Dulles
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$220 - $1,600
Flights from Newark to Buffalo
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$120 - $850
Flights from Newark to Buffalo via Washington Dulles
Ave. Duration
3 h 24 min
When
Every day
Estimated price
$120 - $850
Flights from Philadelphia to Buffalo via Washington Dulles
Ave. Duration
3 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $1,600
American Airlines
Website
aa.com
Flights from New York La Guardia to Buffalo via Reagan Washington
Ave. Duration
3 h 36 min
When
Monday to Friday
Estimated price
$130 - $800
Flights from New York La Guardia to Buffalo via Philadelphia
Ave. Duration
3 h 38 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $800
Flights from Philadelphia to Buffalo
Ave. Duration
1 h 27 min
When
Every day
Estimated price
$200 - $1,100
Flights from Philadelphia to Buffalo via Reagan Washington
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$200 - $1,100
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Buffalo
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$100 - $650
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Poughkeepsie to Buffalo
Ave. Duration
6 h 39 min
Frequency
Every 3 hours
Estimated price
$55 - $180
Website
viarail.ca
Escape
$55 - $80
Economy
$90 - $130
Economy Plus
$130 - $180
Business
$130 - $190
Business Plus/Sleeper
$230 - $330
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Poughkeepsie Amtrak to Buffalo Exchange Street Amtrak
Ave. Duration
6 h 29 min
Frequency
3 times a day
Estimated price
$60 - $160
Website
amtrak.com
Coach Seat
$60 - $90
Flexi Coach Seat
$100 - $160
Business Coach Seat
$110 - $160
Room
$270 - $370
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New York Penn Station to Philadelphia 30th Street Station
Ave. Duration
1 h 7 min
Frequency
Hourly
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Bus operators
Coach USA
Phone
201-225-7500
Website
coachusa.com
Bus from Middletown, NY to Binghamton, NY
Ave. Duration
2 h 45 min
Frequency
Every 4 hours
Estimated price
$26 - $40
Schedules at
web.coachusa.com
Book at
sales.coachusa.com
Bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
Ave. Duration
1 h 25 min
Frequency
3 times a day
Estimated price
$19 - $60
Schedules at
web.coachusa.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Binghamton, Ny to Syracuse, Ny
Ave. Duration
1 h 15 min
Frequency
Hourly
Estimated price
$13 - $30
Website
greyhound.com
Economy
$13 - $20
Flexible
$24 - $30
Bus from Syracuse, Ny to Buffalo, Ny
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Binghamton, Ny to Buffalo, Ny
Ave. Duration
5 h 5 min
Frequency
Every 30 minutes
Estimated price
$28 - $70
Website
greyhound.com
Economy
$28 - $45
Flexible
$50 - $70

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More Questions & Answers

Yes, the driving distance between Middletown to Buffalo is 319 miles. It takes approximately 5 h 54 min to drive from Middletown to Buffalo.

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United Airlines, American Airlines and Delta offer flights from New York La Guardia Airport to Buffalo Airport.

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There are 131+ hotels available in Buffalo. Prices start at $67 USD per night.

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