There are 7 ways to get from Middletown to Buffalo by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  8 h 15 min

  1. Take the bus from Middletown, NY to Binghamton, NY 100/12/22/733* / ...
  2. Take the bus from Binghamton, Ny to Buffalo, Ny 252 / ...

$54 - $106

6 alternative options

Bus, train  •  8 h 41 min

  1. Take the bus from Middletown, NY to Binghamton, NY 495
  2. Take the bus from Binghamton to Syracuse, NY
  3. Take the train from Syracuse to Buffalo

$75 - $201

Drive  •  5 h 54 min

  1. Drive from Middletown to Buffalo 318.8 miles

$30 - $45

Bus to New York JFK, fly  •  5 h 32 min

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from New York JFK (JFK) to Buffalo (BUF) JFK - BUF

$91 - $441

Bus to Newark, fly  •  5 h 32 min

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from Newark (EWR) to Buffalo (BUF) EWR - BUF

$123 - $550

Bus to New York La Guardia, fly  •  5 h 35 min

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from New York La Guardia (LGA) to Buffalo (BUF) LGA - BUF

$91 - $443

Bus, train to Philadelphia, fly  •  7 h 24 min

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Take the train from New York Penn Station to Philadelphia 30th Street Station Amtrak
  3. Fly from Philadelphia (PHL) to Buffalo (BUF) PHL - BUF

$254 - $991

What companies run services between Middletown, NY, USA and Buffalo, NY, USA?

You can take a bus from Middletown to Buffalo via Binghamton, NY and Binghamton, Ny in around 8 h 15 min.

Airlines
Delta
Website
delta.com
Flights from New York JFK to Buffalo
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$90 - $650
Flights from New York La Guardia to Buffalo
Ave. Duration
1 h 33 min
When
Every day
Estimated price
$100 - $700
United Airlines
Website
united.com
Flights from Newark to Buffalo
Ave. Duration
1 h 24 min
When
Every day
Estimated price
$120 - $850
Flights from New York La Guardia to Buffalo via Washington Dulles
Ave. Duration
3 h 43 min
When
Every day
Estimated price
$220 - $1,600
Flights from Philadelphia to Buffalo via Washington Dulles
Ave. Duration
3 h 37 min
When
Every day
Estimated price
$280 - $1,600
American Airlines
Website
aa.com
Flights from New York La Guardia to Buffalo via Philadelphia
Ave. Duration
3 h 48 min
When
Every day
Estimated price
$130 - $800
Flights from Philadelphia to Buffalo
Ave. Duration
1 h 27 min
When
Every day
Estimated price
$200 - $1,100
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Buffalo
Ave. Duration
1 h 27 min
When
Every day
Estimated price
$100 - $650
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Syracuse to Buffalo
Ave. Duration
2 h 36 min
Frequency
Every 3 hours
Estimated price
$30 - $100
Website
viarail.ca
Escape
$30 - $50
Economy
$45 - $65
Economy Plus
$70 - $100
Business
$65 - $95
Business Plus/Sleeper
$120 - $180
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Syracuse Regional Transportation Center Amtrak to Buffalo Exchange Street Amtrak
Ave. Duration
2 h 31 min
Frequency
3 times a day
Estimated price
$35 - $85
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$60 - $90
Business Coach Seat
$55 - $85
Room
$180 - $250
Amtrak Acela Express
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New York Penn Station to Philadelphia 30th Street Station Amtrak
Ave. Duration
1 h 9 min
Frequency
Hourly
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Bus operators
Coach USA
Phone
201-225-7500
Website
coachusa.com
Bus from Middletown, NY to Binghamton, NY
Ave. Duration
2 h 45 min
Frequency
Every 2 hours
Estimated price
$26 - $40
Schedules at
web.coachusa.com
Book at
sales.coachusa.com
Bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
Ave. Duration
1 h 47 min
Frequency
Hourly
Estimated price
$19 - $60
Schedules at
web.coachusa.com
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Binghamton, Ny to Buffalo, Ny
Ave. Duration
5 h 5 min
Frequency
Hourly
Estimated price
$28 - $70
Website
greyhound.com
Economy
$28 - $45
Flexible
$50 - $70
Trailways New York
Website
trailwaysny.com
Bus from Binghamton to Syracuse, NY
Ave. Duration
1 h 25 min
Frequency
Every 4 hours
Estimated price
$19 - $65
Schedules at
trailwaysny.com
Book at
trailwaysny.com

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Questions & Answers

The distance between Middletown and Buffalo is 401 km. The road distance is 510 km.

The cheapest way to get from Middletown to Buffalo is to drive which costs $30 - $45 and takes 5 h 54 min.

The quickest way to get from Middletown to Buffalo is to bus and fly which takes 5 h 32 min and costs $120 - $550.

No, there is no direct bus from Middletown to Buffalo. However, there are services departing from Middletown, NY and arriving at Buffalo, Ny via Binghamton, Ny. The journey, including transfers, takes approximately 8 h 15 min.

It takes approximately 8 h 15 min to get from Middletown to Buffalo, including transfers.