• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
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  • Expedia

There are 10 ways to get from Middletown to Buffalo by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  8h 25m

  1. Take the train from Poughkeepsie Amtrak Station to Buffalo Amtrak Station Maple Leaf / ...

$196 - $330

Cheapest option

Bus  •  9h 14m

  1. Take the bus from Middletown, NY to Binghamton, NY Patchogue-Binghamton / ...
  2. Take the bus from Binghamton, NY - 81 Chenango Street to Buffalo Airport, NY Ny

$51 - $98

8 alternative options

Bus, train  •  9h 1m

  1. Take the bus from Middletown, NY to Binghamton, NY 495
  2. Take the bus from Binghamton, NY - 81 Chenango Street to Syracuse, NY Ny
  3. Take the train from Syracuse Regional Transportation Center to Buffalo Amtrak Station

$73 - $156

Drive  •  5h 54m

  1. Drive from Middletown to Buffalo 318.8 miles

$30 - $45

Bus to New York La Guardia, fly to Buffalo  •  5h 19m

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from New York La Guardia (LGA) to Buffalo (BUF) LGA - BUF

$91 - $431

Bus to New York JFK, fly to Buffalo  •  5h 30m

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from New York JFK (JFK) to Buffalo (BUF) JFK - BUF

$94 - $429

Bus to Newark, fly to Buffalo  •  5h 32m

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from Newark (EWR) to Buffalo (BUF) EWR - BUF

$128 - $538

Bus, train to Philadelphia, fly to Buffalo  •  6h 54m

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Take the train from New York Penn Station to Philadelphia 30th Street Station
  3. Fly from Philadelphia (PHL) to Buffalo (BUF) PHL - BUF

$253 - $978

Bus to New York La Guardia, fly to Rochester, train  •  7h 36m

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from New York La Guardia (LGA) to Rochester (ROC) LGA - ROC
  3. Take the train from Rochester Amtrak Station to Buffalo Amtrak Station

$141 - $525

Bus to Newark, fly to Rochester, train  •  7h 54m

  1. Take the bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
  2. Fly from Newark (EWR) to Rochester (ROC) EWR - ROC
  3. Take the train from Rochester Amtrak Station to Buffalo Amtrak Station

$153 - $572

Questions & Answers

The cheapest way to get from Middletown to Buffalo is to drive which costs $30 - $45 and takes 5h 54m.

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The quickest way to get from Middletown to Buffalo is to bus and fly which costs $90 - $440 and takes 5h 19m.

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No, there is no direct bus from Middletown to Buffalo. However, there are services departing from Middletown, NY and arriving at Washington St & Mohawk St via Binghamton, NY - 81 Chenango Street and 4220 Genesee St. The journey, including transfers, takes approximately 9h 14m.

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The distance between Middletown and Buffalo is 250 miles. The road distance is 318.8 miles.

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The best way to get from Middletown to Buffalo without a car is to train which takes 8h 25m and costs $190 - $330.

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It takes approximately 8h 25m to get from Middletown to Buffalo, including transfers.

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Middletown to Buffalo bus services, operated by Coach USA, depart from Middletown, NY station.

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The best way to get from Middletown to Buffalo is to train which takes 8h 25m and costs $190 - $330. Alternatively, you can bus, which costs $50 - $100 and takes 9h 14m.

Mode details

The quickest flight from New York La Guardia Airport to Buffalo Airport is the direct flight which takes 1h 31m.

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Middletown to Buffalo bus services, operated by Greyhound Canada, arrive at Buffalo Airport, NY station.

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Map of how to get from Middletown to Buffalo.
Launch map view
  • Distance: 250.3 miles
  • Duration: 8h 25m

What companies run services between Middletown, NY, USA and Buffalo, NY, USA?

Amtrak operates a train from Middletown to Buffalo 3 times a day. Tickets cost $60 - $160 and the journey takes 6h 29m. VIA Rail also services this route once daily. Alternatively, you can take a bus from Middletown to Buffalo via Binghamton, NY, Binghamton, NY - 81 Chenango Street, Buffalo Airport, NY, and 4220 Genesee St in around 9h 14m.

Airlines
United Airlines
Website
united.com
Flights from New York La Guardia to Buffalo via Washington Dulles
Ave. Duration
3h 41m
When
Every day
Estimated price
$220 - $1,600
Flights from Newark to Buffalo
Ave. Duration
1h 27m
When
Every day
Estimated price
$120 - $850
Flights from Newark to Buffalo via Washington Dulles
Ave. Duration
3h 39m
When
Every day
Estimated price
$120 - $850
Flights from Newark to Rochester
Ave. Duration
1h 24m
When
Every day
Estimated price
$120 - $600
Delta
Website
delta.com
Flights from New York La Guardia to Buffalo
Ave. Duration
1h 34m
When
Every day
Estimated price
$100 - $700
Flights from New York La Guardia to Buffalo via Boston
Ave. Duration
3h 57m
When
Monday to Friday
Estimated price
$100 - $700
Flights from New York JFK to Buffalo
Ave. Duration
1h 37m
When
Every day
Estimated price
$90 - $650
Flights from New York La Guardia to Rochester
Ave. Duration
1h 30m
When
Every day
Estimated price
$90 - $600
American Airlines
Website
aa.com
Flights from New York La Guardia to Buffalo via Philadelphia
Ave. Duration
3h 37m
When
Every day
Estimated price
$130 - $800
Flights from New York La Guardia to Buffalo via Reagan Washington
Ave. Duration
4h
When
Sunday
Estimated price
$130 - $800
Flights from Philadelphia to Buffalo
Ave. Duration
1h 24m
When
Every day
Estimated price
$200 - $1,100
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Buffalo
Ave. Duration
1h 30m
When
Every day
Estimated price
$100 - $650
Flights from New York JFK to Buffalo via Boston
Ave. Duration
3h 38m
When
Monday to Friday
Estimated price
$100 - $650
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Poughkeepsie Amtrak Station to Buffalo Amtrak Station
Ave. Duration
6h 29m
Frequency
3 times a day
Estimated price
$60 - $160
Website
amtrak.com
Coach Seat
$60 - $90
Flexi Coach Seat
$100 - $160
Business Coach Seat
$110 - $160
Room
$270 - $370
Train from Syracuse Regional Transportation Center to Buffalo Amtrak Station
Ave. Duration
2h 31m
Frequency
3 times a day
Estimated price
$35 - $85
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$60 - $90
Business Coach Seat
$55 - $85
Room
$180 - $250
Train from Rochester Amtrak Station to Buffalo Amtrak Station
Ave. Duration
1h 17m
Frequency
3 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Poughkeepsie to Buffalo
Ave. Duration
6h 39m
Frequency
Once daily
Estimated price
$80 - $150
Website
viarail.ca
Escape
$55 - $80
Economy
$80 - $120
EconomyPlus
$100 - $150
Business
$140 - $190
Train from Syracuse to Buffalo
Ave. Duration
2h 41m
Frequency
Once daily
Estimated price
$50 - $100
Website
viarail.ca
Escape
$29 - $55
Economy
$50 - $75
EconomyPlus
$70 - $100
Business
$75 - $110
Train from Rochester to Buffalo
Ave. Duration
1h 22m
Frequency
Once daily
Estimated price
$40 - $85
Website
viarail.ca
Escape
$19 - $40
Economy
$40 - $55
EconomyPlus
$55 - $85
Business
$55 - $80
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from New York Penn Station to Philadelphia 30th Street Station
Ave. Duration
1h 8m
Frequency
Every 30 minutes
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Bus operators
Coach USA
Phone
201-225-7500
Website
coachusa.com
Bus from Middletown, NY to Binghamton, NY
Ave. Duration
2h 55m
Frequency
Every 4 hours
Estimated price
$26 - $40
Schedules at
web.coachusa.com
Book at
sales.coachusa.com
Bus from Middletown, NY to New York, NY - Port Authority Bus Terminal
Ave. Duration
1h 25m
Frequency
Every 4 hours
Estimated price
$19 - $60
Schedules at
web.coachusa.com
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Binghamton, NY - 81 Chenango Street to Syracuse, NY
Ave. Duration
1h 35m
Frequency
4 times a day
Estimated price
$12 - $35
Website
Greyhound.ca
Advanced Purchase
$12 - $18
Online Fare
$13 - $28
Standard Fare
$22 - $35
Refundable
$25 - $40
Bus from Binghamton, NY - 81 Chenango Street to Buffalo Airport, NY
Ave. Duration
4h 35m
Frequency
Twice daily
Estimated price
$23 - $60
Website
Greyhound.ca
Advanced Purchase
$23 - $35
Online Fare
$29 - $50
Standard Fare
$40 - $60
Refundable
$45 - $65
Trailways New York
Phone
(800) 858-8555
Website
trailwaysny.com
Bus from Binghamton, NY to Syracuse, NY
Ave. Duration
1h 15m
Frequency
Twice daily
Estimated price
$18 - $26
Book at
trailwaysny.com

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More Questions & Answers

Yes, the driving distance between Middletown to Buffalo is 319 miles. It takes approximately 5h 54m to drive from Middletown to Buffalo.

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American Airlines, Delta and United Airlines offer flights from New York La Guardia Airport to Buffalo Airport.

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There are 140+ hotels available in Buffalo. Prices start at $59 USD per night.

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