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How to get fromMiddleburg to Key Westby taxi, plane, train, bus, shuttle, car or bus (Flixbus, Greyhound)

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There are 6 ways to get from Middleburg to Key West by taxi, plane, train, bus, shuttle, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Gainesville Regional Airport, fly

    best
    1. Take the taxi from Middleburg to Gainesville-Airport-GNVtaxi
    2. Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)planeGNV - EYW
    5h 54m
    $225–569
  2. Bus

    cheapest
    1. Take the bus from Jacksonville to Miami Airport Stationbus
    2. Take the bus from Miami Airport Station to Big Pine Keybus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    18h 44m
    $72–170
  3. Taxi, train, bus

    1. Take the taxi from Middleburg to Jacksonvilletaxi
    2. Take the train from Jacksonville to Hollywood Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    17h 11m
    $135–352
  4. Bus, shuttle

    1. Take the bus from Jacksonville to Downtown MiamibusFlixBus 2431
    2. Take a shuttle bus from Bayside Marketplace to Plaza Hotelshuttle
    17h 58m
    $115–170
  5. Drive 504.1 mi

    1. Drive from Middleburg to Key Westcar504.1 mi
    9h 15m
    $92–133
  6. Line 900 bus, bus to Jacksonville, fly

    1. Take the bus from Wells Fargo to Blanding Blvd + Orange Park Northwaybus
    2. Take the bus from Blanding Blvd + Orange Park Northway to JRTC Bay Pbus
    3. Fly from Jacksonville (JAX) to Key West International Airport (EYW)planeJAX - EYW
    7h 47m
    $305–822

Middleburg to Key West by bus and foot

Calendar15Weekly Services
Duration18h 44mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

What companies run services between Middleburg, FL, USA and Key West, FL, USA?

You can take a bus from Wells Fargo to N Roosevelt & 3rd Street via Blanding Blvd + Orange Park Northway, JRTC Bay P, Jacksonville, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 18h 44m.

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