Rome2Rio

How to get fromMiddleburg to Key Westby taxi, plane, bus, shuttle, train, car, or bus (Flixbus, Greyhound)

Find Transport to Key West

See all options

There are 6 ways to get from Middleburg to Key West by taxi, plane, bus, shuttle, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Jacksonville, fly

    best
    1. Take the taxi from Middleburg to Jacksonville-Airport-JAXtaxi taxi
    2. Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane plane JAX - EYW
    4h 5m
    $464–935

  2. Drive 504.2 mi

    cheapest
    1. Drive from Middleburg to Key Westcar car 504.2 mi
    9h 21m
    $92–133

  3. Taxi, bus, shuttle

    1. Take the taxi from Middleburg to Airporttaxi taxi
    2. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Miami Airportbus bus
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    15h 14m
    $409–553

  4. Taxi, train, bus

    1. Take the taxi from Middleburg to Jacksonvilletaxi taxi
    2. Take the train from Jacksonville to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    17h 16m
    $203–378

  5. Taxi to Gainesville Regional Airport, fly

    1. Take the taxi from Middleburg to Gainesville-Airport-GNVtaxi taxi
    2. Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane plane GNV - EYW
    4h 43m
    $201–450

  6. Bus

    1. Take the bus from Jacksonville to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    18h 11m
    $96–176

Jacksonville (JAX) to Key West International Airport (EYW) flights

Calendar61Weekly Planes
Duration4h 22mAverage Duration
Ticket$48Cheapest Price
See schedules

Questions & Answers

Map of how to get from Middleburg to Key West.ExpandLaunch map view
  • Distance: 449.7 mi
  • Duration: 4h 5m

What companies run services between Middleburg, FL, USA and Key West, FL, USA?

You can take a vehicle from Middleburg to N Roosevelt & 3rd Street via Clay County Park-N-Ride, JRTC - Express Select, Jacksonville, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 18h 11m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound