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How to get fromMiddleburg to Key Westby taxi, plane, train, bus, shuttle, car, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Middleburg to Key West by taxi, plane, train, bus, shuttle, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Gainesville Regional Airport, fly

    best
    1. Take the taxi from Middleburg to Gainesville-Airport-GNVtaxi taxi
    2. Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane plane GNV - EYW
    5h 17m
    $200–440

  2. Drive to Orlando Sanford, fly

    cheapest
    1. Drive from Middleburg to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    4h 2m
    $63–275

  3. Taxi, train, bus

    1. Take the taxi from Middleburg to Jacksonvilletaxi taxi
    2. Take the train from Jacksonville to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    17h 16m
    $222–397

  4. Bus, shuttle

    1. Take the bus from Jacksonville to Miami Golden Gladesbus bus FlixBus 2431
    2. Take a shuttle bus from Bayside Marketplace to Plaza Hotelshuttle bus
    18h 8m
    $118–158

  5. Drive 504.1 mi

    1. Drive from Middleburg to Key Westcar car 504.1 mi
    9h 21m
    $92–133

  6. Line 900 bus, bus to Jacksonville, fly

    1. Take the bus from Wells Fargo to Blanding Blvd + Orange Park Northwaybus bus
    2. Take the bus from Blanding Blvd + Orange Park Northway to JRTC Bay Pbus bus
    3. Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane plane JAX - EYW
    7h 26m
    $375–922

  7. Bus

    1. Take the bus from Jacksonville to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    18h 29m
    $74–155

Middleburg to Key West by bus and foot

Calendar15Weekly Services
Duration18h 29mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Middleburg to Key West.ExpandLaunch map view
  • Distance: 399.9 mi
  • Duration: 5h 17m

What companies run services between Middleburg, FL, USA and Key West, FL, USA?

You can take a bus from Wells Fargo to N Roosevelt & 3rd Street via Blanding Blvd + Orange Park Northway, JRTC Bay P, Jacksonville, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 18h 29m.

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