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How to get fromMichigan to St. Louisby plane, bus (Greyhound), train (Amtrak), car or bus (Flixbus)

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There are 6 ways to get from Michigan to St. Louis by plane, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Detroit

    best
    1. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)planeDTW - STL
    4h 3m
    $205–445

  2. Bus

    cheapest
    1. Take the bus from Detroit, MI to Indianapolis, INbusDetroit
    2. Take the bus from Indianapolis Union Station to St Louis Bus StationbusGreyhound US0421
    10h 15m
    $62–188

  3. Train (Amtrak)

    1. Take the train from Detroit to Chicago Union StationtrainWolverine
    2. Take the train from Chicago Union Station to St. LouistrainLincoln Service / ...
    12h 11m
    $88–377

  4. Drive 517.7 mi

    1. Drive from Detroit to St. Louiscar517.7 mi
    8h 48m
    $95–137

  5. Fly from Gerald R. Ford International Airport

    1. Fly from Gerald R. Ford International Airport (GRR) to Lambert–St. Louis International Airport (STL)planeGRR - STL
    6h 36m
    $127–807

  6. Bus via Auburn Gresham (Flixbus)

    1. Take the bus from Detroit Bus Station to ChicagobusFlixBus 2552
    2. Take the bus from Chicago to St Louis Bus StationbusFlixBus N2521
    14h
    $76–172

Michigan to St. Louis by bus

Calendar7Weekly Buses
Duration10h 15mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

What companies run services between Michigan, USA and St. Louis, MO, USA?

Delta, Southwest Airlines, and United Airlines fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Detroit, MI to St Louis Bus Station via Indianapolis Union Station in around 10h 15m.

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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