There are 9 ways to get from Michigan to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Detroit to Greenville/Spartanburg  •  3 h 22 min

  1. Fly from Detroit (DTW) to Greenville/Spartanburg (GSP) DTW - GSP

$207 - $865

Cheapest option

Bus  •  22 h 53 min

  1. Take the bus from Detroit, Mi to Columbia, Sc 1097
  2. Take the bus from Columbia, SC to Florence, SC 0985 / ...

$95 - $213

7 alternative options

Fly Detroit to Charlotte  •  3 h 44 min

  1. Fly from Detroit (DTW) to Charlotte (CLT) DTW - CLT

$282 - $470

Fly Detroit to Charleston  •  4 h 29 min

  1. Fly from Detroit (DTW) to Charleston (CHS) DTW - CHS

$169 - $343

Line 6 bus to Grand Rapids, fly to Charlotte  •  4 h 46 min

  1. Take the line 6 bus from Division & Library to Kentwood Station - Woodland
  2. Fly from Grand Rapids (GRR) to Charlotte (CLT) GRR - CLT

$227 - $642

Fly Detroit to Myrtle Beach, bus  •  5 h 51 min

  1. Fly from Detroit (DTW) to Myrtle Beach (MYR) DTW - MYR
  2. Take the bus from Myrtle Beach, SC to Florence

$142 - $480

Bus to Toledo, fly to Charlotte  •  4 h 50 min

  1. Take the bus from Ann Arbor, MI to Toledo, OH
  2. Fly from Toledo (TOL) to Charlotte (CLT) TOL - CLT

$252 - $812

Bus, train  •  24 h 6 min

  1. Take the bus from Detroit, Mi to Toledo, Oh
  2. Take the train from Toledo Amtrak to Washington Union Station Amtrak
  3. Take the train from Washington Union Station Amtrak to Florence Amtrak

$158 - $438

Drive  •  13 h 17 min

  1. Drive from Detroit to Florence 739.6 miles

$70 - $110

What companies run services between Michigan, USA and South Carolina, USA?

Delta, American Airlines and two other airlines fly from Livonia to Greenville hourly. Alternatively, you can take a bus from Detroit to Florence via Columbia, Sc and Columbia, SC in around 22 h 53 min.

Airlines
Delta
Website
delta.com
Flights from Detroit to Greenville/Spartanburg
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$280 - $1,600
Flights from Detroit to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 52 min
When
Every day
Estimated price
$280 - $1,600
Flights from Detroit to Charlotte
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$280 - $750
Flights from Detroit to Charlotte via Covington
Ave. Duration
3 h 48 min
When
Sunday
Estimated price
$280 - $750
Flights from Detroit to Charleston
Ave. Duration
2 h 4 min
When
Every day
Estimated price
$320 - $750
Flights from Detroit to Charleston via Atlanta
Ave. Duration
4 h 17 min
When
Every day
Estimated price
$320 - $750
Flights from Grand Rapids to Charlotte via Detroit
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$320 - $1,100
Flights from Grand Rapids to Charlotte via Atlanta
Ave. Duration
4 h 6 min
When
Every day
Estimated price
$320 - $1,100
Flights from Detroit to Myrtle Beach
Ave. Duration
1 h 56 min
When
Every day
Estimated price
$360 - $1,500
Flights from Detroit to Myrtle Beach via Atlanta
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$360 - $1,500
American Airlines
Website
aa.com
Flights from Detroit to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$300 - $650
Flights from Detroit to Charlotte
Ave. Duration
1 h 55 min
When
Every day
Estimated price
$280 - $750
Flights from Detroit to Charleston via Charlotte
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$350 - $700
Flights from Grand Rapids to Charlotte
Ave. Duration
1 h 53 min
When
Every day
Estimated price
$300 - $1,300
Flights from Grand Rapids to Charlotte via Chicago O'Hare
Ave. Duration
4 h 11 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $1,300
Flights from Detroit to Myrtle Beach via Charlotte
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$340 - $1,300
Flights from Detroit to Myrtle Beach via Philadelphia
Ave. Duration
4 h 22 min
When
Monday
Estimated price
$340 - $1,300
Flights from Toledo to Charlotte
Ave. Duration
1 h 47 min
When
Every day
Estimated price
$130 - $650
Flights from Toledo to Charlotte via Chicago O'Hare
Ave. Duration
4 h 18 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$150 - $700
United Airlines
Website
united.com
Flights from Detroit to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$330 - $1,700
Flights from Detroit to Charlotte via Washington Dulles
Ave. Duration
3 h 46 min
When
Every day
Estimated price
$310 - $750
Flights from Detroit to Charleston via Washington Dulles
Ave. Duration
4 h 19 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$400 - $750
Flights from Detroit to Charleston via Chicago O'Hare
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$400 - $750
Flights from Grand Rapids to Charlotte via Chicago O'Hare
Ave. Duration
4 h 7 min
When
Every day
Estimated price
$340 - $1,100
Flights from Grand Rapids to Charlotte via Washington Dulles
Ave. Duration
4 h 16 min
When
Every day
Estimated price
$340 - $1,100
Flights from Detroit to Myrtle Beach via Chicago O'Hare
Ave. Duration
4 h 19 min
When
Saturday
Estimated price
$370 - $2,000
Southwest Airlines
Website
southwest.com
Flights from Detroit to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 50 min
When
Monday to Friday
Estimated price
$320 - $2,000
Flights from Detroit to Charleston via Nashville
Ave. Duration
3 h 55 min
When
Saturday
Estimated price
$410 - $750
Flights from Detroit to Charleston via Baltimore
Ave. Duration
4 h 10 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$410 - $750
Flights from Detroit to Charleston via Chicago Midway
Ave. Duration
4 h 10 min
When
Sunday
Estimated price
$410 - $750
Flights from Grand Rapids to Charlotte via Baltimore
Ave. Duration
4 h 30 min
When
Monday to Friday
Estimated price
$370 - $1,200
Spirit Airlines
Website
spirit.com
Flights from Detroit to Myrtle Beach
Ave. Duration
1 h 49 min
When
Every day
Estimated price
$160 - $850
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Toledo Amtrak to Washington Union Station Amtrak
Ave. Duration
13 h 16 min
Frequency
Once daily
Estimated price
$80 - $230
Website
amtrak.com
Coach Seat
$80 - $120
Flexi Coach Seat
$140 - $210
Business Coach Seat
$160 - $230
Room
$340 - $470
Train from Washington Union Station Amtrak to Florence Amtrak
Ave. Duration
7 h 40 min
Frequency
4 times a day
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Bus operators
Rapid Transport
Website
ridetherapid.org
Bus from Division & Library to Kentwood Station - Woodland
Ave. Duration
29 min
Frequency
Every 30 minutes
Estimated price
$1
Schedules at
ridetherapid.org
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Myrtle Beach, SC to Florence
Ave. Duration
1 h 35 min
Frequency
Once daily
Estimated price
$18 - $25
Schedules at
southeasternstages.com
Bus from Columbia, SC to Florence, SC
Ave. Duration
1 h 38 min
Frequency
3 times a day
Estimated price
$19 - $27
Schedules at
southeasternstages.com
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Detroit, Mi to Columbia, Sc
Ave. Duration
20 h 15 min
Frequency
Hourly
Estimated price
$75 - $190
Website
greyhound.com
Economy
$75 - $130
Flexible
$140 - $190
Bus from Detroit, Mi to Toledo, Oh
Ave. Duration
1 h 10 min
Frequency
Every 15 minutes
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $19
Flexible
$22 - $28

Want to know more about travelling around United States

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Questions & Answers

The distance between Michigan and South Carolina is 1164 km. The road distance is 1183 km.

The cheapest way to get from Michigan to South Carolina is to drive which costs $70 - $110 and takes 13 h 17 min.

The quickest way to get from Michigan to South Carolina is to fly which takes 3 h 22 min and costs $200 - $900.

No, there is no direct bus from Michigan to South Carolina. However, there are services departing from Detroit, Mi and arriving at Florence, SC via Columbia, SC. The journey, including transfers, takes approximately 22 h 53 min.

It takes approximately 3 h 22 min to get from Michigan to South Carolina, including transfers.