There are 2 ways to get from Miami Airport (MIA) to Cayo Guillermo by plane, car, train or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.
Recommended
Fly to Santa Clara, drive
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Fly from Miami (MIA) to Santa Clara (SNU)
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Drive from Santa Clara to Cayo Guillermo
Fly to Camaguey, train, taxi
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Fly from Miami (MIA) to Camaguey (CMW)
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Take the train from Camaguey to Ciego de Ávila
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Take a taxi from Morón to Cayo Guillermo
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Questions & Answers
The cheapest way to get from Miami Airport (MIA) to Cayo Guillermo is to fly and drive which costs $170 - $380 and takes 5h 7m.
The quickest way to get from Miami Airport (MIA) to Cayo Guillermo is to fly and drive which costs $170 - $380 and takes 5h 7m.
The distance between Miami Airport (MIA) and Cayo Guillermo is 392 km.
It takes approximately 5h 7m to get from Miami Airport (MIA) to Cayo Guillermo, including transfers.
The quickest flight from Miami Airport to Santa Clara Airport is the direct flight which takes 1h 9m.
American Airlines offers flights from Miami Airport to Santa Clara Airport.

- Distance: 391.7 km
- Duration: 5h 7m
What companies run services between Miami Airport (MIA), USA and Cayo Guillermo, Cuba?
There is no direct connection from Miami Airport (MIA) to Cayo Guillermo. However, you can fly to Santa Clara then take the drive to Cayo Guillermo. Alternatively, you can fly to Camaguey, take the walk to Albaiza, take the bus to Amalia, take the bus to Los Coquitos, take the walk to Camaguey, take the train to Ciego de Ávila, take the walk to Ciego de Ávila, take the bus to Morón, then take the taxi to Cayo Guillermo.

- Website
- aa.com
Flights from Miami to Santa Clara
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $160 - $390
Flights from Miami to Camaguey
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $240 - $400

- Website
- en.wikipedia.org
Train from Camaguey to Ciego de Ávila
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- thebusschedule.com
- Old trains
- $1
- Second class
- $1
- First class
- $1
- Ave. Duration
- 1h 22m
- Estimated price
- $65 - $80
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