There are 9 ways to get from Messina to Assisi by car ferry, train, bus, ferry, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Car ferry, train
best- Take the car ferry from Messina Marittima to Villa San Giovanni
- Take the train from Villa S.Giovanni to Roma TerminiFa / ...
- Take the train from Roma Termini to Assisi
10h 25m€50–197Bus via Naples
cheapest- Take the bus from Messina Main Train Station to Napoli, Autostazione MetroparkItabus
- Take the bus from Napoli, Autostazione Metropark to Santa Maria degli Angeli Assisi
15h 2m€42–49Bus
- Take the bus from Messina Main Train Station to Roma, Autostazione TiburtinaItabus
- Take the bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietro
13h 55m€44–106Ferry, drive
- Take the ferry from Messina Marittima to Villa San Giovanni
- Drive from Villa San Giovanni to Assisi
9h 2m€122–192Train to Palermo Airport, fly to Perugia Sant'Egidio Airport
- Take the train from Messina Centrale to Palermo Aeroporto
- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)PMO - PEG
6h 19m€115–453Ferry, train
- Take the ferry from Messina Marittima to Villa S.GiovanniM1 / ...
- Take the train from Villa S.Giovanni to Napoli AfragolaFa / ...
- Take the train from Napoli Afragola to Roma TerminiFr / ...
- Take the train from Roma Termini to Foligno
10h 42mBus to Catania–Fontanarossa Airport, fly to Perugia Sant'Egidio Airport
- Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Fly from Catania–Fontanarossa Airport (CTA) to Perugia Sant'Egidio Airport (PEG)CTA - PEG
4h 6m€92–393Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
- Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)CTA - FLR
- Take the train from Firenze S.M.N. to Assisi
8h 58m€55–249Bus to Catania–Fontanarossa Airport, fly to Fiumicino International Airport, train
- Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Fly from Catania–Fontanarossa Airport (CTA) to Fiumicino International Airport (FCO)CTA - FCO
- Take the train from Roma Termini to Foligno
8h 59m€52–241
Messina to Assisi by car ferry, train, and bus
Questions & Answers
The cheapest way to get from Messina to Assisi is to bus via Naples which costs €40 - €50 and takes 15h 2m.
The fastest way to get from Messina to Assisi is to bus and fly which takes 4h 6m and costs €90 - €400.
No, there is no direct bus from Messina station to Assisi. However, there are services departing from Messina Main Train Station and arriving at Assisi - Piazza San Pietro via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 13h 55m.
The distance between Messina and Assisi is 811 km.
The best way to get from Messina to Assisi without a car is to car ferry and train which takes 10h 25m and costs €45 - €200.
It takes approximately 10h 25m to get from Messina to Assisi, including transfers.
Messina to Assisi bus services, operated by Itabus S.p.A., depart from Messina Main Train Station.
Messina to Assisi bus services, operated by Itabus S.p.A., arrive at Roma, Autostazione Tiburtina station.
Book your Messina to Assisi bus tickets online with Omio.
There are 2210+ hotels available in Assisi.
What companies run services between Messina, Italy and Assisi, Italy?
You can take a bus from Messina Main Train Station to Assisi - Piazza San Pietro via Roma, Autostazione Tiburtina in around 13h 55m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- ryanair.com
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €85–330
Flights from Catania–Fontanarossa Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 30m
- When
- Monday and Saturday
- Estimated price
- €70–330
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €30–150
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport via Malta
- Ave. Duration
- 3h 30m
- When
- Monday and Saturday
- Estimated price
- €30–150
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €70–160
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €35–130
- Website
- aeroitalia.com
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €23–310
- Website
- flexflight.dk
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €23–310
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €27–170
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €30–200
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Roma Termini
- Ave. Duration
- 4h 51m
- Frequency
- Every 4 hours
- Estimated price
- €55–130
- Schedules at
- trenitalia.com
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 3h 46m
- Frequency
- Every 4 hours
- Estimated price
- €40–80
- Schedules at
- trenitalia.com
Train from Napoli Afragola to Roma Termini
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €28–55
- Schedules at
- trenitalia.com
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 42m
- Frequency
- Once daily
- Estimated price
- €23–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Roma Termini
- Ave. Duration
- 6h 44m
- Frequency
- Every 4 hours
- Estimated price
- €35–90
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 5m
- Frequency
- 6 times a week
- Estimated price
- €11–25
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 54m
- Frequency
- 3 times a day
- Estimated price
- €9–23
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- €10–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Villa S.Giovanni to Roma Termini
- Ave. Duration
- 5h 50m
- Frequency
- Twice daily
- Estimated price
- €40–120
- Website
- https://www.italotreno.it/en
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 48m
- Frequency
- Once daily
- Estimated price
- €60–90
- Website
- https://www.italotreno.it/en
Train from Napoli Afragola to Roma Termini
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €21–60
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 8m
- Frequency
- 4 times a day
- Estimated price
- €21–22
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Aeroporto
- Ave. Duration
- 3h 48m
- Frequency
- Once a week
- Estimated price
- €15–50
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €35–50
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 52m
- Frequency
- Every 2 hours
- Estimated price
- €14–25
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 33m
- Frequency
- Every 4 hours
- Estimated price
- €10–35
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €23–35
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Messina Main Train Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 10h 10m
- Frequency
- Twice daily
- Estimated price
- €21–80
- Website
- https://www.itabus.it/en/home
Bus from Messina Main Train Station to Napoli, Autostazione Metropark
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- €15–22
- Website
- https://www.itabus.it/en/home
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Messina Main Train Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 10h 35m
- Frequency
- Twice daily
- Estimated price
- €21–80
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Messina Main Train Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- €24–35
- Schedules at
- autoservizisalemi.it
- Phone
- +39 075 5009641
- info@sulga.it
- Website
- sulga.it
Bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietro
- Ave. Duration
- 2h 45m
- Frequency
- 6 times a week
- Estimated price
- €23–26
- Schedules at
- sulga.it
- 2nd Class
- €23–26
- Phone
- +39 06 650.47.426
- info@tambus.it
- Website
- tambus.it
Bus from Napoli, Autostazione Metropark to Santa Maria degli Angeli Assisi
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- €25
- Schedules at
- tambus.it
- Phone
- 800 21 10 20
- saisautolineeweb@gmail.com
- Website
- saisautolinee.it
Bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- €6–9
- Schedules at
- saisautolinee.it
- Phone
- +39.090.57.37
- servizioclienti@carontetourist.it
- Website
- carontetourist.it
Car ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €2–40
- Schedules at
- carontetourist.it
- Passenger
- €2–7
- Moto
- €16–22
- Car
- €30–40
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
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