There are 8 ways to get from Messina to Assisi by bus, plane, car ferry, train, ferry, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Catania–Fontanarossa Airport, fly to Perugia Sant'Egidio Airport
best- Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Fly from Catania–Fontanarossa Airport (CTA) to Perugia Sant'Egidio Airport (PEG)CTA - PEG
4h 6m€92–383Bus via Naples
cheapest- Take the bus from Messina Main Train Station to Napoli, Autostazione MetroparkItabus
- Take the bus from Napoli, Autostazione Metropark to Santa Maria degli Angeli Assisi
14h 42m€42–49Car ferry, train
- Take the car ferry from Messina Marittima to Villa San Giovanni
- Take the train from Villa S.Giovanni to Roma TerminiFa / ...
- Take the train from Roma Termini to AssisiRe
10h 24m€48–197Bus
- Take the bus from Messina to Roma, Autostazione TiburtinaN590 / ...
- Take the bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietro
13h 5m€44–106Ferry, drive
- Take the ferry from Messina Marittima to Villa San Giovanni
- Drive from Villa San Giovanni to Assisi
9h 2m€122–182Train to Palermo Airport, fly to Perugia Sant'Egidio Airport
- Take the train from Messina Centrale to Palermo Centrale
- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)PMO - PEG
6h 45m€108–376Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
- Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)CTA - FLR
- Take the train from Firenze S.M.N. to Assisi
8h 57m€55–224Ferry, train
- Take the ferry from Messina Marittima to Villa S.GiovanniM1 / ...
- Take the train from Villa S.Giovanni to Napoli AfragolaFa / ...
- Take the train from Napoli Afragola to Roma TerminiFr / ...
- Take the train from Roma Termini to FolignoRe
11h 7m
Messina to Assisi by car ferry, train, and bus
Questions & Answers
The cheapest way to get from Messina to Assisi is to bus via Naples which costs €40 - €50 and takes 14h 42m.
The fastest way to get from Messina to Assisi is to bus and fly which takes 4h 6m and costs €90 - €390.
No, there is no direct bus from Messina to Assisi. However, there are services departing from Messina and arriving at Assisi - Piazza San Pietro via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 13h 5m.
The distance between Messina and Assisi is 777 km.
The best way to get from Messina to Assisi without a car is to car ferry and train which takes 10h 24m and costs €45 - €200.
It takes approximately 4h 6m to get from Messina to Assisi, including transfers.
Messina to Assisi bus services, operated by FlixBus, depart from Messina station.
Messina to Assisi bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Book your Messina to Assisi bus tickets online with Omio.
There are 2217+ hotels available in Assisi.
What companies run services between Messina, Italy and Assisi, Italy?
You can take a bus from Messina to Assisi - Piazza San Pietro via Roma, Autostazione Tiburtina in around 13h 5m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €75–330
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €65–250
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €70–150
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €26–150
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €30–190
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Roma Termini
- Ave. Duration
- 4h 51m
- Frequency
- Every 4 hours
- Estimated price
- €55–130
- Schedules at
- trenitalia.com
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 3h 46m
- Frequency
- Every 4 hours
- Estimated price
- €55–120
- Schedules at
- trenitalia.com
Train from Napoli Afragola to Roma Termini
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €28–55
- Schedules at
- trenitalia.com
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 42m
- Frequency
- Once daily
- Estimated price
- €23–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Roma Termini
- Ave. Duration
- 6h 44m
- Frequency
- Every 4 hours
- Estimated price
- €35–90
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 5m
- Frequency
- 6 times a week
- Estimated price
- €11–25
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 2m
- Frequency
- Twice daily
- Estimated price
- €19–26
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- €10–40
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Foligno
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €9–23
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Villa S.Giovanni to Roma Termini
- Ave. Duration
- 5h 50m
- Frequency
- Twice daily
- Estimated price
- €45–130
- Website
- https://www.italotreno.it/en
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 48m
- Frequency
- Once daily
- Estimated price
- €60–80
- Website
- https://www.italotreno.it/en
- Smart Economy
- €60–75
- Smart Flex
- €60–80
Train from Napoli Afragola to Roma Termini
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €22–60
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €10–16
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 51m
- Frequency
- Every 4 hours
- Estimated price
- €13–20
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 32m
- Frequency
- Every 4 hours
- Estimated price
- €11–16
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Foligno
- Ave. Duration
- 2h 22m
- Frequency
- Hourly
- Estimated price
- €14–25
- Website
- https://www.trenitalia.com/en.html
- Phone
- 800 21 10 20
- saisautolineeweb@gmail.com
- Website
- saisautolinee.it
Bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminal
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- €6–9
- Schedules at
- saisautolinee.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Messina to Roma, Autostazione Tiburtina
- Ave. Duration
- 9h 20m
- Frequency
- 3 times a day
- Estimated price
- €27–80
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Messina to Roma, Autostazione Tiburtina
- Ave. Duration
- 10h 10m
- Frequency
- Twice daily
- Estimated price
- €20–80
- Website
- https://www.itabus.it/en/home
Bus from Messina Main Train Station to Napoli, Autostazione Metropark
- Ave. Duration
- 7h 5m
- Frequency
- Twice daily
- Estimated price
- €15–22
- Website
- https://www.itabus.it/en/home
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Messina to Roma, Autostazione Tiburtina
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- €21–30
- Schedules at
- autoservizisalemi.it
- Phone
- +39 075 5009641
- info@sulga.it
- Website
- sulga.it
Bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietro
- Ave. Duration
- 2h 45m
- Frequency
- 6 times a week
- Estimated price
- €23–26
- Schedules at
- sulga.it
- 2nd Class
- €23–26
- Phone
- +39 06 650.47.426
- info@tambus.it
- Website
- tambus.it
Bus from Napoli, Autostazione Metropark to Santa Maria degli Angeli Assisi
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- €25
- Schedules at
- tambus.it
- Phone
- +39.090.57.37
- servizioclienti@carontetourist.it
- Website
- carontetourist.it
Car ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €2–40
- Schedules at
- carontetourist.it
- Passenger
- €2–7
- Moto
- €16–22
- Car
- €30–40
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
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