There are 5 ways to get from Mesa to St. Louis by plane, bus (Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Phoenix (PHX) to Lambert–St. Louis International Airport (STL)plane PHX - STL
5h 16m$215–1,105Bus (Greyhound)
- Take the bus from Phoenix Bus Station to St Louis Bus Stationbus Greyhound US1210
32h 21m$252–462Bus, train via Kansas City
- Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Stationbus
- Take the train from Flagstaff to Kansas Citytrain
- Take the train from Kansas City to St. Louistrain
36h 13m$349–822Drive 1,438.4 mi
- Drive from Mesa to St. Louiscar 1,438.4 mi
23h 5m$263–380Bus, train (Amtrak)
- Take the bus from North Phoenix Metro Center Transit Station to Maricopa Amtrakbus Amtrak Thruway Connecting Service
- Take the train from Maricopa Amtrak to St. Louistrain Texas Eagle
2d 4h$461–1,132
Mesa to St. Louis by tram and bus (Greyhound)
Questions & Answers
The cheapest way to get from Mesa to St. Louis is to bus which costs $250 - $470 and takes 32h 21m.
The fastest way to get from Mesa to St. Louis is to fly which takes 5h 16m and costs $210 - $1,100.
The distance between Mesa and St. Louis is 1292 miles. The road distance is 1446.8 miles.
The best way to get from Mesa to St. Louis without a car is to bus which takes 32h 21m and costs $250 - $470.
It takes approximately 5h 16m to get from Mesa to St. Louis, including transfers.
The best way to get from Mesa to St. Louis is to fly which takes 5h 16m and costs $210 - $1,100. Alternatively, you can bus, which costs $250 - $470 and takes 32h 21m.
St. Louis is 1h ahead of Mesa. It is currently 2:20 PM in Mesa and 3:20 PM in St. Louis.
Yes, the driving distance between Mesa to St. Louis is 1447 miles. It takes approximately 23h 5m to drive from Mesa to St. Louis.
There are 545+ hotels available in St. Louis.
What companies run services between Mesa, AZ, USA and St. Louis, MO, USA?
American Airlines, Frontier Airlines, and Southwest Airlines fly from Phoenix (PHX) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, Greyhound USA operates a bus from Phoenix Bus Station to St Louis Bus Station twice daily. Tickets cost $250–460 and the journey takes 30h 25m.
- Website
- southwest.com
Flights from Phoenix to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Phoenix to Lambert–St. Louis International Airport via Kansas City
- Ave. Duration
- 4h 30m
- When
- Monday, Thursday, and Friday
- Estimated price
- $210–1,100
Flights from Phoenix to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 4h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $220–1,100
- Website
- aa.com
Flights from Phoenix to Lambert–St. Louis International Airport
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- $210–1,100
- Website
- flyfrontier.com
Flights from Phoenix to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 53m
- When
- Monday
- Estimated price
- $210–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Flagstaff to Kansas City
- Ave. Duration
- 24h 27m
- Frequency
- Once daily
- Estimated price
- $270–650
- Website
- https://www.amtrak.com/home.html
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $60–140
- Website
- https://www.amtrak.com/home.html
Train from Maricopa Amtrak to St. Louis
- Ave. Duration
- 46h 35m
- Frequency
- 3 times a week
- Estimated price
- $440–1,100
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Phoenix Bus Station to St Louis Bus Station
- Ave. Duration
- 30h 25m
- Frequency
- Twice daily
- Estimated price
- $250–460
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $17–30
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from North Phoenix Metro Center Transit Station to Maricopa Amtrak
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $15–26
- Website
- https://www.amtrak.com/home.html
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