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How to get fromMesa to Chicagoby plane, bus, train or car

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There are 6 ways to get from Mesa to Chicago by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago Midway International Airport

    best
    1. Fly from Phoenix (PHX) to Chicago Midway International Airport (MDW)plane plane PHX - MDW
    5h 35m
    $144–757

  2. Bus, train via Flagstaff

    1. Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Stationbus bus FlixBus 2047
    2. Take the train from Flagstaff to Chicago Union Stationtrain train Southwest Chief
    37h 49m
    $440–987

  3. Drive 1,681.6 mi

    1. Drive from Mesa to Chicagocar car 1,681.6 mi
    29h 54m
    $307–444

  4. Fly to Chicago O'Hare International Airport

    1. Fly from Phoenix (PHX) to Chicago O'Hare International Airport (ORD)plane plane PHX - ORD
    6h 1m
    $254–557

  5. Fly to General Mitchell International Airport, train

    1. Fly from Phoenix (PHX) to General Mitchell International Airport (MKE)plane plane PHX - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    8h 9m
    $265–1,266

  6. Bus, train

    1. Take the bus from Tempe to Tucson Downtownbus bus FlixBus 2042 / ...
    2. Take the train from Tucson Amtrak Station to Chicago Union Stationtrain train Texas Eagle
    2d 7h
    $565–1,325

Mesa to Chicago by tram, bus, and train

Calendar7Weekly Services
Duration37h 49mAverage Duration
Ticket$440Cheapest Price
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Questions & Answers

What companies run services between Mesa, AZ, USA and Chicago, IL, USA?

Frontier Airlines and Southwest Airlines fly from Phoenix (PHX) to Chicago Midway International Airport (MDW) every 2 hours.

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