There are 7 ways to get from Mesa to Chicago by plane, bus, train, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago Midway International Airport
best- Fly from Phoenix (PHX) to Chicago Midway International Airport (MDW)plane PHX - MDW
5h 45m$134–657Bus, train via Flagstaff
- Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Stationbus FlixBus 2047
- Take the train from Flagstaff to Chicago Union Stationtrain Southwest Chief
37h 49m$191–1,362Bus (Greyhound)
- Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to El Paso Bus Stationbus
- Take the bus from El Paso Bus Station to Denver Union Stationbus
- Take the bus from Denver Union Station to Chicago Bus Stationbus
47h 28m$185–592Drive 1,681.6 mi
- Drive from Mesa to Chicagocar 1,681.6 mi
29h 55m$307–444Fly to Chicago O'Hare International Airport
- Fly from Phoenix (PHX) to Chicago O'Hare International Airport (ORD)plane PHX - ORD
5h 59m$224–657Fly to General Mitchell International Airport, train
- Fly from Phoenix (PHX) to General Mitchell International Airport (MKE)plane PHX - MKE
- Take the train from Milwaukee to Chicago Union Stationtrain
8h 6m$266–1,322Bus, train
- Take the bus from Tempe to Tucson Downtownbus FlixBus 2042 / ...
- Take the train from Tucson Amtrak Station to Chicago Union Stationtrain Texas Eagle
2d 7h$238–502
Mesa to Chicago by tram, bus, and train
Questions & Answers
The cheapest way to get from Mesa to Chicago is to bus which costs $180 - $600 and takes 47h 28m.
The fastest way to get from Mesa to Chicago is to fly which takes 5h 45m and costs $130 - $700.
No, there is no direct bus from Mesa to Chicago station. However, there are services departing from University Dr & Mesa Dr and arriving at Chicago Bus Station via Tempe, Phoenix Sky Harbor Airport/44th Street Sky Train Station, El Paso Bus Station and Denver Union Station. The journey, including transfers, takes approximately 47h 28m.
The distance between Mesa and Chicago is 1473 miles. The road distance is 1691.4 miles.
The best way to get from Mesa to Chicago without a car is to bus and train via Flagstaff which takes 37h 49m and costs $190 - $1,400.
It takes approximately 5h 45m to get from Mesa to Chicago, including transfers.
Mesa to Chicago bus services, operated by Greyhound USA, depart from Phoenix Sky Harbor Airport/44th Street Sky Train Station.
The best way to get from Mesa to Chicago is to fly which takes 5h 45m and costs $130 - $700. Alternatively, you can bus, which costs $180 - $600 and takes 47h 28m.
Mesa to Chicago bus services, operated by Greyhound USA, arrive at El Paso Bus Station.
Chicago is 1h ahead of Mesa. It is currently 5:45 PM in Mesa and 6:45 PM in Chicago.
What companies run services between Mesa, AZ, USA and Chicago, IL, USA?
Frontier Airlines and Southwest Airlines fly from Phoenix (PHX) to Chicago Midway International Airport (MDW) every 3 hours. Alternatively, you can take a bus from University Dr & Mesa Dr to Chicago Bus Station via University Dr & Rural Rd, Tempe, Phoenix Sky Harbor Airport/44th Street Sky Train Station, El Paso Bus Station, and Denver Union Station in around 47h 28m.
- Website
- southwest.com
Flights from Phoenix to Chicago Midway International Airport
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- $130–650
Flights from Phoenix to Chicago Midway International Airport via Kansas City
- Ave. Duration
- 4h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Phoenix to Chicago Midway International Airport via St. Louis
- Ave. Duration
- 5h 25m
- When
- Thursday to Sunday
- Estimated price
- $140–650
Flights from Phoenix to Chicago O'Hare International Airport
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- $95–440
Flights from Phoenix to General Mitchell International Airport
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Phoenix to General Mitchell International Airport via Denver
- Ave. Duration
- 5h 17m
- When
- Tuesday to Sunday
- Estimated price
- $240–1,200
Flights from Phoenix to General Mitchell International Airport via Chicago Midway International Airport
- Ave. Duration
- 4h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $250–1,200
Flights from Phoenix to General Mitchell International Airport via St. Louis
- Ave. Duration
- 5h 30m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,200
- Website
- aa.com
Flights from Phoenix to Chicago O'Hare International Airport
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $95–440
Flights from Phoenix to General Mitchell International Airport
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Phoenix to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 36m
- When
- Saturday
- Estimated price
- $240–1,200
- Website
- united.com
Flights from Phoenix to Chicago O'Hare International Airport
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $95–440
Flights from Phoenix to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Phoenix to General Mitchell International Airport via Denver
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $240–1,200
- Website
- flyfrontier.com
Flights from Phoenix to Chicago Midway International Airport
- Ave. Duration
- 3h 17m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Phoenix to Chicago O'Hare International Airport
- Ave. Duration
- 3h 37m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $95–440
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Flagstaff to Chicago Union Station
- Ave. Duration
- 32h 43m
- Frequency
- Once daily
- Estimated price
- $160–1,300
- Website
- https://www.amtrak.com/home.html
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Website
- https://www.amtrak.com/home.html
Train from Tucson Amtrak Station to Chicago Union Station
- Ave. Duration
- 2d 2h
- Frequency
- 3 times a week
- Estimated price
- $210–460
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $29–60
- Schedules at
- flixbus.com
Bus from Tempe to Tucson Downtown
- Ave. Duration
- 1h 45m
- Frequency
- 5 times a day
- Estimated price
- $26–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to El Paso Bus Station
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $40–70
- Website
- https://www.greyhound.com/
Bus from El Paso Bus Station to Denver Union Station
- Ave. Duration
- 13h 40m
- Frequency
- 5 times a week
- Estimated price
- $60–150
- Website
- https://www.greyhound.com/
Bus from Denver Union Station to Chicago Bus Station
- Ave. Duration
- 20h 35m
- Frequency
- Once daily
- Estimated price
- $80–290
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Mesa to Chicago is 1691 miles. It takes approximately 29h 55m to drive from Mesa to Chicago.
There are 1068+ hotels available in Chicago.









