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How to get fromMesa to Buffaloby plane, bus, train, bus (Greyhound) or car

Find Transport to Buffalo

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There are 5 ways to get from Mesa to Buffalo by plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Phoenix (PHX) to Buffalo Niagara International Airport (BUF)plane plane PHX - BUF
    7h 3m
    $386–1,782

  2. Bus, train

    cheapest
    1. Take the bus from Tempe to Tucson Downtownbus bus
    2. Take the train from Tucson Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    2d 20h
    $258–706

  3. Bus, train via Flagstaff

    1. Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Stationbus bus
    2. Take the train from Flagstaff to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    2d 2h
    $266–792

  4. Bus

    1. Take the bus from Love's Chandler to 285 S East End Ave - Pomonabus bus
    2. Take the bus from Montclair Transcenter to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Columbusbus bus
    4. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    2d 19h
    $332–655

  5. Drive 2,174.6 mi

    1. Drive from Mesa to Buffalocar car 2,174.6 mi
    35h 35m
    $397–574

Mesa to Buffalo by tram, bus, and train

Calendar7Weekly Services
Duration2d 2hAverage Duration
Ticket$266Cheapest Price
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Questions & Answers

What companies run services between Mesa, AZ, USA and Buffalo, NY, USA?

Southwest Airlines, United Airlines, and American Airlines fly from Phoenix (PHX) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a vehicle from Mesa to Buffalo, NY via Love's Chandler, 285 S East End Ave - Pomona, East End Ave and Mission Blvd E, Montclair Transit Center, Montclair Transcenter, St Louis Bus Station, and Columbus - Mound St in around 2d 19h.

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Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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