There are 6 ways to get from Mesa to Ames by plane, shuttle, bus, train, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Phoenix, shuttle
best- Fly from Phoenix (PHX) to Des Moines (DSM)plane PHX - DSM
- Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State University
5h 38m$182–672Bus
cheapest- Take the bus from Phoenix Bus Station to Tulsa Bus Stationbus
- Take the bus from Tulsa to Kansas Citybus
- Take the bus from Kansas City to Des Moinesbus
- Take the bus from Des Moines to Amesbus
36h 11m$156–522Bus, train
- Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Stationbus
- Take the train from Flagstaff to Kansas Citytrain
- Take the bus from Kansas City to Des Moinesbus
- Take the bus from Des Moines to Amesbus
35h 17m$232–422Drive 1,405.8 mi
- Drive from Mesa to Amescar 1,405.8 mi
24h 54m$257–371Fly from Phoenix-Mesa Gateway Airport, shuttle
- Fly from Phoenix-Mesa Gateway Airport (AZA) to Des Moines (DSM)plane AZA - DSM
- Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State University
6h 10m$174–644Bus via Denver
- Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to El Paso Bus Stationbus
- Take the bus from El Paso Bus Station to Denver Union Stationbus
- Take the bus from Denver Union Station to Des Moinesbus
- Take the bus from Des Moines to Amesbus
41h 33m$178–527
Mesa to Ames by tram and bus
Questions & Answers
The cheapest way to get from Mesa to Ames is to bus via Denver which costs $170 - $550 and takes 41h 33m.
The fastest way to get from Mesa to Ames is to fly and shuttle which takes 5h 38m and costs $180 - $700.
No, there is no direct bus from Mesa to Ames. However, there are services departing from University Dr & Mesa Dr and arriving at Ames via Tempe, Phoenix Sky Harbor Airport/44th Street Sky Train Station, El Paso Bus Station, Denver Union Station and Des Moines. The journey, including transfers, takes approximately 41h 33m.
The distance between Mesa and Ames is 1208 miles. The road distance is 1414.1 miles.
The best way to get from Mesa to Ames without a car is to bus and train which takes 35h 17m and costs $230 - $430.
It takes approximately 5h 38m to get from Mesa to Ames, including transfers.
Mesa to Ames bus services, operated by Greyhound USA, depart from Phoenix Sky Harbor Airport/44th Street Sky Train Station.
Mesa to Ames bus services, operated by Greyhound USA, arrive at El Paso Bus Station.
Ames is 1h ahead of Mesa. It is currently 10:03 PM in Mesa and 11:03 PM in Ames.
Yes, the driving distance between Mesa to Ames is 1414 miles. It takes approximately 24h 54m to drive from Mesa to Ames.
What companies run services between Mesa, AZ, USA and Ames, IA, USA?
You can take a vehicle from Mesa Dr/Main St to Ames via 44th St/Washington, Phoenix Sky Harbor Airport/44th Street Sky Train Station, 24th St Station, Phoenix Bus Station, Tulsa, Kansas City, and Des Moines in around 36h 11m.
- Website
- southwest.com
Flights from Phoenix to Des Moines
- Ave. Duration
- 2h 40m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–480
Flights from Phoenix to Des Moines via St. Louis
- Ave. Duration
- 4h 50m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $120–550
Flights from Phoenix to Des Moines via Las Vegas
- Ave. Duration
- 5h 7m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–550
Flights from Phoenix to Des Moines via Denver
- Ave. Duration
- 5h 30m
- When
- Tuesday and Wednesday
- Estimated price
- $100–490
- Website
- aa.com
Flights from Phoenix to Des Moines
- Ave. Duration
- 2h 53m
- When
- Every day
- Estimated price
- $100–480
Flights from Phoenix to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $120–550
- Website
- allegiantair.com
Flights from Phoenix-Mesa Gateway Airport to Des Moines
- Ave. Duration
- 2h 41m
- When
- Monday, Wednesday, Friday, and Saturday
- Estimated price
- $90–450
- Website
- united.com
Flights from Phoenix to Des Moines via Denver
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $100–490
- Website
- flyfrontier.com
Flights from Phoenix to Des Moines via Denver
- Ave. Duration
- 5h 2m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–490
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Flagstaff to Kansas City
- Ave. Duration
- 24h 27m
- Frequency
- Once daily
- Estimated price
- $150–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Des Moines International Airport, IA to Ames, IA - Iowa State University
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $30–55
- Schedules at
- flixbus.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Bus from Des Moines to Ames
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $3–40
- Book at
- https://www.jeffersonlines.com
Bus from Tulsa to Kansas City
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $23–110
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Phoenix Bus Station to Tulsa Bus Station
- Ave. Duration
- 22h 35m
- Frequency
- Twice daily
- Estimated price
- $110–280
- Website
- https://www.greyhound.com/
Bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to El Paso Bus Station
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- https://www.greyhound.com/
Bus from El Paso Bus Station to Denver Union Station
- Ave. Duration
- 13h 40m
- Frequency
- 5 times a week
- Estimated price
- $65–190
- Website
- https://www.greyhound.com/
Bus from Denver Union Station to Des Moines
- Ave. Duration
- 13h
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 54+ hotels available in Ames.












