There are 6 ways to get from Merrimack to Buffalo by plane, bus (Flixbus, Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Manchester Airport
best- Fly from Manchester Airport (MHT) to Buffalo Niagara International Airport (BUF)MHT - BUF
5h 16m$264–1,427Drive 420.6 mi
cheapest- Drive from Merrimack to Buffalo420.6 mi
8h 37m$77–111Bus
- Take the bus from North Londonderry NH Transportation Center to Boston - South Station
- Take the bus from Boston to Syracuse Bus Station
- Take the bus from Syracuse Bus Station to Buffalo
12h 36m$149–308Route 3, train
- Take the bus from Nashua, NH to Boston South BusesSouthbound
- Take the train from Boston to Buffalo Depew StationLake Shore Limited
15h 55m$109–244Bus to Boston Logan Airport, fly
- Take the bus from North Londonderry NH Transportation Center to Logan International Airport
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)BOS - BUF
5h 15m$214–1,064Route 3, bus
- Take the bus from Nashua, NH to Boston South Buses
- Take the bus from Boston, MA to Syracuse, NY
- Take the bus from Syracuse, NY to Buffalo, NY
14h 8m$100–230
Manchester Airport (MHT) to Buffalo Niagara International Airport (BUF) flights
Questions & Answers
The cheapest way to get from Merrimack to Buffalo is to drive which costs $75 - $120 and takes 8h 37m.
The fastest way to get from Merrimack to Buffalo is to bus and fly which takes 5h 15m and costs $210 - $1,100.
The distance between Merrimack and Buffalo is 387 miles. The road distance is 423 miles.
The best way to get from Merrimack to Buffalo without a car is to bus which takes 12h 36m and costs $140 - $310.
It takes approximately 5h 16m to get from Merrimack to Buffalo, including transfers.
The best way to get from Merrimack to Buffalo is to fly which takes 5h 16m and costs $260 - $1,500. Alternatively, you can bus, which costs $140 - $310 and takes 12h 36m.
Yes, the driving distance between Merrimack to Buffalo is 423 miles. It takes approximately 8h 37m to drive from Merrimack to Buffalo.
There are 237+ hotels available in Buffalo.
What companies run services between Merrimack, NH, USA and Buffalo, NY, USA?
Southwest Airlines, United Airlines, and American Airlines fly from Manchester Airport (MHT) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, you can take a vehicle from Merrimack to Buffalo via North Londonderry NH Transportation Center, Boston - South Station, Boston, and Syracuse Bus Station in around 12h 36m.
- Website
- aa.com
Flights from Manchester Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $240–1,300
Flights from Manchester Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $220–1,300
Flights from Manchester Airport to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $360–1,700
Flights from Manchester Airport to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 7h 1m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $370–1,700
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 47m
- When
- Sunday
- Estimated price
- $140–900
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 3h 59m
- When
- Saturday
- Estimated price
- $190–1,100
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $150–950
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 4h 7m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–950
- Website
- southwest.com
Flights from Manchester Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 11m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,300
Flights from Manchester Airport to Buffalo Niagara International Airport via Chicago Midway
- Ave. Duration
- 7h
- When
- Thursday to Sunday
- Estimated price
- $370–1,700
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 55m
- When
- Monday, Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $180–1,000
- Website
- jetblue.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $140–900
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 3h 50m
- When
- Monday to Thursday
- Estimated price
- $160–950
- Website
- delta.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–950
- Website
- united.com
Flights from Manchester Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $240–1,300
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 4h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 39m
- Frequency
- Once daily
- Estimated price
- $50–170
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $50–120
- Coach Seat short notice purchase
- $60–170
- Business - advance purchase
- $85–360
- Business Class
- $140–390
- Phone
- +1 800 639 3317
- info@concordcoachlines.com
- Website
- concordcoachlines.com
Bus from North Londonderry NH Transportation Center to Boston - South Station
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $9–13
- Website
- https://concordcoachlines.com
Bus from North Londonderry NH Transportation Center to Logan International Airport
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $10–14
- Website
- https://concordcoachlines.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 35m
- Frequency
- Once daily
- Estimated price
- $55–180
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $27–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $55–180
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $27–45
- Website
- https://www.greyhound.com/
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- $25–40
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Phone
- +1 800-639-8080
- contact@bostonexpressbus.com
- Website
- bostonexpressbus.com
Bus from Nashua, NH to Boston South Buses
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $14–21
- Schedules at
- bostonexpressbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Boston, MA to Syracuse, NY
- Ave. Duration
- 6h 25m
- Frequency
- Twice a week
- Estimated price
- $20–90
- Website
- https://www.ourbus.com
Bus from Syracuse, NY to Buffalo, NY
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a week
- Estimated price
- $20–65
- Website
- https://www.ourbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide














