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How to get fromMendrisio to Lyonby train (Trenitalia), train, bus, car, or plane

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There are 6 ways to get from Mendrisio to Lyon by train (Trenitalia), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Mendrisio to Milano Centraletrain train Re80
    2. Take the train from Milano Centrale to Lyon Part Dieutrain train Fr
    6h 42m
    €72–109

  2. Bus

    cheapest
    1. Take the bus from Como to Milanbus bus FlixBus 1524 / ...
    2. Take the bus from Milano, Autostazione Lampugnano to Lyonbus bus 729 / ...
    10h 24m
    €31–120

  3. Train, bus

    1. Take the train from Mendrisio to Malpensa Aeroporto T2train train S50
    2. Take the bus from Milan to Turinbus bus 467 / ...
    3. Take the bus from Turin to Lyonbus bus 480 / ...
    8h 48m
    €34–94

  4. Drive  455.7 km

    1. Drive from Mendrisio to Lyoncar car 455.7 km
    5h
    €82–119

  5. Train to Milano Malpensa Airport, fly

    1. Take the train from Mendrisio to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Lyon–Saint Exupéry Airport (LYS)plane plane MXP - LYS
    4h 54m
    €81–251

  6. Train to Milan Linate Airport, fly

    1. Take the train from Mendrisio to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Lyon–Saint Exupéry Airport (LYS)plane plane LIN - LYS
    7h 50m
    €122–295

Mendrisio to Lyon by train

Calendar28Weekly Trains
Duration6h 42mAverage Duration
Ticket€72Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mendrisio to Lyon.ExpandLaunch map view
  • Distance: 502.7 km
  • Duration: 6h 42m

What companies run services between Mendrisio, Switzerland and Lyon, France?

You can take a train from Mendrisio to Lyon Part Dieu via Milano Centrale in around 6h 42m. Alternatively, you can take a bus from Mendrisio, Autosilo to Lyon via Chiasso, Stazione, Chiasso, Como S. Giovanni, Como, and Milano, Autostazione Lampugnano in around 10h 24m.

Airlines
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