There are 5 ways to get from Melfi to Isernia by bus, train (Trenitalia), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Naples
best- Take the bus from Melfi to Napoli P.zza Garibaldi
- Take the bus from Napoli, Autostazione Metropark to Isernia6
5h 25m€17–34Train
- Take the train from Melfi to Potenza CentraleRe
- Take the train from Potenza Centrale to Napoli CentraleIc
- Take the train from Napoli Centrale to IserniaRe
7h 41m€24–40Drive 180.3 km
- Drive from Melfi to Isernia180.3 km
2h 28m€28–41Bus, train
- Take the bus from Melfi to Napoli P.zza Garibaldi
- Take the train from Napoli Centrale to IserniaRe
5h 33m€21–37Bus
- Take the bus from Melfi to Napoli P.zza Garibaldi
- Take the bus from Napoli P.zza Garibaldi to Isernia433
5h 39m€22–50
Melfi to Isernia by bus and foot
Questions & Answers
The cheapest way to get from Melfi to Isernia is to bus via Naples which costs €16 - €35 and takes 5h 25m.
The fastest way to get from Melfi to Isernia is to drive which takes 2h 28m and costs €27 - €40.
No, there is no direct bus from Melfi to Isernia. However, there are services departing from Melfi and arriving at Isernia via Napoli, Autostazione Metropark. The journey, including transfers, takes approximately 5h 25m.
No, there is no direct train from Melfi to Isernia. However, there are services departing from Melfi and arriving at Isernia via Potenza Centrale and Napoli Centrale. The journey, including transfers, takes approximately 7h 41m.
The distance between Melfi and Isernia is 285 km. The road distance is 180.3 km.
The best way to get from Melfi to Isernia without a car is to bus via Naples which takes 5h 25m and costs €16 - €35.
It takes approximately 5h 25m to get from Melfi to Isernia, including transfers.
Melfi to Isernia bus services, operated by AutoLinee Moretti, depart from Melfi station.
Melfi to Isernia train services, operated by Trenitalia S.p.A., depart from Melfi station.
The best way to get from Melfi to Isernia is to bus via Naples which takes 5h 25m and costs €16 - €35. Alternatively, you can train, which costs €23 - €40 and takes 7h 41m.
What companies run services between Melfi, Italy and Isernia, Italy?
You can take a bus from Melfi to Isernia via Napoli P.zza Garibaldi and Napoli, Autostazione Metropark in around 5h 25m. Alternatively, you can take a train from Melfi to Isernia via Potenza Centrale and Napoli Centrale in around 7h 41m.
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Melfi to Potenza Centrale
- Ave. Duration
- 1h 11m
- Frequency
- Every 4 hours
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
Train from Potenza Centrale to Napoli Centrale
- Ave. Duration
- 2h 21m
- Frequency
- Twice daily
- Estimated price
- €11–20
- Website
- https://www.trenitalia.com/en.html
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 3m
- Frequency
- 4 times a day
- Estimated price
- €8–13
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Potenza Centrale to Napoli Centrale
- Ave. Duration
- 2h 27m
- Frequency
- Twice daily
- Estimated price
- €16–20
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 0972 24590
- booking@autolineemoretti.it
- Website
- autolineemoretti.it
Bus from Melfi to Napoli P.zza Garibaldi
- Ave. Duration
- 2h 30m
- Frequency
- 6 times a week
- Estimated price
- €12–24
- Schedules at
- autolineemoretti.it
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Napoli, Autostazione Metropark to Isernia
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- €4–10
- Schedules at
- satiautobus.com
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Napoli P.zza Garibaldi to Isernia
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €9–26
- Website
- https://www.flixbus.co.uk
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More Questions & Answers
Melfi to Isernia bus services, operated by AutoLinee Moretti, arrive at Napoli P.zza Garibaldi station.
Melfi to Isernia train services, operated by Trenitalia S.p.A., arrive at Potenza Centrale station.
Yes, the driving distance between Melfi to Isernia is 180 km. It takes approximately 2h 28m to drive from Melfi to Isernia.
There are 422+ hotels available in Isernia.










