There are 9 ways to get from Medellín to San Ignacio de Tupile by plane, bus or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.
Recommended option
Fly Medellin Enrique Olaya Herrera to Apartado, travel
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Fly from Medellin Enrique Olaya Herrera (EOH) to Apartado (APO)
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Travel from Apartado to San Ignacio de Tupile
8 alternative options
Fly Medellin Enrique Olaya Herrera to Monteria, travel
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Fly from Medellin Enrique Olaya Herrera (EOH) to Monteria (MTR)
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Travel from Monteria to San Ignacio de Tupile
Fly Medellin Enrique Olaya Herrera to Nuqui, travel
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Fly from Medellin Enrique Olaya Herrera (EOH) to Nuqui (NQU)
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Travel from Nuqui to San Ignacio de Tupile
Fly Medellin Jose Marie Cordova to Monteria, travel
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Fly from Medellin Jose Marie Cordova (MDE) to Monteria (MTR)
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Travel from Monteria to San Ignacio de Tupile
Fly Medellin Jose Marie Cordova to Panama City, bus, travel
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Fly from Medellin Jose Marie Cordova (MDE) to Panama City (PTY)
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Take the bus from Albrook to Agua Fría Número Uno
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Travel from Agua Fría Número Uno to San Ignacio de Tupile
Fly Medellin Jose Marie Cordova to Cartagena, travel
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Fly from Medellin Jose Marie Cordova (MDE) to Cartagena (CTG)
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Travel from Cartagena to San Ignacio de Tupile
Bus, ferry, travel
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Take the bus from Medellín to Turbo
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Take the ferry from Turbo to Sapzurro
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Travel from Sapzurro to Yaviza
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Take the bus from Yaviza to Metetí
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Travel from Metetí to San Ignacio de Tupile
Bus, ferry, travel via Mutatá
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Take the bus from Medellín to Mutatá
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Take the bus from Mutatá to Turbo
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Take the ferry from Turbo to Sapzurro
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Travel from Sapzurro to Yaviza
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Take the bus from Yaviza to Metetí
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Travel from Metetí to San Ignacio de Tupile
Bus, ferry, Tour, travel
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Take the bus from Medellín to Turbo
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Take the ferry from Turbo to Sapzurro
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Take the Tour from Sapzurro to San Blas Islands
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Travel from San Blas Islands to San Ignacio de Tupile
Coronavirus (COVID-19) in Panama
There is widespread community transmission globally.
Some travel restrictions are being lifted in Panama. For the latest travel status, please check the official page for Panama.
For travel planning advice, please refer to our Rome2rio Coronavirus information page .
For the latest travel status, we recommend checking the official page for Panama.
Coronavirus (COVID-19) Travel Advice
Domestic travel is restricted within Panama due to Coronavirus (COVID-19).
Official Coronavirus (COVID-19) Information for PanamaInternational flights leaving Colombia are suspended as part of the response to Coronavirus (COVID-19). Restrictions may also be in place for other modes of transport.
Currently, we are unable to provide international travel restriction information for Panama relating to Coronavirus (COVID-19). For the latest travel status in Panama, please check government recommendations.
Official Coronavirus (COVID-19) Information for PanamaQuestions & Answers
The distance between Medellín and San Ignacio de Tupile is 442 km.
The best way to get from Medellín to San Ignacio de Tupile without a car is to bus and ferry and travel which takes 16h 17m and costs .
It takes approximately 5h 18m to get from Medellín to San Ignacio de Tupile, including transfers.
The quickest flight from Medellin Enrique Olaya Herrera Airport to Apartado Airport is the direct flight which takes 39 min.
Easyfly and Satena offer flights from Medellin Enrique Olaya Herrera Airport to Apartado Airport.
The best way to get from Medellín to Medellin Enrique Olaya Herrera Airport is to taxi which takes 6 min and costs $3 - $4.

- Distance: 442 km
- Duration: 5h 18m
What companies run services between Medellín, Colombia and San Ignacio de Tupile, Panama?
There is no direct connection from Medellín to San Ignacio de Tupile. However, you can take the taxi to Medellin Enrique Olaya Herrera airport, fly to Apartado, then take the travel to San Ignacio de Tupile. Alternatively, you can take the taxi to Medellin Enrique Olaya Herrera airport, fly to Monteria, then take the travel to San Ignacio de Tupile.

- Website
- vivaair.com
Flights from Medellin Jose Marie Cordova to Monteria
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- $35 - $130
Flights from Medellin Jose Marie Cordova to Cartagena
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $20 - $100

- Website
- latam.com
Flights from Medellin Jose Marie Cordova to Monteria
- Ave. Duration
- 53 min
- When
- Every day
- Estimated price
- $30 - $130
Flights from Medellin Jose Marie Cordova to Cartagena
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $30 - $120
Flights from Medellin Jose Marie Cordova to Cartagena via Pereira
- Ave. Duration
- 2h 34m
- When
- Thursday and Friday
- Estimated price
- $30 - $120

- Website
- satena.com
Flights from Medellin Enrique Olaya Herrera to Apartado
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- $45 - $190
Flights from Medellin Enrique Olaya Herrera to Nuqui
- Ave. Duration
- 55 min
- When
- Monday, Wednesday and Friday
- Estimated price
- $70 - $140
Flights from Medellin Enrique Olaya Herrera to Nuqui via Quibdo
- Ave. Duration
- 2h 35m
- When
- Monday and Wednesday
- Estimated price
- $70 - $140

- Website
- easyfly.com.co
Flights from Medellin Enrique Olaya Herrera to Apartado
- Ave. Duration
- 45 min
- When
- Monday, Wednesday, Thursday, Friday, Saturday and Sunday
- Estimated price
- $50 - $190
Flights from Medellin Enrique Olaya Herrera to Monteria
- Ave. Duration
- 1h
- When
- Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday
- Estimated price
- $100 - $180

- Website
- avianca.com
Flights from Medellin Jose Marie Cordova to Monteria
- Ave. Duration
- 53 min
- When
- Every day
- Estimated price
- $30 - $150
Flights from Medellin Jose Marie Cordova to Cartagena
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $30 - $120

- Website
- copaair.com
Flights from Medellin Jose Marie Cordova to Panama City
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $140 - $330
- Phone
- +(507) 314 6291
Bus from Albrook to Agua Fría Número Uno
- Ave. Duration
- 3h 53m
- Frequency
- On demand
- Estimated price
- $7
- Schedules at
- grantnt.com

- Phone
- +57 (4) 4486641
- servicioalcliente@cootransuroccidente.com
- Website
- cootransuroccidente.com
Bus from Medellín to Turbo
- Ave. Duration
- 7h 40m
- Frequency
- Hourly
- Estimated price
- $15 - $20
- Schedules at
- cootransuroccidente.com
Bus from Medellín to Mutatá
- Ave. Duration
- 5h 30m
- Frequency
- Hourly
- Estimated price
- $12 - $16
- Schedules at
- cootransuroccidente.com

- Phone
- +57 (4) 448 77 12
- Website
- gomezhernandez.com
Bus from Medellín to Turbo
- Ave. Duration
- 8h
- Frequency
- Every 2 hours
- Estimated price
- $19
- Schedules at
- transportesgomezhernandez.com
Bus from Medellín to Mutatá
- Ave. Duration
- 6h 5m
- Frequency
- Every 2 hours
- Estimated price
- $19
- Schedules at
- transportesgomezhernandez.com
Bus from Mutatá to Turbo
- Ave. Duration
- 1h 55m
- Frequency
- Every 2 hours
- Schedules at
- transportesgomezhernandez.com
- Phone
- +507 303-3030
Bus from Yaviza to Metetí
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Schedules at
- grantnt.com

- Website
- sotrauraba.com
Bus from Medellín to Mutatá
- Ave. Duration
- 4h 37m
- Frequency
- Hourly
- Estimated price
- $19
- Schedules at
- sotrauraba.com

- Phone
- +57 321 6366022 | +57 321 6366000
- reservas@ecoviajesdarien.com
- Website
- facebook.com
Ferry from Turbo to Sapzurro
- Ave. Duration
- 2h
- Frequency
- Once a week
- Estimated price
- $54
- Schedules at
- ecoviajesdarien.com

- contact@sanblasadventures.com
- Website
- sanblasadventures.com
Ferry from Sapzurro to San Blas Islands
- Ave. Duration
- 3 days 14h
- Frequency
- On demand
- Estimated price
- $465
- Schedules at
- sanblasadventures.com
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