There are 9 ways to get from Mebane to Lexington by bus, plane, car, bus (Flixbus, Greyhound), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Raleigh-Durham International Airport, fly to Louisville International Airport, drive
best- Take the bus from E Washington St at S 5th St to Durham Station Gate J
- Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)RDU - SDF
- Drive from Louisville International Airport (SDF) to Lexington
6h 14m$154–424Drive 403.8 mi
cheapest- Drive from Mebane to Lexington403.8 mi
8h 10m$74–107Bus via Atlanta
- Take the bus from E Washington St at S 5th St to Durham Station Gate JOdx
- Take the bus from Durham to Atlanta Downtown
- Take the bus from Atlanta Bus Station to Lexington Bus Stop
17h 31m$130–280Train, bus
- Take the train from Greensboro to Charlottesville
- Take the train from Charlottesville to Indianapolis
- Take the bus from Indianapolis Union Station to Lexington Bus Stop
26h 30m$206–463Bus to Raleigh-Durham International Airport, fly to Blue Grass Airport
- Take the bus from E Washington St at S 5th St to Durham Station Gate J
- Fly from Raleigh-Durham International Airport (RDU) to Blue Grass Airport (LEX)RDU - LEX
9h 22m$122–805Bus to Piedmont Triad International Airport, fly to Blue Grass Airport
- Take the bus from Mebane Cone Health Park & Ride to Coble Transportation Center
- Fly from Piedmont Triad International Airport (GSO) to Blue Grass Airport (LEX)GSO - LEX
10h 19m$148–908Bus, train to Charlotte Douglas International Airport, fly to Louisville International Airport, drive
- Take the bus from E Washington St at S 5th St to Durham Station Gate J
- Take the train from Durham Amtrak Station to Charlotte Amtrak Station
- Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)CLT - SDF
- Drive from Louisville International Airport (SDF) to Lexington
9h 15m$181–510Bus
- Take the bus from E Washington St at S 5th St to Durham Station Gate JOdx
- Take the bus from Durham to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Lexington Bus Stop
18h 7m$127–277Bus, train
- Take the bus from E Washington St at S 5th St to Durham Station Gate JOdx
- Take the bus from Durham Station Gate G to Union Station - Bus Platform ADrx
- Take the train from Raleigh Union Station to Toledo
- Take the bus from Toledo Bus Stop to Lexington Bus Stop
31h 42m$147–372
Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Mebane to Lexington is to drive which costs $70 - $110 and takes 8h 10m.
The fastest way to get from Mebane to Lexington is to bus and fly and drive which takes 6h 14m and costs $150 - $430.
The distance between Mebane and Lexington is 541 miles. The road distance is 406.2 miles.
The best way to get from Mebane to Lexington without a car is to bus via Atlanta which takes 17h 31m and costs $130 - $280.
It takes approximately 6h 14m to get from Mebane to Lexington, including transfers.
Yes, the driving distance between Mebane to Lexington is 406 miles. It takes approximately 8h 10m to drive from Mebane to Lexington.
There are 136+ hotels available in Lexington.
What companies run services between Mebane, NC, USA and Lexington, KY, USA?
You can take a bus from E Washington St at S 5th St to Lexington via Durham Station Gate J, Durham, Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Lexington Bus Stop in around 17h 31m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 40m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $85–500
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $120–800
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 6h 17m
- When
- Friday
- Estimated price
- $190–1,000
Flights from Piedmont Triad International Airport to Blue Grass Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 29m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $140–900
Flights from Piedmont Triad International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Piedmont Triad International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 7h 22m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $220–1,200
Flights from Charlotte Douglas International Airport to Louisville International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $60–410
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 3h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $100–550
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $160–900
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 4h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–950
Flights from Raleigh-Durham International Airport to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Reagan Washington
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $160–900
Flights from Piedmont Triad International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Charlotte Douglas International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $80–460
- Website
- united.com
Flights from Raleigh-Durham International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Piedmont Triad International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $230–1,200
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 3h 54m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $110–600
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Louisville International Airport
- Ave. Duration
- 1h 32m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $200–310
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Greensboro to Charlottesville
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $60–110
- Website
- https://www.amtrak.com/home.html
Train from Charlottesville to Indianapolis
- Ave. Duration
- 15h 23m
- Frequency
- 3 times a week
- Estimated price
- $55–200
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $55–150
- Coach Seat short notice purchase
- $75–200
- Business - advance purchase
- $100–440
- Business Class
- $170–450
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $31–33
- Website
- https://www.amtrak.com/home.html
Train from Raleigh Union Station to Toledo
- Ave. Duration
- 20h
- Frequency
- Once daily
- Estimated price
- $75–250
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $75–210
- Coach Seat short notice purchase
- $100–250
- Business - advance purchase
- $140–600
- Business Class
- $230–600
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from E Washington St at S 5th St to Durham Station Gate J
- Ave. Duration
- 45 min
- Frequency
- 3 times a day
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
Bus from Durham Station Gate G to Union Station - Bus Platform A
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Durham to Atlanta Downtown
- Ave. Duration
- 6h 45m
- Frequency
- 6 times a week
- Estimated price
- $50–95
- Schedules at
- flixbus.com
Bus from Durham to Atlanta Bus Station
- Ave. Duration
- 7h 30m
- Frequency
- 5 times a day
- Estimated price
- $50–95
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Atlanta Bus Station to Lexington Bus Stop
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $50–150
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://www.greyhound.com/
Bus from Durham to Atlanta Bus Station
- Ave. Duration
- 8h 25m
- Frequency
- 4 times a day
- Estimated price
- $50–85
- Website
- https://www.greyhound.com/
Bus from Toledo Bus Stop to Lexington Bus Stop
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
- Phone
- +1 336-662-0002
- Website
- partnc.org
Bus from Mebane Cone Health Park & Ride to Coble Transportation Center
- Ave. Duration
- 1h 21m
- Frequency
- 4 times a day
- Estimated price
- $2–3
- Schedules at
- partnc.org
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