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How to get fromMebane to Chicagoby bus, plane, bus (Flixbus, Greyhound), train or car

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There are 6 ways to get from Mebane to Chicago by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Raleigh-Durham International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from E Washington St at S 5th St to Durham Station Gate Jbus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)planeRDU - MDW
    5h 55m
    $82–438

  2. Bus to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Mebane Cone Health Park & Ride to Coble Transportation Centerbus
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)planeGSO - ORD
    7h 27m
    $73–371

  3. Bus

    1. Take the bus from E Washington St at S 5th St to Durham Station Gate JbusOdx
    2. Take the bus from Durham to Washington Union Stationbus
    3. Take the bus from Washington Union Station to Chicago Bus Stationbus
    25h 20m
    $110–320

  4. Bus, train

    1. Take the bus from E Washington St at S 5th St to Durham Station Gate JbusOdx
    2. Take the bus from Durham Station Gate G to Union Station - Bus Platform AbusDrx
    3. Take the train from Raleigh Union Station to Chicago Union Stationtrain
    28h 2m
    $170–850

  5. Drive 744.1 mi

    1. Drive from Mebane to Chicagocar744.1 mi
    12h 55m
    $136–197

  6. Bus to Raleigh-Durham International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from E Washington St at S 5th St to Durham Station Gate Jbus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)planeRDU - ORD
    6h 26m
    $87–338

Mebane to Chicago by bus

Calendar14Weekly Buses
Duration25h 20mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

What companies run services between Mebane, NC, USA and Chicago, IL, USA?

You can take a bus from E Washington St at S 5th St to Chicago Bus Station via Durham Station Gate J, Durham, and Washington Union Station in around 25h 20m.

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