What is the cheapest way to get from Mayo Clinic to Springfield?

The cheapest way to get from Mayo Clinic to Springfield is to drive which costs $70 - $110 and takes 7h 47m.

What is the fastest way to get from Mayo Clinic to Springfield?

The fastest way to get from Mayo Clinic to Springfield is to fly which takes 5h 59m and costs $95 - $550.

Is there a direct bus between Mayo Clinic and Springfield?

No, there is no direct bus from Mayo Clinic to Springfield. However, there are services departing from Rochester and arriving at Springfield SMTD Transfer Center via 250 N. Lake St - Madison UW Campus and Chicago Bus Station. The journey, including transfers, takes approximately 14h 28m.

How far is it from Mayo Clinic to Springfield?

The distance between Mayo Clinic and Springfield is 331 miles. The road distance is 398.4 miles.

How do I travel from Mayo Clinic to Springfield without a car?

The best way to get from Mayo Clinic to Springfield without a car is to bus and train via Madison which takes 13h 6m and costs $65 - $220.

How long does it take to get from Mayo Clinic to Springfield?

It takes approximately 5h 59m to get from Mayo Clinic to Springfield, including transfers.

Where do I catch the Mayo Clinic to Springfield bus from?

Mayo Clinic to Springfield bus services, operated by Jefferson Lines, depart from Rochester station.

Bus or fly from Mayo Clinic to Springfield?

The best way to get from Mayo Clinic to Springfield is to fly which takes 5h 59m and costs $95 - $550. Alternatively, you can bus, which costs $70 - $210 and takes 14h 28m.

Where does the Mayo Clinic to Springfield bus arrive?

Mayo Clinic to Springfield bus services, operated by Jefferson Lines, arrive at Madison station.

Can I drive from Mayo Clinic to Springfield?

Yes, the driving distance between Mayo Clinic to Springfield is 398 miles. It takes approximately 7h 47m to drive from Mayo Clinic to Springfield.

Where can I stay near Springfield?

There are 45+ hotels available in Springfield.

Mayo Clinic to Springfield - 6 ways to travel via train, plane, bus, and car

There are 6 ways to get from Mayo Clinic to Springfield by plane, bus, train, car, taxi, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Abraham Lincoln Capital Airport
best
1. Fly from Rochester (RST) to Abraham Lincoln Capital Airport (SPI)RST - SPI
5h 59m
$97–508
Bus, train via Madison
cheapest
1. Take the bus from Rochester to Madison
2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
3. Take the train from Chicago Union Station to Springfield
13h 6m
$66–213
Bus, train
1. Take the bus from Rochester to St. Paul
2. Take the train from St. Paul-Minneapolis to Chicago Union Station
3. Take the train from Chicago Union Station to Springfield
13h 42m
$87–313
Drive 396.1 mi
1. Drive from Mayo Clinic to Springfield396.1 mi
7h 47m
$73–105
Fly to Decatur Airport, taxi
1. Fly from Rochester (RST) to Decatur Airport (DEC)RST - DEC
2. Take the taxi from Decatur Airport (DEC) to Springfield
7h 39m
$168–491
Bus
1. Take the bus from Rochester to Madison
2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
3. Take the bus from Chicago Bus Station to Springfield SMTD Transfer Center
14h 28m
$71–208

Mayo Clinic to Springfield by foot, bus, and train

7Weekly Services

13h 6mAverage Duration

$66Cheapest Price

See schedules

Questions & Answers

Launch map view

Distance: 329.4 mi
Duration: 5h 59m

What companies run services between Mayo Clinic, MN, USA and Springfield, IL, USA?

American Airlines and United Airlines fly from Rochester (RST) to Abraham Lincoln Capital Airport (SPI) 3 times a day. Alternatively, you can take a vehicle from Mayo Clinic to Springfield SMTD Transfer Center via Rochester, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Bus Station in around 14h 28m.

Airlines

Train operators

Bus operators

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