There are 11 ways to get from Mayo Clinic to Spring Arbor by bus, train, car, plane, bus (Greyhound), or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train via Madison
best- Take the bus from Rochester to Madison
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Take the train from Chicago Union Station to Albion Station
13h 43m$101–293Fly Rochester to Kalamazoo-Battle Creek International Airport, train
cheapest- Fly from Rochester (RST) to Kalamazoo-Battle Creek International Airport (AZO)RST - AZO
- Take the train from Kalamazoo to Albion Station
11h 57m$89–459Bus, train
- Take the bus from Rochester to St. Paul
- Take the train from St. Paul-Minneapolis to Chicago Union Station
- Take the train from Chicago Union Station to Albion Station
14h 19m$127–453Drive 547.1 mi
- Drive from Mayo Clinic to Spring Arbor547.1 mi
9h 2m$100–145Fly Rochester to Capital Region International Airport, bus
- Fly from Rochester (RST) to Capital Region International Airport (LAN)RST - LAN
- Take the bus from East Lansing, MI to Jackson, MI
8h 45m$112–533Bus via Chicago
- Take the bus from Rochester to Madison
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Take the bus from Chicago Bus Station to Jackson Bus Stop
15h 42m$101–268Bus
- Take the bus from Rochester to Madison
- Take the bus from Madison to Chicago Bus Station
- Take the bus from Chicago Bus Station to Jackson Bus Stop
15h 56m$108–278Bus to Minneapolis–Saint Paul International Airport, fly to Detroit, train
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Detroit (DTW)MSP - DTW
- Take the train from Dearborn to Jackson Station
7h 20m$154–481Fly Rochester to Chicago O'Hare International Airport, train
- Fly from Rochester (RST) to Chicago O'Hare International Airport (ORD)RST - ORD
- Take the train from Chicago Union Station to Albion Station
8h 20m$98–442Fly Rochester to Gerald R. Ford International Airport, bus
- Fly from Rochester (RST) to Gerald R. Ford International Airport (GRR)RST - GRR
- Take the bus from Grand Rapids, MI to East Lansing, MI
- Take the bus from East Lansing, MI to Jackson, MI
11h 21m$149–734Bus to Minneapolis–Saint Paul International Airport, fly to Gerald R. Ford International Airport, bus
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Gerald R. Ford International Airport (GRR)MSP - GRR
- Take the bus from Grand Rapids, MI to East Lansing, MI
- Take the bus from East Lansing, MI to Jackson, MI
10h 5m$192–866
Rochester (RST) to Capital Region International Airport (LAN) flights
Questions & Answers
The cheapest way to get from Mayo Clinic to Spring Arbor is to drive which costs $100 - $150 and takes 9h 2m.
The fastest way to get from Mayo Clinic to Spring Arbor is to bus and fly and train which takes 7h 20m and costs $150 - $490.
The distance between Mayo Clinic and Spring Arbor is 575 miles. The road distance is 550.3 miles.
The best way to get from Mayo Clinic to Spring Arbor without a car is to bus and train via Madison which takes 13h 43m and costs $100 - $300.
It takes approximately 13h 43m to get from Mayo Clinic to Spring Arbor, including transfers.
Yes, the driving distance between Mayo Clinic to Spring Arbor is 550 miles. It takes approximately 9h 2m to drive from Mayo Clinic to Spring Arbor.
There are 29+ hotels available in Spring Arbor.
What companies run services between Mayo Clinic, MN, USA and Spring Arbor, MI, USA?
You can take a vehicle from Mayo Clinic to Spring Arbor via Rochester, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, Chicago Bus Station, and Jackson Bus Stop in around 15h 42m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- delta.com
Flights from Rochester to Kalamazoo-Battle Creek International Airport via Minneapolis–Saint Paul International Airport, Detroit
- Ave. Duration
- 9h 42m
- When
- Every day
- Estimated price
- $70–370
Flights from Minneapolis–Saint Paul International Airport to Detroit
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $70–410
Flights from Minneapolis–Saint Paul International Airport to Detroit via Milwaukee
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $70–410
Flights from Minneapolis–Saint Paul International Airport to Detroit via Green Bay
- Ave. Duration
- 3h 54m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $70–410
Flights from Rochester to Gerald R. Ford International Airport via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $100–650
Flights from Minneapolis–Saint Paul International Airport to Gerald R. Ford International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $120–750
Flights from Minneapolis–Saint Paul International Airport to Gerald R. Ford International Airport via Detroit
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $150–850
- Website
- aa.com
Flights from Rochester to Capital Region International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 26m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $70–430
Flights from Rochester to Kalamazoo-Battle Creek International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 7h 48m
- When
- Every day
- Estimated price
- $50–320
Flights from Rochester to Kalamazoo-Battle Creek International Airport via Minneapolis–Saint Paul International Airport, Chicago O'Hare International Airport
- Ave. Duration
- 7h 43m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $55–340
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $35–240
Flights from Rochester to Gerald R. Ford International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 43m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $95–600
Flights from Minneapolis–Saint Paul International Airport to Gerald R. Ford International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 42m
- When
- Thursday
- Estimated price
- $130–800
- Website
- southwest.com
Flights from Minneapolis–Saint Paul International Airport to Detroit via Chicago Midway
- Ave. Duration
- 3h 50m
- When
- Monday to Friday
- Estimated price
- $75–420
Flights from Minneapolis–Saint Paul International Airport to Gerald R. Ford International Airport via Chicago Midway
- Ave. Duration
- 3h 35m
- When
- Sunday
- Estimated price
- $130–800
- Website
- suncountry.com
Flights from Minneapolis–Saint Paul International Airport to Detroit
- Ave. Duration
- 1h 45m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- $70–410
Flights from Minneapolis–Saint Paul International Airport to Gerald R. Ford International Airport
- Ave. Duration
- 1h 21m
- When
- Friday
- Estimated price
- $120–750
- Website
- united.com
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $35–240
Flights from Rochester to Gerald R. Ford International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $95–600
Flights from Minneapolis–Saint Paul International Airport to Gerald R. Ford International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $130–800
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Albion Station
- Ave. Duration
- 3h 13m
- Frequency
- Once daily
- Estimated price
- $30–120
- Website
- https://www.amtrak.com/home.html
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 24m
- Frequency
- 3 times a day
- Estimated price
- $60–240
- Website
- https://www.amtrak.com/home.html
Train from Kalamazoo to Albion Station
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $6–60
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $14–26
- Coach Seat short notice purchase
- $6–60
- Business - advance purchase
- $8–75
- Business Class
- $14–160
Train from Dearborn to Jackson Station
- Ave. Duration
- 1h 5m
- Frequency
- 3 times a day
- Estimated price
- $8–60
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $17–28
- Coach Seat short notice purchase
- $8–60
- Business - advance purchase
- $11–85
- Business Class
- $19–170
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $20–95
- Book at
- https://www.jeffersonlines.com
Bus from Rochester to St. Paul
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–55
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 608-752-5407
- vangalder@coachusa.com
- Website
- coachusa.com
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $21–40
- Website
- https://www.coachusa.com/van-galder-bus-company
- Phone
- +1 989-725-5105
- Website
- indiantrails.com
Bus from East Lansing, MI to Jackson, MI
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $7–22
- Website
- https://indiantrails.com
Bus from Grand Rapids, MI to East Lansing, MI
- Ave. Duration
- 1h 20m
- Frequency
- Twice daily
- Estimated price
- $12–30
- Website
- https://indiantrails.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Jackson Bus Stop
- Ave. Duration
- 5h 10m
- Frequency
- 5 times a week
- Estimated price
- $30–95
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Madison to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $28–50
- Schedules at
- flixbus.com
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $19–45
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
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