There are 8 ways to get from Mayo Clinic to Decatur by bus (Flixbus), bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Rochester to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Bus Station to Decatur Downtown Transportation Centerbus
13h 46m$108–179Fly Rochester to Decatur Airport
cheapest- Fly from Rochester (RST) to Decatur Airport (DEC)plane RST - DEC
6h 22m$70–394Bus, train
- Take the bus from Rochester to St. Paulbus
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Centerbus
15h 36m$326–510Drive 404.1 mi
- Drive from Mayo Clinic to Decaturcar 404.1 mi
8h 10m$74–107Fly Rochester to Abraham Lincoln Capital Airport, bus
- Fly from Rochester (RST) to Abraham Lincoln Capital Airport (SPI)plane RST - SPI
- Take the bus from Springfield SMTD Transfer Center to Decatur Downtown Transportation Centerbus
10h 38m$75–414Bus, train via Milwaukee
- Take the bus from Rochester to Milwaukeebus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Centerbus
13h 48m$192–292Fly Rochester to University Of Illinois Willard Airport, bus
- Fly from Rochester (RST) to University Of Illinois Willard Airport (CMI)plane RST - CMI
- Take the bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Centerbus
7h 27m$81–411Bus to Minneapolis–Saint Paul International Airport, fly to Lambert–St. Louis International Airport, bus
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane MSP - STL
- Take the bus from St Louis Bus Station to Decatur Downtown Transportation Centerbus
8h 8m$454–1,038
Mayo Clinic to Decatur by foot and bus
Comparing Your Travel Options
The cheapest way to get from Mayo Clinic to Decatur is to drive which costs $70 - $110 and takes 8h 10m.
The fastest way to get from Mayo Clinic to Decatur is to fly which takes 6h 22m and costs $70 - $400.
No, there is no direct bus from Mayo Clinic to Decatur. However, there are services departing from Rochester and arriving at Decatur Downtown Transportation Center via 250 N. Lake St - Madison UW Campus and Chicago Bus Station. The journey, including transfers, takes approximately 13h 46m.
The distance between Mayo Clinic and Decatur is 544 miles. The road distance is 406.5 miles.
The best way to get from Mayo Clinic to Decatur without a car is to bus which takes 13h 46m and costs $100 - $180.
It takes approximately 13h 46m to get from Mayo Clinic to Decatur, including transfers.
Mayo Clinic to Decatur bus services, operated by Jefferson Lines, depart from Rochester station.
The best way to get from Mayo Clinic to Decatur is to bus which takes 13h 46m and costs $100 - $180. Alternatively, you can fly, which costs $70 - $400 and takes 6h 22m.
Mayo Clinic to Decatur bus services, operated by Jefferson Lines, arrive at Madison station.
Yes, the driving distance between Mayo Clinic to Decatur is 407 miles. It takes approximately 8h 10m to drive from Mayo Clinic to Decatur.
What companies run services between Mayo Clinic, MN, USA and Decatur, IL, USA?
You can take a vehicle from Mayo Clinic to Decatur Downtown Transportation Center via Rochester, Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Bus Station in around 13h 46m. Alternatively, American Airlines and United Airlines fly from Rochester (RST) to Decatur Airport (DEC) once daily.
- Website
- aa.com
Flights from Rochester to Abraham Lincoln Capital Airport via Chicago O'Hare
- Ave. Duration
- 8h 43m
- When
- Every day
- Estimated price
- $55–350
Flights from Rochester to University Of Illinois Willard Airport via Chicago O'Hare
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $55–340
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $95–600
- Website
- southwest.com
Flights from Minneapolis–Saint Paul International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $95–600
Flights from Minneapolis–Saint Paul International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 35m
- When
- Tuesday to Friday
- Estimated price
- $110–650
- Website
- united.com
Flights from Rochester to Decatur Airport via Chicago O'Hare
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $55–340
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 32m
- Frequency
- 3 times a day
- Estimated price
- $220–350
- Website
- Amtrak
Train from Chicago Union Station to Champaign-Urbana
- Ave. Duration
- 2h 31m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to Champaign-Urbana
- Ave. Duration
- 2h 31m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Rochester to St. Paul
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Bus from Rochester to Milwaukee
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
- Phone
- +1 (866) 912 - 6224
- questions@coachusa.com
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Decatur Downtown Transportation Center
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a week
- Estimated price
- $28–45
- Schedules at
- Flixbus USA
Bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Center
- Ave. Duration
- 55 min
- Frequency
- 5 times a week
- Estimated price
- $7–11
- Schedules at
- Flixbus USA
Bus from Springfield SMTD Transfer Center to Decatur Downtown Transportation Center
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $5–9
- Schedules at
- Flixbus USA
Bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Center
- Ave. Duration
- 55 min
- Frequency
- 5 times a week
- Estimated price
- $7–11
- Schedules at
- Flixbus USA
Bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Center
- Ave. Duration
- 55 min
- Frequency
- 5 times a week
- Estimated price
- $7–11
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Decatur Downtown Transportation Center
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
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Booking & Getting There
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