There are 8 ways to get from Mayo Clinic to Appleton by plane, bus, taxi, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Rochester to Appleton International Airport
best- Fly from Rochester (RST) to Appleton International Airport (ATW)plane RST - ATW
5h 21m$65–370Drive 233.6 mi
cheapest- Drive from Mayo Clinic to Appletoncar 233.6 mi
4h 31m$43–62Bus, taxi
- Take the bus from Rochester to St. Paulbus
- Take the bus from St. Paul-Minneapolis to Green Bay Amtrak Stationbus
- Take the taxi from Green Bay Amtrak Station to Appletontaxi
9h 4mFly Rochester to Green Bay, taxi
- Fly from Rochester (RST) to Green Bay (GRB)plane RST - GRB
- Take the taxi from Green Bay (GRB) to Appletontaxi
5h 55m$146–467Bus to Minneapolis–Saint Paul International Airport, fly to Appleton International Airport
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Appleton International Airport (ATW)plane MSP - ATW
3h 55m$88–422Bus to Minneapolis–Saint Paul International Airport, fly to Green Bay, taxi
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Green Bay (GRB)plane MSP - GRB
- Take the taxi from Green Bay (GRB) to Appletontaxi
4h 19m$174–519Bus to Minneapolis–Saint Paul International Airport, fly to Central Wisconsin Airport, drive
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Central Wisconsin Airport (CWA)plane MSP - CWA
- Drive from Central Wisconsin Airport (CWA) to Appletoncar
5h 16m$79–402Bus, taxi via Madison
- Take the bus from Rochester to Madisonbus
- Take the bus from Madison to Green Bay Transit, WIbus 106
- Take the taxi from Green Bay Transit, WI to Appletontaxi
10h 4m$170–338
Rochester (RST) to Appleton International Airport (ATW) flights
Questions & Answers
The cheapest way to get from Mayo Clinic to Appleton is to drive which costs $40 - $65 and takes 4h 31m.
The fastest way to get from Mayo Clinic to Appleton is to bus and fly which takes 3h 55m and costs $85 - $430.
The distance between Mayo Clinic and Appleton is 214 miles. The road distance is 235 miles.
The best way to get from Mayo Clinic to Appleton without a car is to bus and taxi which takes 9h 4m and costs .
It takes approximately 5h 21m to get from Mayo Clinic to Appleton, including transfers.
Yes, the driving distance between Mayo Clinic to Appleton is 235 miles. It takes approximately 4h 31m to drive from Mayo Clinic to Appleton.
There are 79+ hotels available in Appleton.
What companies run services between Mayo Clinic, MN, USA and Appleton, WI, USA?
American Airlines, Delta, and United Airlines fly from Rochester (RST) to Appleton International Airport (ATW) every 3 hours.
- Website
- delta.com
Flights from Rochester to Appleton International Airport via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $45–310
Flights from Rochester to Green Bay via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $45–310
Flights from Minneapolis–Saint Paul International Airport to Appleton International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $50–380
Flights from Minneapolis–Saint Paul International Airport to Green Bay
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $55–380
Flights from Minneapolis–Saint Paul International Airport to Central Wisconsin Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $45–360
- Website
- aa.com
Flights from Rochester to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $50–330
Flights from Rochester to Green Bay via Chicago O'Hare
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $50–340
- Website
- united.com
Flights from Rochester to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $50–330
Flights from Rochester to Green Bay via Chicago O'Hare
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $50–340
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to St. Paul
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–55
- Book at
- https://www.jeffersonlines.com
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $20–95
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from St. Paul-Minneapolis to Green Bay Amtrak Station
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $19–45
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
- Phone
- +1 800-236-1240
- Website
- golamers.com
Bus from Madison to Green Bay Transit, WI
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $30–95
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
- Ave. Duration
- 38 min
- Estimated price
- $100–150
Yellow Cab Green Bay
- Phone
- +1-920-435-1111
- Website
- yellowcabgreenbay.com
Yellow Cab Green Bay
- Phone
- +1-920-435-1111
- Website
- yellowcabgreenbay.com
Yellow Cab Green Bay
- Phone
- +1-920-435-1111
- Website
- yellowcabgreenbay.com
Yellow Cab Green Bay
- Phone
- +1-920-435-1111
- Website
- yellowcabgreenbay.com
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