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How to get fromMayo Clinic to Appletonby plane, bus, taxi or car

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There are 8 ways to get from Mayo Clinic to Appleton by plane, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Appleton International Airport

    best
    1. Fly from Rochester (RST) to Appleton International Airport (ATW)planeRST - ATW
    5h 24m
    $65–360

  2. Drive 233.2 mi

    cheapest
    1. Drive from Mayo Clinic to Appletoncar233.2 mi
    4h 29m
    $43–62

  3. Bus, taxi

    1. Take the bus from Rochester to St. Paulbus
    2. Take the bus from St. Paul-Minneapolis to Green Bay Amtrak Stationbus
    3. Take the taxi from Green Bay Amtrak Station to Appletontaxi
    9h 4m

  4. Fly Rochester to Green Bay, taxi

    1. Fly from Rochester (RST) to Green Bay (GRB)planeRST - GRB
    2. Take the taxi from Green Bay (GRB) to Appletontaxi
    6h
    $146–457

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Appleton International Airport

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Appleton International Airport (ATW)planeMSP - ATW
    3h 53m
    $93–402

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Green Bay, taxi

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Green Bay (GRB)planeMSP - GRB
    3. Take the taxi from Green Bay (GRB) to Appletontaxi
    4h 21m
    $174–499

  7. Bus to Minneapolis–Saint Paul International Airport, fly to Central Wisconsin Airport, drive

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Central Wisconsin Airport (CWA)planeMSP - CWA
    3. Drive from Central Wisconsin Airport (CWA) to Appletoncar
    5h 21m
    $84–382

  8. Bus, taxi via Madison

    1. Take the bus from Rochester to Madisonbus
    2. Take the bus from Madison to Green Bay Transit, WIbus106
    3. Take the taxi from Green Bay Transit, WI to Appletontaxi
    10h 4m
    $170–338

Rochester (RST) to Appleton International Airport (ATW) flights

Calendar38Weekly Planes
Duration4h 54mAverage Duration
Ticket$47Cheapest Price
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Questions & Answers

What companies run services between Mayo Clinic, MN, USA and Appleton, WI, USA?

United Airlines, Delta, and American Airlines fly from Rochester (RST) to Appleton International Airport (ATW) 5 times a day.

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