Rome2Rio

How to get fromMattoon to Destinby train, bus, plane, taxi, or car

Find Transport to Destin

See all options

There are 8 ways to get from Mattoon to Destin by train, bus, plane, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus to Lambert–St. Louis International Airport, fly to Destin–Fort Walton Beach Airport

    best
    1. Take the train from Mattoon Amtrak Station to Carbondaletrain train
    2. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    9h 6m
    $185–692

  2. Drive 730.1 mi

    cheapest
    1. Drive from Mattoon to Destincar car 730.1 mi
    13h 20m
    $134–193

  3. Train, bus, taxi via New Orleans

    1. Take the train from Mattoon Amtrak Station to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    3. Take the bus from Gulfport to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    22h 53m
    $379–687

  4. Train, bus, taxi

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Montgomery Intermodal Centerbus bus
    4. Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus bus
    5. Take the bus from Mobile to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    27h 1m
    $277–477

  5. Train, bus to Midamerica St. Louis Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the train from Mattoon Amtrak Station to Carbondaletrain train
    2. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    3. Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane plane BLV - VPS
    9h 22m
    $183–580

  6. Train, bus to Lambert–St. Louis International Airport, fly to Northwest Florida Beaches International Airport, taxi

    1. Take the train from Mattoon Amtrak Station to Carbondaletrain train
    2. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    4. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    9h 45m
    $265–837

  7. Train, bus to Lambert–St. Louis International Airport, fly to Pensacola International Airport, taxi

    1. Take the train from Mattoon Amtrak Station to Carbondaletrain train
    2. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS)plane plane STL - PNS
    4. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    9h 53m
    $265–847

  8. Train, bus, bus to Peoria International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Springfield SMTD Transfer Centerbus bus
    3. Take the bus from Springfield to Peoria Amtrak Stationbus bus
    4. Fly from Peoria International Airport (PIA) to Destin–Fort Walton Beach Airport (VPS)plane plane PIA - VPS
    10h 29m
    $165–544

Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar33Weekly Planes
Duration3h 6mAverage Duration
Ticket$91Cheapest Price
See schedules

Questions & Answers

What companies run services between Mattoon, IL, USA and Destin, FL, USA?

There is no direct connection from Mattoon to Destin. However, you can take the train to Carbondale, walk to Carbondale Intermodal Station, take the bus to St Louis Bus Station, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Destin–Fort Walton Beach Airport (VPS), then take the taxi to Destin. Alternatively, you can take the train to New Orleans Union Passenger Terminal, take the train to Gulfport Amtrak Sta, walk to Gulfport, take the bus to Crestview, then take the taxi to Destin.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Mattoon

Trips to Destin

Popular routes