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How to get fromMattoon to Buffaloby train, plane, train (Amtrak), bus, or car

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There are 8 ways to get from Mattoon to Buffalo by train, plane, train (Amtrak), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to University Of Illinois Willard Airport, fly

    best
    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Fly from University Of Illinois Willard Airport (CMI) to Buffalo Niagara International Airport (BUF)plane plane CMI - BUF
    7h 11m
    $148–738

  2. Drive  625.2 mi

    cheapest
    1. Drive from Mattoon to Buffalocar car 625.2 mi
    11h 20m
    $115–165

  3. Train (Amtrak)

    1. Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain train Saluki / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    16h 11m
    $387–736

  4. Train, bus

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Chicago Bus Stationbus bus
    3. Take the bus from Chicago to Clevelandbus bus
    4. Take the bus from Cleveland to Buffalobus bus
    16h 21m
    $118–238

  5. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Mattoon Amtrak Station to Homewoodtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    8h 42m
    $263–465

  6. Train to Chicago Midway International Airport, fly

    1. Take the train from Mattoon Amtrak Station to Homewoodtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    8h 20m
    $253–475

  7. Train, bus to Decatur Airport, fly

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Centerbus bus
    3. Fly from Decatur Airport (DEC) to Buffalo Niagara International Airport (BUF)plane plane DEC - BUF
    12h 1m
    $161–745

  8. Train, bus via Brook Park

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus bus
    4. Take the bus from Cleveland Bus Station to Buffalobus bus
    16h 56m
    $165–248

Mattoon to Buffalo by train (Amtrak)

Calendar14Weekly Trains
Duration16h 11mAverage Duration
Ticket$387Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mattoon to Buffalo.ExpandLaunch map view
  • Distance: 592.3 mi
  • Duration: 7h 11m

What companies run services between Mattoon, IL, USA and Buffalo, NY, USA?

You can take a train from Mattoon Amtrak Station to Buffalo via Chicago Union Station and Buffalo Depew Station in around 16h 11m.

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