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How to get fromMatlacha to Key Westby ferry, bus (Flixbus, Greyhound), car, bus or plane

Find Transport to Key West

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There are 6 ways to get from Matlacha to Key West by ferry, bus (Flixbus, Greyhound), car, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry

    best
    1. Take the ferry from Fort Myers Beach, FL to Key West, FLferryFort Myers Beach
    4h 35m
    $179–188

  2. Drive 284.9 mi

    cheapest
    1. Drive from Matlacha to Key Westcar284.9 mi
    6h 15m
    $52–76

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus
    2. Take the bus from Miami Airport Station to Big Pine Keybus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    10h 18m
    $80–131

  4. Bus to Miami International Airport, fly

    1. Take the bus from Fort Myers 7-11 to Miami Airportbus
    2. Fly from Miami International Airport (MIA) to Key West International Airport (EYW)planeMIA - EYW
    5h 27m
    $219–581

  5. Bus to Tampa, fly

    1. Take the bus from Fort Myers 7-11 to Tampa International Airportbus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)planeTPA - EYW
    5h 9m
    $166–626

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Key West International Airport (EYW)planeFLL - EYW
    4h 37m
    $123–500

Miami International Airport (MIA) to Key West International Airport (EYW) flights

Calendar44Weekly Planes
Duration1h 9mAverage Duration
Ticket$36Cheapest Price
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Questions & Answers

What companies run services between Matlacha, FL, USA and Key West, FL, USA?

Key West Express operates a ferry from Fort Myers Beach, FL to Key West, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a vehicle from Matlacha to N Roosevelt & 3rd Street via Fort Myers Bus Stop, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 10h 18m.

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