There are 7 ways to get from Matanzas to Cayo Guillermo by train, taxi, bus, car or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.
Recommended
Train, taxi
-
Take the train from Matanzas to Ciego de Ávila
-
Take a taxi from Morón to Cayo Guillermo
Bus, taxi
-
Take the bus from Matanzas to Sancti Spíritus
-
Take the bus from Sancti Spíritus to Ciego de Avila
-
Take a taxi from Morón to Cayo Guillermo
Bus, taxi via Santa Clara
-
Take the bus from Matanzas to Santa Clara
-
Take the bus from Santa Clara to Morón
-
Take a taxi from Morón to Cayo Guillermo
Drive
-
Drive from Matanzas to Cayo Guillermo
Fly Varadero to Santa Clara, drive
-
Fly from Varadero (VRA) to Santa Clara (SNU)
-
Drive from Santa Clara to Cayo Guillermo
Train to Havana, fly to Santa Clara, drive
-
Take the train from Matanzas to Havana - La Coubre
-
Fly from Havana (HAV) to Santa Clara (SNU)
-
Drive from Santa Clara to Cayo Guillermo
Fly Varadero to Camaguey, train, taxi
-
Fly from Varadero (VRA) to Camaguey (CMW)
-
Take the train from Camaguey to Ciego de Ávila
-
Take a taxi from Morón to Cayo Guillermo
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Questions & Answers
The cheapest way to get from Matanzas to Cayo Guillermo is to drive which costs $55 - $85 and takes 6h 40m.
The quickest way to get from Matanzas to Cayo Guillermo is to drive which costs $55 - $85 and takes 6h 40m.
It is 303 km from Matanzas to Cayo Guillermo. It is approximately 495.8 km to drive.
The best way to get from Matanzas to Cayo Guillermo without a car is to train and taxi which takes 9h 54m and costs $65 - $85.
It takes approximately 9h 54m to get from Matanzas to Cayo Guillermo, including transfers.
There is no direct flight from Varadero Airport to Santa Clara Airport. The quickest flight takes 3h 30m and has one stopover.
Yes, the driving distance between Matanzas to Cayo Guillermo is 496 km. It takes approximately 6h 40m to drive from Matanzas to Cayo Guillermo.
American Airlines offers flights from Varadero Airport to Santa Clara Airport.
The best way to get from Matanzas to Varadero Airport is to bus which takes 35 min and costs $2 - $4.

- Distance: 302.9 km
- Duration: 9h 54m
What companies run services between Matanzas, Cuba and Cayo Guillermo, Cuba?
There is no direct connection from Matanzas to Cayo Guillermo. However, you can take the train to Ciego de Ávila, take the walk to Ciego de Ávila, take the bus to Morón, then take the taxi to Cayo Guillermo. Alternatively, you can take the bus to Sancti Spíritus, take the bus to Ciego de Avila, take the bus to Ciego de Ávila, take the bus to Morón, then take the taxi to Cayo Guillermo.

- Website
- aa.com
Flights from Varadero to Santa Clara via Miami
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $380 - $1,500
Flights from Havana to Santa Clara via Miami
- Ave. Duration
- 8h 2m
- When
- Every day
- Estimated price
- $290 - $1,100
Flights from Varadero to Camaguey via Miami
- Ave. Duration
- 18h 35m
- When
- Every day
- Estimated price
- $550 - $2,100

- Website
- vivaaerobus.com
Flights from Havana to Santa Clara via Cancun
- Ave. Duration
- 10h 55m
- When
- Tuesday
- Estimated price
- $130 - $600
Flights from Varadero to Camaguey via Miami, Cancun
- Ave. Duration
- 17h 35m
- When
- Monday and Friday
- Estimated price
- $280 - $1,400

- Website
- en.wikipedia.org
Train from Matanzas to Ciego de Ávila
- Ave. Duration
- 6h 51m
- Frequency
- 6 times a week
- Estimated price
- $1 - $2
- Schedules at
- thebusschedule.com
- Old trains
- $1
- Second class
- $1 - $2
- First class
- $1 - $2
Train from Matanzas to Havana - La Coubre
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $1
- Schedules at
- thebusschedule.com
- Old trains
- $1
- Second class
- $1
- First class
- $1
Train from Camaguey to Ciego de Ávila
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- thebusschedule.com
- Old trains
- $1
- Second class
- $1
- First class
- $1

- Phone
- +53 7873 7373
- Website
- facebook.com
Bus from Matanzas to Sancti Spíritus
- Ave. Duration
- 4h
- Frequency
- Twice a week
- Schedules at
- facebook.com
Bus from Santa Clara to Morón
- Ave. Duration
- 3h
- Frequency
- 3 times a week
- Schedules at
- facebook.com

- Phone
- +53 59 89 0616
- viazul@eon.cu
- Website
- viazul.wetransp.com
Bus from Sancti Spíritus to Ciego de Avila
- Ave. Duration
- 1h 25m
- Frequency
- Every 2 hours
- Estimated price
- $4 - $7
- Schedules at
- viazul.wetransp.com
Bus from Matanzas to Santa Clara
- Ave. Duration
- 5h 15m
- Frequency
- 5 times a day
- Estimated price
- $13 - $20
- Schedules at
- viazul.wetransp.com
- Ave. Duration
- 1h 22m
- Estimated price
- $65 - $80
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