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How to get fromMatamoros to Key Westby plane, bus, ferry or car

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There are 8 ways to get from Matamoros to Key West by plane, bus, ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Brownsville-South Padre Island International Airport

    best
    1. Fly from Brownsville-South Padre Island International Airport (BRO) to Key West International Airport (EYW)planeBRO - EYW
    9h 43m
    $143–615

  2. Bus, ferry

    1. Take the bus from Brownsville Bus Station to Houston - Harrisburg Blvdbus
    2. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus
    3. Take the ferry from Fort Myers Beach, FL to Key West, FLferry
    33h 38m
    $395–479

  3. Drive 1,679.5 mi

    1. Drive from Matamoros to Key Westcar1,679.5 mi
    29h 49m
    $307–443

  4. Bus to Mcallen Miller International Airport, fly

    1. Take the bus from Brownsville to McAllen Central Stationbus
    2. Fly from Mcallen Miller International Airport (MFE) to Key West International Airport (EYW)planeMFE - EYW
    6h 40m
    $148–724

  5. Bus to Rio Grande Valley International Airport, fly

    1. Take the bus from Brownsville to Harlingen Bus Stationbus
    2. Fly from Rio Grande Valley International Airport (HRL) to Key West International Airport (EYW)planeHRL - EYW
    8h 18m
    $163–615

  6. Bus to Corpus Christi International Airport, fly

    1. Take the bus from Brownsville Bus Station to Robstown Stationbus
    2. Fly from Corpus Christi International Airport (CRP) to Key West International Airport (EYW)planeCRP - EYW
    8h 35m
    $193–608

  7. Bus, ferry via Matamoros(Hotel Los Lirios)

    1. Take the bus from Matamoros(Hotel Los Lirios) to Houston Bus Stationbus
    2. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus
    3. Take the ferry from Fort Myers Beach, FL to Key West, FLferry
    37h 38m
    $368–480

  8. Bus, ferry via Arcadia

    1. Take the bus from Matamoros to Houstonbus
    2. Take the bus from Houston to Billar El Mexicano - Arcadiabus
    3. Take the bus from Arcadia to Fort Myersbus
    4. Take the ferry from Fort Myers Beach, FL to Key West, FLferry
    37h 48m
    $430–610

Brownsville-South Padre Island International Airport (BRO) to Key West International Airport (EYW) flights

Calendar14Weekly Planes
Duration8h 59mAverage Duration
Ticket$130Cheapest Price
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Questions & Answers

What companies run services between Matamoros, Tamaulipas, Mexico and Key West, FL, USA?

United Airlines and American Airlines fly from Brownsville-South Padre Island International Airport (BRO) to Key West International Airport (EYW) twice daily.

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