There are 8 ways to get from Mashpee to Buffalo by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Barnstable Municipal Airport to Buffalo Niagara International Airport
best- Fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF)plane HYA - BUF
6h 56m$441–1,695Drive 507.4 mi
cheapest- Drive from Mashpee to Buffalocar 507.4 mi
8h 58m$93–134Bus
- Take the bus from Bourne to Boston South Stationbus
- Take the bus from Boston to Syracuse Bus Stationbus
- Take the bus from Syracuse Bus Station to Buffalobus
12h 50m$142–281Bus, train
- Take the bus from Park & Ride, Exit 1A/B - Jct. US 6 to Boston South Busesbus Hyannis - South Shore to Logan Airport
- Take the train from Boston to Buffalo Depew Stationtrain Lake Shore Limited
15h 54m$201–360Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport
- Take the bus from Bourne to Boston Airportbus
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
5h 36m$234–1,059Drive to Provincetown Municipal Airport, fly to Buffalo Niagara International Airport
- Drive from Mashpee to Provincetown Municipal Airport (PVC)car
- Fly from Provincetown Municipal Airport (PVC) to Buffalo Niagara International Airport (BUF)plane PVC - BUF
6h 48m$156–994Bus to Boston Logan Airport, fly to Rochester, bus
- Take the bus from Bourne to Boston Airportbus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 45m$315–825Bus via New York
- Take the bus from Bourne to Providence Bus Terminalbus
- Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus
- Take the bus from New York to Buffalobus
16h 56m$113–393
Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF) flights
Questions & Answers
The cheapest way to get from Mashpee to Buffalo is to drive which costs $90 - $140 and takes 8h 58m.
The fastest way to get from Mashpee to Buffalo is to bus and fly which takes 5h 36m and costs $230 - $1,100.
The distance between Mashpee and Buffalo is 464 miles. The road distance is 510.4 miles.
The best way to get from Mashpee to Buffalo without a car is to bus which takes 12h 50m and costs $140 - $290.
It takes approximately 6h 56m to get from Mashpee to Buffalo, including transfers.
The best way to get from Mashpee to Buffalo is to fly which takes 6h 56m and costs $440 - $1,700. Alternatively, you can bus, which costs $140 - $290 and takes 12h 50m.
Yes, the driving distance between Mashpee to Buffalo is 510 miles. It takes approximately 8h 58m to drive from Mashpee to Buffalo.
There are 244+ hotels available in Buffalo.
What companies run services between Mashpee, MA, USA and Buffalo, NY, USA?
American Airlines, Cape Air, and JetBlue Airways fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a vehicle from Mashpee to Buffalo via Bourne, Boston South Station, Boston, and Syracuse Bus Station in around 12h 50m.
- Website
- aa.com
Flights from Barnstable Municipal Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 5h 24m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $270–1,500
Flights from Barnstable Municipal Airport to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 7h 29m
- When
- Saturday
- Estimated price
- $420–2,000
Flights from Barnstable Municipal Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 9h 26m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,400
Flights from Barnstable Municipal Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 10h 3m
- When
- Every day
- Estimated price
- $240–1,400
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $140–900
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 3h 56m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–1,000
Flights from Provincetown Municipal Airport to Buffalo Niagara International Airport via Boston Logan Airport
- Ave. Duration
- 4h 47m
- When
- Sunday
- Estimated price
- $140–950
Flights from Provincetown Municipal Airport to Buffalo Niagara International Airport via Boston Logan Airport, New York La Guardia
- Ave. Duration
- 6h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–1,000
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $75–500
Flights from Boston Logan Airport to Rochester via Philadelphia
- Ave. Duration
- 4h 4m
- When
- Sunday
- Estimated price
- $95–600
- Website
- jetblue.com
Flights from Barnstable Municipal Airport to Buffalo Niagara International Airport via Boston Logan Airport
- Ave. Duration
- 7h 28m
- When
- Every day
- Estimated price
- $210–1,400
Flights from Barnstable Municipal Airport to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 7h 58m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $220–1,400
Flights from Barnstable Municipal Airport to Buffalo Niagara International Airport via Nantucket, Boston Logan Airport
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $220–1,400
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $140–900
Flights from Provincetown Municipal Airport to Buffalo Niagara International Airport via Boston Logan Airport
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $140–950
- Website
- delta.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–950
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 4h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–550
Flights from Boston Logan Airport to Rochester via New York JFK
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $85–550
- Website
- southwest.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 57m
- When
- Tuesday and Wednesday
- Estimated price
- $180–1,100
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 4h 5m
- When
- Tuesday and Wednesday
- Estimated price
- $100–600
- Website
- united.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $180–1,100
Flights from Boston Logan Airport to Rochester via Newark
- Ave. Duration
- 3h 51m
- When
- Wednesday and Sunday
- Estimated price
- $85–550
Flights from Boston Logan Airport to Rochester via Washington Dulles
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $110–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 39m
- Frequency
- Once daily
- Estimated price
- $110–250
- Website
- https://www.amtrak.com/home.html
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Bourne to Boston South Station
- Ave. Duration
- 1h 10m
- Frequency
- Every 4 hours
- Estimated price
- $8–35
- Website
- https://peterpanbus.com
- Adult
- $8–35
Bus from Bourne to Boston Airport
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $8–35
- Website
- https://peterpanbus.com
- Adult
- $8–35
Bus from Bourne to Providence Bus Terminal
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $8–35
- Website
- https://peterpanbus.com
- Adult
- $8–35
Bus from Peter Pan Bus Terminal to Port Authority Bus Terminal
- Ave. Duration
- 4h
- Frequency
- Every 4 hours
- Estimated price
- $25–55
- Website
- https://peterpanbus.com
- Adult
- $25–55
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $12–22
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- 5 times a week
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $18–35
- Schedules at
- flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $8–15
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- 5 times a day
- Estimated price
- $28–95
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–90
- Flexible
- $55–95
Bus from New York to Buffalo
- Ave. Duration
- 8h
- Frequency
- Every 4 hours
- Estimated price
- $60–280
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $60–260
- Flexible
- $110–280
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- p-b.com
Bus from Park & Ride, Exit 1A/B - Jct. US 6 to Boston South Buses
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- $22–29
- Website
- https://www.p-b.com
- One Way - Adult
- $22–29
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