There are 9 ways to get from Maryland to South Carolina by plane, subway, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Reagan Washington to Columbia  •  3 h 25 min

  1. Fly from Reagan Washington (DCA) to Columbia (CAE) DCA - CAE

$129 - $637

Cheapest option

Bus  •  10 h 50 min

  1. Take the bus from Baltimore Downtown, Md to Richmond, Va 3005 / ...
  2. Take the bus from Richmond, Va to Florence, Sc 1019

$51 - $135

7 alternative options

Fly Reagan Washington to Greenville/Spartanburg  •  3 h 34 min

  1. Fly from Reagan Washington (DCA) to Greenville/Spartanburg (GSP) DCA - GSP

$155 - $352

Fly Baltimore to Charlotte  •  3 h 21 min

  1. Fly from Baltimore (BWI) to Charlotte (CLT) BWI - CLT

$178 - $356

Fly Baltimore to Charleston  •  4 h 2 min

  1. Fly from Baltimore (BWI) to Charleston (CHS) BWI - CHS

$145 - $609

Subway to Reagan Washington, fly to Charleston  •  4 h 23 min

  1. Take the subway from SILVER SPRING station to GALLERY PLACE CHINATOWN station
  2. Fly from Reagan Washington (DCA) to Charleston (CHS) DCA - CHS

$87 - $350

Line 100 bus, subway, subway to Washington Dulles, fly to Columbia  •  4 h 37 min

  1. Take the line 100 bus from Germantown Transit Center & Bay B to Shady Grove Station & Bay C - East
  2. Take the subway from SHADY GROVE station to FARRAGUT NORTH station
  3. Take the subway from FARRAGUT WEST station to WIEHLE-RESTON EAST station
  4. Fly from Washington Dulles (IAD) to Columbia (CAE) IAD - CAE

$137 - $490

Train  •  8 h 50 min

  1. Take the train from Baltimore Penn Station to Florence Amtrak Palmetto / ...

$70 - $190

Drive  •  7 h 24 min

  1. Drive from Baltimore to Florence 445.5 miles

$40 - $65

Questions & Answers

The cheapest way to get from Maryland to South Carolina is to drive which costs $40 - $65 and takes 7 h 24 min.

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The quickest way to get from Maryland to South Carolina is to fly which costs $170 - $360 and takes 3 h 21 min.

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No, there is no direct bus from Maryland to South Carolina. However, there are services departing from GREENE ST & LOMBARD ST ns sb and arriving at Florence, Sc via Baltimore Downtown, Md and Richmond, Va. The journey, including transfers, takes approximately 10 h 50 min.

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Yes, there is a direct train departing from Baltimore Penn Station station and arriving at Florence Amtrak. Services depart twice daily, and operate every day. The journey takes approximately 8 h 50 min.

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The distance between Maryland and South Carolina is 450 miles. The road distance is 445.5 miles.

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The best way to get from Maryland to South Carolina without a car is to train which takes 8 h 50 min and costs $70 - $190.

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It takes approximately 3 h 25 min to get from Maryland to South Carolina, including transfers.

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Maryland to South Carolina bus services, operated by Greyhound USA, depart from Baltimore Downtown, Md station.

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Maryland to South Carolina train services, operated by Amtrak, arrive at Baltimore Penn Station.

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The best way to get from Maryland to South Carolina is to fly which takes 3 h 25 min and costs $120 - $650. Alternatively, you can train, which costs $70 - $190 and takes 8 h 50 min, you could also bus, which costs $50 - $140 and takes 10 h 50 min.

Mode details

Map of how to get from Maryland to South Carolina.
Launch map view
  • Distance: 449.5 miles
  • Duration: 3 h 25 min

What companies run services between Maryland, USA and South Carolina, USA?

American Airlines and Delta fly from Silver Spring to Columbia every 2 hours. Alternatively, Amtrak operates a train from Baltimore to Florence twice daily. Tickets cost $70 - $190 and the journey takes 8 h 50 min.

Airlines
American Airlines
Website
aa.com
Flights from Reagan Washington to Columbia
Ave. Duration
1 h 43 min
When
Every day
Estimated price
$160 - $1,000
Flights from Reagan Washington to Columbia via Charlotte
Ave. Duration
3 h 28 min
When
Every day
Estimated price
$160 - $1,000
Flights from Reagan Washington to Greenville/Spartanburg
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$180 - $600
Flights from Reagan Washington to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 27 min
When
Every day
Estimated price
$180 - $600
Flights from Reagan Washington to Greenville/Spartanburg via Philadelphia
Ave. Duration
4 h 4 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $600
Flights from Baltimore to Charlotte
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$180 - $490
Flights from Baltimore to Charleston via Charlotte
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$190 - $1,100
Flights from Reagan Washington to Charleston
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$110 - $800
Flights from Reagan Washington to Charleston via Charlotte
Ave. Duration
3 h 34 min
When
Every day
Estimated price
$110 - $800
Flights from Washington Dulles to Columbia via Charlotte
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$170 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Baltimore to Charlotte
Ave. Duration
1 h 28 min
When
Every day
Estimated price
$210 - $550
Flights from Baltimore to Charleston
Ave. Duration
1 h 36 min
When
Every day
Estimated price
$190 - $1,100
Delta
Website
delta.com
Flights from Reagan Washington to Columbia via Atlanta
Ave. Duration
3 h 53 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $1,200
Flights from Reagan Washington to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$220 - $800
JetBlue Airways
Website
jetblue.com
Flights from Reagan Washington to Charleston
Ave. Duration
1 h 41 min
When
Every day
Estimated price
$95 - $700
United Airlines
Website
united.com
Flights from Washington Dulles to Columbia
Ave. Duration
1 h 31 min
When
Every day
Estimated price
$160 - $900
Train operators
Metro Washington DC
Phone
202-637-7000
Website
wmata.com
Subway from SILVER SPRING station to GALLERY PLACE CHINATOWN station
Ave. Duration
20 min
Frequency
Every 10 minutes
Estimated price
$2 - $4
Schedules at
wmata.com
Subway from SHADY GROVE station to FARRAGUT NORTH station
Ave. Duration
36 min
Frequency
Every 10 minutes
Estimated price
$3 - $5
Schedules at
wmata.com
Subway from FARRAGUT WEST station to WIEHLE-RESTON EAST station
Ave. Duration
37 min
Frequency
Every 15 minutes
Estimated price
$3 - $6
Schedules at
wmata.com
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Baltimore Penn Station to Florence Amtrak
Ave. Duration
8 h 50 min
Frequency
Twice daily
Estimated price
$70 - $190
Website
amtrak.com
Coach Seat
$70 - $110
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$300 - $420
Bus operators
Montgomery County MD Ride On
Website
montgomerycountymd.gov
Bus from Germantown Transit Center & Bay B to Shady Grove Station & Bay C - East
Ave. Duration
14 min
Frequency
Every 20 minutes
Estimated price
$2 - $5
Schedules at
montgomerycountymd.gov
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Baltimore Downtown, Md to Richmond, Va
Ave. Duration
3 h 20 min
Frequency
Hourly
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $45
Bus from Richmond, Va to Florence, Sc
Ave. Duration
6 h 45 min
Frequency
Every 30 minutes
Estimated price
$30 - $85
Website
greyhound.com
Economy
$30 - $55
Flexible
$60 - $85

Want to know more about travelling around United States

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More Questions & Answers

The quickest flight from Reagan Washington Airport to Columbia Airport is the direct flight which takes 1 h 34 min.

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Maryland to South Carolina bus services, operated by Greyhound USA, arrive at Florence, Sc station.

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Maryland to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak station.

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Yes, the driving distance between Maryland to South Carolina is 446 miles. It takes approximately 7 h 24 min to drive from Maryland to South Carolina.

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Delta and American Airlines offer flights from Reagan Washington Airport to Columbia Airport.

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Book your Maryland to South Carolina train tickets online with Rome2rio.

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There are 16+ hotels available in South Carolina. Prices start at $52 USD per night.

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