There are 9 ways to get from Maryland Heights to South Carolina by plane, bus, train, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Charlotte  •  3 h 38 min

  1. Fly from St. Louis (STL) to Charlotte (CLT) STL - CLT

$217 - $462

Cheapest option

Bus  •  22 h 41 min

  1. Take the bus from St Louis, Mo to Atlanta, Ga 4703
  2. Take the bus from Atlanta, GA to Florence, SC Atlanta

$97 - $207

7 alternative options

Fly to Greenville/Spartanburg  •  4 h 43 min

  1. Fly from St. Louis (STL) to Greenville/Spartanburg (GSP) STL - GSP

$192 - $457

Fly to Columbia  •  5 h 3 min

  1. Fly from St. Louis (STL) to Columbia (CAE) STL - CAE

$236 - $1,132

Fly to Charleston  •  4 h 25 min

  1. Fly from St. Louis (STL) to Charleston (CHS) STL - CHS

$204 - $605

Fly to Florence  •  5 h

  1. Fly from St. Louis (STL) to Florence (FLO) STL - FLO

$270 - $1,313

Bus, train  •  25 h 29 min

  1. Take the bus from St Louis, Mo to Atlanta, Ga
  2. Take the bus from Atlanta, Ga to Savannah, Ga
  3. Take the train from Savannah Amtrak to Florence Amtrak

$136 - $331

Night bus, bus  •  21 h 35 min

  1. Take the night bus from St Louis, Mo to Atlanta, Ga 4711
  2. Take the bus from Atlanta, Ga to Florence, SC Atlanta

$99 - $209

Drive  •  14 h 12 min

  1. Drive from Maryland Heights to Florence 844 miles

$80 - $120

Questions & Answers

No, there is no direct bus from Maryland Heights to South Carolina. However, there are services departing from Dorsett @ Schuetz Eb and arriving at Florence, SC via Rock Road Transit Center, St Louis, Mo, Peachtree St @ Alabama St and Atlanta, GA. The journey, including transfers, takes approximately 22 h 41 min.

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The distance between Maryland Heights and South Carolina is 660 miles. The road distance is 844 miles.

Get driving directions

The best way to get from Maryland Heights to South Carolina without a car is to bus which takes 22 h 41 min and costs .

More details

It takes approximately 3 h 38 min to get from Maryland Heights to South Carolina, including transfers.

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Maryland Heights to South Carolina bus services, operated by Greyhound USA, depart from St Louis, Mo station.

More details

The best way to get from Maryland Heights to South Carolina is to fly which takes 3 h 38 min and costs . Alternatively, you can bus, which costs and takes 22 h 41 min.

Mode details

The quickest flight from St. Louis Airport to Charlotte Airport is the direct flight which takes 1 h 49 min.

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Maryland Heights to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

More details

South Carolina is 1 h ahead of Maryland Heights. It is currently 12:22 PM in Maryland Heights and 1:22 PM in South Carolina.

Yes, the driving distance between Maryland Heights to South Carolina is 844 miles. It takes approximately 14 h 12 min to drive from Maryland Heights to South Carolina.

Get driving directions

Map of how to get from Maryland Heights to South Carolina.
Launch map view
  • Distance: 659.8 miles
  • Duration: 3 h 38 min

What companies run services between Maryland Heights, MO, USA and South Carolina, USA?

American Airlines, Southwest Airlines and two other airlines fly from Maryland Heights to Rock Hill hourly. Alternatively, you can take a bus from Maryland Heights to Florence via Rock Road Transit Center, Cass @ 20Th Street Eb, St Louis, Mo, Atlanta, Ga, Peachtree St @ Alabama St, Peachtree St Sw @ Brotherton Transportation Mall, and Atlanta, GA in around 22 h 41 min.

Airlines
American Airlines
Website
aa.com
Flights from St. Louis to Charlotte
Ave. Duration
1 h 53 min
When
Every day
Estimated price
$180 - $550
Flights from St. Louis to Greenville/Spartanburg via Charlotte
Ave. Duration
4 h 7 min
When
Every day
Estimated price
$290 - $450
Flights from St. Louis to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
4 h 15 min
When
Monday to Friday
Estimated price
$290 - $450
Flights from St. Louis to Greenville/Spartanburg via Philadelphia
Ave. Duration
4 h 49 min
When
Every day
Estimated price
$290 - $450
Flights from St. Louis to Greenville/Spartanburg via Reagan Washington
Ave. Duration
5 h 2 min
When
Sunday
Estimated price
$290 - $450
Flights from St. Louis to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
5 h 12 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $450
Flights from St. Louis to Columbia via Charlotte
Ave. Duration
4 h 1 min
When
Every day
Estimated price
$230 - $1,100
Flights from St. Louis to Columbia via Reagan Washington
Ave. Duration
5 h 59 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,200
Flights from St. Louis to Columbia via Dallas/Ft.Worth
Ave. Duration
6 h 8 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,300
Flights from St. Louis to Columbia via Philadelphia
Ave. Duration
6 h 18 min
When
Every day
Estimated price
$290 - $1,300
Flights from St. Louis to Charleston via Charlotte
Ave. Duration
4 h 3 min
When
Every day
Estimated price
$340 - $1,200
Flights from St. Louis to Florence via Charlotte
Ave. Duration
4 h 20 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$260 - $1,300
Flights from St. Louis to Florence via Chicago O'Hare, Charlotte
Ave. Duration
7 h 1 min
When
Every day
Estimated price
$290 - $1,300
Flights from St. Louis to Florence via Reagan Washington, Charlotte
Ave. Duration
7 h 29 min
When
Every day
Estimated price
$310 - $1,400
Flights from St. Louis to Florence via Philadelphia, Charlotte
Ave. Duration
8 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$330 - $1,400
Delta
Website
delta.com
Flights from St. Louis to Charlotte via Atlanta
Ave. Duration
3 h 46 min
When
Every day
Estimated price
$180 - $550
Flights from St. Louis to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$300 - $460
Flights from St. Louis to Greenville/Spartanburg via Detroit
Ave. Duration
4 h 58 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $460
Flights from St. Louis to Columbia via Atlanta
Ave. Duration
4 h 29 min
When
Every day
Estimated price
$210 - $1,100
Flights from St. Louis to Columbia via New York La Guardia
Ave. Duration
6 h 59 min
When
Monday, Thursday, Friday and Sunday
Estimated price
$290 - $1,300
Flights from St. Louis to Charleston via Atlanta
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$340 - $1,200
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Charlotte via Nashville
Ave. Duration
3 h 38 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $550
Flights from St. Louis to Charlotte via Chicago Midway
Ave. Duration
4 h 10 min
When
Sunday
Estimated price
$180 - $550
Flights from St. Louis to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 26 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $900
Flights from St. Louis to Charleston
Ave. Duration
2 h 5 min
When
Sunday
Estimated price
$400 - $1,600
Flights from St. Louis to Charleston via Chicago Midway
Ave. Duration
4 h 31 min
When
Every day
Estimated price
$400 - $1,600
United Airlines
Website
united.com
Flights from St. Louis to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
4 h 27 min
When
Every day
Estimated price
$320 - $490
Flights from St. Louis to Greenville/Spartanburg via Washington Dulles
Ave. Duration
4 h 52 min
When
Every day
Estimated price
$320 - $490
Flights from St. Louis to Columbia via Washington Dulles
Ave. Duration
4 h 37 min
When
Every day
Estimated price
$280 - $1,300
Flights from St. Louis to Columbia via Chicago O'Hare
Ave. Duration
5 h 54 min
When
Every day
Estimated price
$270 - $1,300
Flights from St. Louis to Charleston via Washington Dulles
Ave. Duration
4 h 32 min
When
Every day
Estimated price
$340 - $1,200
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Savannah Amtrak to Florence Amtrak
Ave. Duration
3 h 14 min
Frequency
Twice daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Atlanta, Ga
Ave. Duration
13 h 40 min
Frequency
Every 4 hours
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $90
Flexible
$100 - $140
Bus from Atlanta, Ga to Savannah, Ga
Ave. Duration
4 h 35 min
Frequency
Every 30 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Atlanta, GA to Florence, SC
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$35 - $60
Schedules at
southeasternstages.com
Bus from Atlanta, Ga to Florence, SC
Ave. Duration
6 h 55 min
Frequency
3 times a day
Estimated price
$40 - $65
Schedules at
southeasternstages.com

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More Questions & Answers

Delta, American Airlines and Southwest Airlines offer flights from St. Louis Airport to Charlotte Airport.

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There are 17+ hotels available in South Carolina. Prices start at $51 USD per night.

More details

The best way to get from Maryland Heights to St. Louis Airport is to line 49 bus which takes 10 min and costs .

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