There are 7 ways to get from Manzanillo to San Diego by plane, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to San Diego International Airport
best- Fly from Playa De Oro International Airport (ZLO) to San Diego International Airport (SAN)ZLO - SAN
6h 11m$159–646Bus via Santa Ana
- Take the bus from Manzanillo to Santa Ana
- Take the bus from Santa Ana to Mexicali
- Take the bus from Mexicali to Tijuana
28h 46m$183–345Drive 1,522.6 mi
- Drive from Manzanillo to San Diego1,522.6 mi
29h 30m$278–402Fly to Los Angeles International Airport, bus
- Fly from Playa De Oro International Airport (ZLO) to Los Angeles International Airport (LAX)ZLO - LAX
- Take the bus from LAX Terminal 3 Shared Rides Stop to San Diego
7h 47m$174–526Bus, drive, train
- Take the bus from Manzanillo to Santa Ana
- Drive from Santa Ana to 219 N Arroyo Blvd - Nogales
- Take the bus from 219 N Arroyo Blvd - Nogales to 4207 S 6th Ave - Tucson
- Take the train from Tucson Amtrak Station to Los Angeles
- Take the train from Los Angeles to San Diego
34h 20m$265–432Bus
- Take the bus from Manzanillo to Tijuana
- Take the bus from Otay Mesa Transit Center to Broadway & 4th Av225
40h 24m$183–277Bus #2
- Take the bus from Manzanillo to Nueva Central Camionera de Guadalajara Mod 1
- Take the bus from Nueva Central Camionera de Guadalajara Mod 6 to Tijuana
46h 49m$196–425
Playa De Oro International Airport (ZLO) to San Diego International Airport (SAN) flights
Questions & Answers
The cheapest way to get from Manzanillo to San Diego is to bus which costs $180 - $280 and takes 40h 24m.
The fastest way to get from Manzanillo to San Diego is to fly which takes 6h 11m and costs $150 - $650.
No, there is no direct bus from Manzanillo to San Diego. However, there are services departing from Parada en Av. Azul Marino and arriving at San Diego via Manzanillo, Nueva Central Camionera de Guadalajara Mod 6 and Tijuana - Plaza El Mexicano. The journey, including transfers, takes approximately 46h 49m.
The distance between Manzanillo and San Diego is 1248 miles. The road distance is 1531.5 miles.
The best way to get from Manzanillo to San Diego without a car is to bus via Santa Ana which takes 28h 46m and costs $180 - $350.
It takes approximately 6h 11m to get from Manzanillo to San Diego, including transfers.
Manzanillo to San Diego bus services, operated by Primera Plus, depart from Manzanillo station.
The best way to get from Manzanillo to San Diego is to fly which takes 6h 11m and costs $150 - $650. Alternatively, you can bus via Santa Ana, which costs $180 - $350 and takes 28h 46m.
Manzanillo to San Diego bus services, operated by Primera Plus, arrive at Nueva Central Camionera de Guadalajara Mod 1 station.
San Diego is 2h behind Manzanillo. It is currently 6:43 AM in Manzanillo and 4:43 AM in San Diego.
What companies run services between Manzanillo, Mexico and San Diego, CA, USA?
American Airlines, United Airlines, and two other airlines fly from Playa De Oro International Airport (ZLO) to San Diego International Airport (SAN) 6 times a week. Alternatively, you can take a bus from Parada en Av. Elias Zamora Verduzco to Fifth Avenue Station via Parada en Obras Maritimas 42, Manzanillo, Santa Ana, Mexicali, Tijuana, and San Ysidro Station in around 28h 46m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Playa De Oro International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 5h 42m
- When
- Wednesday and Saturday
- Estimated price
- $120–600
Flights from Playa De Oro International Airport to San Diego International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 26m
- When
- Saturday
- Estimated price
- $180–800
Flights from Playa De Oro International Airport to Los Angeles International Airport
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $80–370
Flights from Playa De Oro International Airport to Los Angeles International Airport via Phoenix
- Ave. Duration
- 5h 36m
- When
- Wednesday and Saturday
- Estimated price
- $85–390
- Website
- delta.com
Flights from Playa De Oro International Airport to San Diego International Airport via Los Angeles International Airport
- Ave. Duration
- 8h 3m
- When
- Wednesday and Saturday
- Estimated price
- $130–600
Flights from Playa De Oro International Airport to Los Angeles International Airport via Mexico City
- Ave. Duration
- 6h 49m
- When
- Every day
- Estimated price
- $100–450
- Website
- alaskaair.com
Flights from Playa De Oro International Airport to Los Angeles International Airport
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $80–370
- Website
- aeromexico.com
Flights from Playa De Oro International Airport to Los Angeles International Airport via Mexico City
- Ave. Duration
- 6h 49m
- When
- Every day
- Estimated price
- $100–450
- Website
- united.com
Flights from Playa De Oro International Airport to San Diego International Airport via Houston
- Ave. Duration
- 7h 59m
- When
- Saturday
- Estimated price
- $180–800
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Tucson Amtrak Station to Los Angeles
- Ave. Duration
- 9h 20m
- Frequency
- 6 times a week
- Estimated price
- $50–120
- Website
- https://www.amtrak.com/home.html
Train from Los Angeles to San Diego
- Ave. Duration
- 2h 54m
- Frequency
- Every 2 hours
- Estimated price
- $33–39
- Website
- https://www.amtrak.com/home.html
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- autobuseselite.com.mx
Bus from Manzanillo to Santa Ana
- Ave. Duration
- 14h 49m
- Frequency
- Once daily
- Estimated price
- $130–200
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Santa Ana to Mexicali
- Ave. Duration
- 7h 52m
- Frequency
- 3 times a day
- Estimated price
- $45–70
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Manzanillo to Tijuana
- Ave. Duration
- 37h 42m
- Frequency
- Once daily
- Estimated price
- $180–270
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 644 410 2444
- atencionaclientes@tufesa.com.mx
- Website
- tufesa.com.mx
Bus from Santa Ana to Mexicali
- Ave. Duration
- 7h 20m
- Frequency
- Every 4 hours
- Estimated price
- $35–68
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $35–50
- Titanium
- $40–50
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- chihuahuenses.com.mx
Bus from Santa Ana to Mexicali
- Ave. Duration
- 7h 50m
- Frequency
- 4 times a day
- Estimated price
- $50–95
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 664 299 0487
- servicios@acnautobuses.com
- Website
- acnautobuses.com
Bus from Santa Ana to Mexicali
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $55–80
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
- Phone
- +52 664 104 7400
- servicioalcliente@geb.mx
- Website
- abc.com.mx
Bus from Mexicali to Tijuana
- Ave. Duration
- 2h 5m
- Frequency
- Every 3 hours
- Estimated price
- $16–35
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
- Phone
- (858) 430-8440
- contact@gorelaxsan.com
- Website
- gorelaxsan.com
Bus from LAX Terminal 3 Shared Rides Stop to San Diego
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Website
- https://www.gorelaxsan.com/
- Phone
- (323)-776-5467
- hello@laxlinq.com
- Website
- laxlinq.com
Bus from LAX Terminal 3 Shared Rides Stop to San Diego
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- https://laxlinq.com/
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from 219 N Arroyo Blvd - Nogales to 4207 S 6th Ave - Tucson
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $40–55
- Schedules at
- omnibusexpress.com
- Phone
- +1 619-233-3004
- Website
- sdmts.com
Bus from Otay Mesa Transit Center to Broadway & 4th Av
- Ave. Duration
- 54 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–5
- Website
- https://www.sdmts.com
- Schedules at
- https://www.sdmts.com/getting-around/departures-and-schedules
- One Way - Adult/Youth
- $2–5
- Phone
- +52 477 710 0060
- Website
- primeraplus.com.mx
Bus from Manzanillo to Nueva Central Camionera de Guadalajara Mod 1
- Ave. Duration
- 4h 30m
- Frequency
- Hourly
- Estimated price
- $40–55
- Schedules at
- primeraplus.com.mx
- Book at
- primeraplus.com.mx
- Phone
- +52 55 5141 4300
- contacto@odm.com.mx
- Website
- odm.com.mx
Bus from Nueva Central Camionera de Guadalajara Mod 6 to Tijuana
- Ave. Duration
- 35h 30m
- Frequency
- Every 4 hours
- Estimated price
- $150–330
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
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More Questions & Answers
Yes, the driving distance between Manzanillo to San Diego is 1532 miles. It takes approximately 29h 30m to drive from Manzanillo to San Diego.
There are 2138+ hotels available in San Diego.





































