There are 8 ways to get from Mannheim to Siena by train, plane, train (Trenitalia), bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Frankfurt, fly to Florence Peretola Airport, train
best- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 53m€126–310Bus via Milan
cheapest- Take the bus from Mannheim Central Bus Station to Milanbus MarinoBus 254 / ...
- Take the bus from Milan to Siena Central Train Stationbus Itabus
18h 20m€45–99Train
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 20 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
13h 7m€101–383Bus
- Take the bus from Mannheim central bus station to Florence Villa Constanza Bus Stationbus N77
- Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
16h 57m€54–93Train, night train, bus
- Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain 22 / ...
- Take the night train from Stuttgart Hbf to Venezia Mestrenighttrain Nj
- Take the train from Venezia Mestre to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
17h 58mTrain to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
7h 29m€144–352Train, train to Zurich Airport, fly to Florence Peretola Airport
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Sienatrain
9h 53m€144–424Drive 952.5 km
- Drive from Mannheim to Sienacar 952.5 km
9h 18m€147–212
Mannheim to Siena by train
Questions & Answers
The cheapest way to get from Mannheim to Siena is to bus via Milan which costs €45 - €100 and takes 18h 20m.
The fastest way to get from Mannheim to Siena is to train and fly which takes 6h 53m and costs €120 - €310.
No, there is no direct bus from Mannheim station to Siena. However, there are services departing from Mannheim central bus station and arriving at Siena via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 16h 57m.
No, there is no direct train from Mannheim to Siena. However, there are services departing from Mannheim, Hauptbahnhof and arriving at Siena via Basel SBB, Lugano, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 13h 7m.
The distance between Mannheim and Siena is 893 km. The road distance is 952.5 km.
The best way to get from Mannheim to Siena without a car is to train which takes 13h 7m and costs €100 - €390.
It takes approximately 6h 53m to get from Mannheim to Siena, including transfers.
Mannheim to Siena bus services, operated by FlixBus, depart from Mannheim central bus station.
Mannheim to Siena train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
The best way to get from Mannheim to Siena is to train which takes 13h 7m and costs €100 - €390. Alternatively, you can bus, which costs €50 - €95 and takes 16h 57m.
What companies run services between Mannheim, Germany and Siena, Italy?
You can take a train from Mannheim, Hauptbahnhof to Siena via Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h 7m. Alternatively, you can take a bus from Mannheim central bus station to Siena via Florence Villa Constanza Bus Station in around 16h 57m.
- Website
- lufthansa.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €90–320
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- €110–320
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €90–300
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- €100–310
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €110–350
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €110–320
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €95–300
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 10m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €110–350
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- €120–280
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €75–210
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–28
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 21m
- Frequency
- Hourly
- Estimated price
- €27–65
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- €18–40
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €12–40
- Website
- https://www.ns.nl/en
- 2nd Class
- €12–19
- 1st Class
- €23–40
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €40–140
- Website
- https://www.ns.nl/en
- 2nd Class
- €40–60
- 1st Class
- €80–140
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- 3 times a day
- Estimated price
- €18–60
- Website
- https://www.ns.nl/en
- 2nd Class
- €18–27
- 1st Class
- €30–60
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 59m
- Frequency
- 6 times a week
- Estimated price
- €92–93
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €55–110
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €23–45
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €21–40
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- sbb-deutschland.de
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €30–85
- Schedules at
- trenitalia.com
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €30–60
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €20–65
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 40 min
- Frequency
- 4 times a week
- Estimated price
- €25–60
- Website
- https://www.sncf-connect.com/en-en
- 2nd Class
- €25–35
- 1st Class
- €45–60
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Stuttgart Hbf to Venezia Mestre
- Ave. Duration
- 11h 54m
- Frequency
- Once daily
- Estimated price
- €65–270
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €260–270
- Couchette Carriage
- €150–180
- Seating Carriage
- €65–80
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once a week
- Estimated price
- €26–60
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Mannheim central bus station to Florence Villa Constanza Bus Station
- Ave. Duration
- 15h 25m
- Frequency
- Once daily
- Estimated price
- €45–75
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–14
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 55 min
- Frequency
- 5 times a day
- Estimated price
- €6–18
- Website
- https://www.itabus.it/en/home
Bus from Milan to Siena Central Train Station
- Ave. Duration
- 5h 15m
- Frequency
- Twice daily
- Estimated price
- €9–35
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–14
- Website
- https://marinobus.it/en/
Bus from Mannheim Central Bus Station to Milan
- Ave. Duration
- 12h 5m
- Frequency
- Twice a week
- Estimated price
- €35–65
- Website
- https://marinobus.it/en/
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
Want to know more about travelling around Italy
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More Questions & Answers
Mannheim to Siena bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Mannheim to Siena train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Mannheim to Siena is 953 km. It takes approximately 9h 18m to drive from Mannheim to Siena.
Book your Mannheim to Siena train tickets online with Omio.
Book your Mannheim to Siena bus tickets online with Omio and FlixBus.
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