There are 9 ways to get from Mannheim to Prague by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus RegioJet  •  6 h 40 min

  1. Take the bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Praha, Wilsonova Rj / ...

$17 - $50

8 alternative options

Train  •  7 h 15 min

  1. Take the train from Mannheim Hbf (Busbahnhof) to Praha hl.n. (Autobusová St. Wilsonova)

$90 - $140

Train via Nürnberg ZOB  •  7 h 45 min

  1. Take the train from Mannheim Hbf to Frankfurt(Main)Hbf Ice / ...
  2. Take the train from Frankfurt(Main)Hbf to Nürnberg Hbf Ice / ...
  3. Take the train from Nürnberg ZOB to Praha hl.n. (Autobusová St. Wilsonova)

$106 - $162

Bus Eurolines DE  •  8 h 53 min

  1. Take the bus from Heidelberg Hbf to Prague

$56 - $82

Drive  •  4 h 34 min

  1. Drive from Mannheim to Prague 321.4 miles

$65 - $100

Train to Frankfurt, fly to Prague  •  4 h 10 min

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Prague (PRG) FRA - PRG

$79 - $254

Train to Frankfurt, fly to Dresden, bus  •  5 h 45 min

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Dresden (DRS) FRA - DRS
  3. Take the bus from Drážďany, Letiště to Praha, ÚAN Florenc

$92 - $289

Train to Munich, fly to Prague  •  6 h 28 min

  1. Take the train from Mannheim Hbf to München Hbf
  2. Fly from Munich (MUC) to Prague (PRG) MUC - PRG

$166 - $416

Train to Stuttgart, fly to Dresden, bus  •  6 h 49 min

  1. Take the train from Mannheim Hbf to Stuttgart Hbf
  2. Fly from Stuttgart (STR) to Dresden (DRS) STR - DRS
  3. Take the bus from Drážďany, Letiště to Praha, ÚAN Florenc

$85 - $261

Questions & Answers

The cheapest way to get from Mannheim to Prague is to bus which costs 14€ - 45€ and takes 6 h 40 min.

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The quickest way to get from Mannheim to Prague is to train and fly which costs 65€ - 230€ and takes 4 h 10 min.

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The distance between Mannheim and Prague is 432 km. The road distance is 514.2 km.

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The bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Praha, Wilsonova takes 6 h 40 min including transfers and departs twice daily.

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Yes, there is a direct bus departing from Mannheim, ZOB Heinrich von Stephan Str. 6 and arriving at Praha, Wilsonova. Services depart twice daily, and operate every day. The journey takes approximately 6 h 40 min.

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Yes, there is a direct train departing from Mannheim Hbf (Busbahnhof) and arriving at Praha hl.n. (Autobusová St. Wilsonova). Services depart three times a day. The journey takes approximately 7 h 15 min.

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The quickest flight from Frankfurt Airport to Prague Airport is the direct flight which takes 1 h.

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Mannheim to Prague train services, operated by Deutsche Bahn, arrive at Praha station.

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Map of how to get from Mannheim to Prague.
Launch map view
  • Distance: 270.3 miles
  • Duration: 6 h 40 min

What companies run services between Mannheim, Germany and Prague, Czech Republic?

RegioJet operates a bus from Mannheim to Prague once daily. Tickets cost $17 - $22 and the journey takes 6 h 40 min. FlixBus also services this route once daily. Alternatively, Deutsche Bahn operates a train from Mannheim to Prague 3 times a day. Tickets cost $90 - $140 and the journey takes 7 h 15 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Prague
Ave. Duration
1 h
When
Every day
Estimated price
$100 - $480
Flights from Frankfurt to Prague via Munich
Ave. Duration
2 h 52 min
When
Every day
Estimated price
$100 - $480
Flights from Frankfurt to Dresden
Ave. Duration
55 min
When
Every day
Estimated price
$85 - $290
Flights from Frankfurt to Dresden via Munich
Ave. Duration
2 h 43 min
When
Every day
Estimated price
$85 - $290
Flights from Munich to Prague
Ave. Duration
55 min
When
Every day
Estimated price
$100 - $430
Flights from Stuttgart to Dresden via Munich
Ave. Duration
2 h 58 min
When
Every day
Estimated price
$140 - $470
Flights from Stuttgart to Dresden via Frankfurt
Ave. Duration
2 h 50 min
When
Saturday and Sunday
Estimated price
$140 - $470
Flights from Stuttgart to Dresden via Zurich
Ave. Duration
2 h 50 min
When
Monday to Saturday
Estimated price
$120 - $3,000
Eurowings
Website
eurowings.com
Flights from Stuttgart to Dresden
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$50 - $440
CSA
Website
csa.cz
Flights from Frankfurt to Prague
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$60 - $360
Swiss
Website
swiss.com
Flights from Stuttgart to Dresden via Zurich
Ave. Duration
2 h 50 min
When
Monday to Saturday
Estimated price
$120 - $3,000
Train operators
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Mannheim Hbf (Busbahnhof) to Praha hl.n. (Autobusová St. Wilsonova)
Ave. Duration
7 h 15 min
Frequency
3 times a day
Estimated price
$90 - $140
Website
bahn.de
Train from Mannheim Hbf to Frankfurt(Main)Hbf
Ave. Duration
36 min
Frequency
Hourly
Estimated price
$22 - $35
Website
bahn.de
Train from Frankfurt(Main)Hbf to Nürnberg Hbf
Ave. Duration
2 h 5 min
Frequency
Hourly
Estimated price
$45 - $70
Website
bahn.de
Train from Nürnberg ZOB to Praha hl.n. (Autobusová St. Wilsonova)
Ave. Duration
3 h 35 min
Frequency
5 times a day
Estimated price
$40 - $60
Website
bahn.de
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
30 min
Frequency
Hourly
Estimated price
$21 - $35
Website
bahn.de
Train from Mannheim Hbf to München Hbf
Ave. Duration
2 h 57 min
Frequency
Hourly
Estimated price
$70 - $100
Website
bahn.de
Train from Mannheim Hbf to Stuttgart Hbf
Ave. Duration
38 min
Frequency
Hourly
Estimated price
$28 - $40
Website
bahn.de
TGV
Phone
0033 892 353535
Website
sncf.com
Train from Mannheim Hbf to Frankfurt(Main)Hbf
Ave. Duration
39 min
Frequency
3 times a day
Estimated price
$20 - $25
Website
en.oui.sncf
2nd Class
$20 - $25
1st Class
$36 - $39
Bus operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Praha, Wilsonova
Ave. Duration
6 h 40 min
Frequency
Once daily
Estimated price
$17 - $22
Schedules at
regiojet.sk
Bus from Drážďany, Letiště to Praha, ÚAN Florenc
Ave. Duration
2 h 20 min
Frequency
Every 4 hours
Estimated price
$5 - $8
Schedules at
regiojet.sk
FlixBus
Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Mannheim, Mannheim ZOB to Prague, Prague Anděl
Ave. Duration
7 h 10 min
Frequency
Once daily
Estimated price
$28 - $50
Website
flixbus.co.uk
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Heidelberg Hbf to Prague
Ave. Duration
7 h 15 min
Frequency
3 times a week
Estimated price
$50 - $75
Website
eurolines.de

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