COVID-19 Travel restrictions may apply upon entering Czech Republic. Learn More.

There are 5 ways to get from Mannheim to Prague by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  6h 40m

  1. Take the bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Prague, Wilsonova RegioJet

380 Kč - 550 Kč

4 alternative options

Train  •  9h 10m

  1. Take the train from Mannheim Hbf to Frankfurt(Main)Hbf Ice / ...
  2. Take the train from Frankfurt(Main)Hbf to Dresden-Neustadt Ice
  3. Take the train from Dresden-Neustadt to Praha-Holesovice Ec / ...

3 088 Kč - 5 611 Kč

Drive  •  4h 30m

  1. Drive from Mannheim to Prague 513.4 km

1 400 Kč - 2 100 Kč

Train, fly to Prague  •  4h

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Prague (PRG) FRA - PRG

1 732 Kč - 6 805 Kč

Train, fly to Dresden  •  6h 20m

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Dresden (DRS) FRA - DRS
  3. Take the train from Dresden-Neustadt to Praha-Holesovice

2 609 Kč - 9 946 Kč

Mannheim to Prague by bus

The bus journey time between Mannheim and Prague is around 6h 40m and covers a distance of around 511 km. The fastest bus normally takes 6h 40m. Operated by RegioJet, the Mannheim to Prague bus service departs from Mannheim, ZOB Heinrich von Stephan Str. 6 and arrives in Prague, Wilsonova. Typically three buses run weekly, although weekend and holiday schedules can vary so check in advance.

The schedules shown below are for the next available departures.

Mannheim to Prague bus schedules

Germany → Czech Republic
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International entry into Czech Republic from Germany

  • Entry is restricted for citizens and permanent residents of Germany
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Allowed for: Citizens and permanent residents of Czech Republic, as well as residents from Australia, New Zealand, Singapore, South Korea and Thailand

Restricted for: Foreign nationals, with the above exceptions

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Conditions of entry into Czech Republic from Germany

  • Entry is allowed only for essential reasons
  • Passenger Locator Form (PLF) required
This applies to arrivals from all countries, with no exceptions
  • Negative COVID-19 test issued at most 3 days before arrival and 14 day mandatory self quarantine
  • COVID-19 test 5 days after arrival
  • Negative COVID-19 result is required for quarantine release
This applies to arrivals from Germany
Show more details
  • Entry is allowed only for essential reasons
  • Passenger Locator Form (PLF) required
This applies to arrivals from all countries, with no exceptions
  • Negative COVID-19 test issued at most 3 days before arrival and 14 day mandatory self quarantine
  • COVID-19 test 5 days after arrival
  • Negative COVID-19 result is required for quarantine release
This doesn't apply to arrivals from: Australia, New Zealand, Thailand, South Korea and Singapore

Show less

Rules to follow in Czech Republic

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Considerations leaving from Germany

The official advice is to avoid non-essential international travel to high risk countries

Frequently Asked Questions


No, entry into Czech Republic from Germany is currently restricted.

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Domestic travel is restricted

  • Face masks are mandatory
  • There is a social distancing requirement of 1 metre
  • Nationwide control measures in place

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The national COVID-19 helpline number in Prague is 1221.

Wearing a face mask on public transport in Prague is mandatory.

The social distance requirement in Prague is 1 metre.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 1221.

Yes, entry into Germany from Czech Republic is currently restricted.

Explore options for future travel.

Last updated: 16 May 2021
Exceptions may apply, for full details: European Union.

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The cheapest way to get from Mannheim to Prague is to bus which costs 14€ - 21€ and takes 6h 40m.

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The quickest way to get from Mannheim to Prague is to train and fly which costs 65€ - 270€ and takes 4h.

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Yes, there is a direct bus departing from Mannheim, ZOB Heinrich von Stephan Str. 6 and arriving at Prague, Wilsonova. Services depart five times a week, and operate Tuesday, Wednesday and Sunday. The journey takes approximately 6h 40m.

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No, there is no direct train from Mannheim to Prague. However, there are services departing from Mannheim Hbf and arriving at Praha-Holesovice via Frankfurt(Main)Hbf and Dresden-Neustadt. The journey, including transfers, takes approximately 9h 10m.

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The distance between Mannheim and Prague is 432 km. The road distance is 513.4 km.

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The best way to get from Mannheim to Prague without a car is to bus which takes 6h 40m and costs 14€ - 21€.

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The bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Prague, Wilsonova takes 6h 40m including transfers and departs five times a week.

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Mannheim to Prague bus services, operated by RegioJet, depart from Mannheim, ZOB Heinrich von Stephan Str. 6 station.

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Mannheim to Prague train services, operated by Deutsche Bahn Intercity-Express, depart from Mannheim Hbf station.

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The best way to get from Mannheim to Prague is to bus which takes 6h 40m and costs 14€ - 21€. Alternatively, you can train, which costs 110€ - 220€ and takes 9h 10m.

Mode details

Map of how to get from Mannheim to Prague.
Launch map view
  • Distance: 432.5 km
  • Duration: 6h 40m

What companies run services between Mannheim, Germany and Prague, Czech Republic?

RegioJet operates a bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Prague, Wilsonova 5 times a week. Tickets cost 380 Kč - 550 Kč and the journey takes 6h 40m. Alternatively, you can take a train from Mannheim to Prague via Frankfurt(Main)Hbf and Dresden-Neustadt in around 9h 10m.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Prague
Ave. Duration
1h
When
Every day
Estimated price
2 200 Kč - 8 500 Kč
Flights from Frankfurt to Dresden
Ave. Duration
55 min
When
Every day
Estimated price
1 600 Kč - 6 000 Kč
Train operators
Deutsche Bahn Intercity-Express

German rail company Deutsche Bahn is known for its efficient and comfortable service. It offers many different types of rail transportation, including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare (bookings usually open 6 months in advance for domestic tickets).

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Mannheim Hbf to Frankfurt(Main)Hbf
Ave. Duration
36 min
Frequency
Every 30 minutes
Estimated price
550 Kč - 800 Kč
Website
Deutsche Bahn
Train from Frankfurt(Main)Hbf to Dresden-Neustadt
Ave. Duration
4h 10m
Frequency
Every 4 hours
Estimated price
2 200 Kč - 3 100 Kč
Website
Deutsche Bahn
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
31 min
Frequency
Hourly
Estimated price
550 Kč - 750 Kč
Website
Deutsche Bahn
Deutsche Bahn Regional

Deutsche Bahn’s regional network is made up of IRE (Interregio-Express), RE (Regional-Express), RB (Regionalbahn) and S-Bahn trains. Ticket prices are fixed and there’s no seat reservations – just turn up, buy a ticket and jump on the next train. All regional trains depart regularly and connect to local and long-distance services.

Contact Details
Phone
+49 30 2970
Website
bahn.com
Train from Mannheim Hbf to Frankfurt(Main)Hbf
Ave. Duration
1h 9m
Frequency
Every 30 minutes
Estimated price
330 Kč - 470 Kč
Website
reiseauskunft.bahn.de
TGV inOui

France’s high-speed TGV train network runs at speeds of up to 320km/h connecting major cities across France and into neighbouring countries. All TGV tickets include a seat reservation; seating is 1+2 in 1st class, 2+2 in 2nd class. Popular routes include Paris to Marseille and Paris to Strasbourg. Most TGVs have a cafe area, power points at each seat and WiFi.

Contact Details
Phone
0033 892 353535
Website
en.oui.sncf
Train from Mannheim Hbf to Frankfurt(Main)Hbf
Ave. Duration
40 min
Frequency
4 times a day
Estimated price
600 Kč - 900 Kč
Website
Oui.SNCF
2nd Class
750 Kč - 900 Kč
1st Class
600 Kč - 700 Kč
Deutsche Bahn Intercity

Deutsche Bahn’s high-speed InterCity (IC) trains connect cities within Germany. They’re a popular way to travel as they’re faster than Deutsche Bahn’s regional trains and offer a frequent, fast service. All IC trains have first and second class carriages, power sockets and toilets, and most have a bistro cafe or restaurant. Tickets can be booked up to 180 days in advance of travel.

Contact Details
Phone
+49 30 2970
Website
bahn.com
Train from Mannheim Hbf to Frankfurt(Main)Hbf
Ave. Duration
41 min
Frequency
5 times a week
Estimated price
1 000 Kč - 1 500 Kč
Website
reiseauskunft.bahn.de
Hungarian Railways (MÁV)
Phone
+36 (1) 3 49 49 49
Website
mavcsoport.hu
Train from Mannheim Hbf to Frankfurt(Main)Hbf
Ave. Duration
50 min
Frequency
Twice a week
Estimated price
100 Kč - 120 Kč
Website
mavcsoport.hu
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
32 min
Frequency
Twice a week
Estimated price
90 Kč - 110 Kč
Website
mavcsoport.hu
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs.

Contact Details
Phone
+41 51 220 11 11
Website
sbb.ch
Train from Mannheim Hbf to Frankfurt(Main)Hbf
Ave. Duration
44 min
Frequency
Once daily
Estimated price
700 Kč - 1 300 Kč
Website
Swiss Railways (SBB/CFF/FFS)
Railjet

Railjet trains operate domestically within Austria and also connect to major cities in Germany, Czech Republic, Italy, Switzerland and Hungary. This premium service runs at speeds of up to 230km/h and offers three travel classes (economy, first and business), all with free Wi-Fi and power sockets. Other amenities include a bistro-restaurant car and family zones. Seat reservations can be made up to 90 days prior to the train's departure (compulsory for all cross-border trains but not for domestic routes).

Contact Details
Phone
+43 51717
Website
oebb.at
Train from Mannheim Hbf to Frankfurt(Main)Hbf
Ave. Duration
50 min
Frequency
Twice a week
Estimated price
400 Kč - 600 Kč
Website
Railjet
Train from Dresden-Neustadt to Praha-Holesovice
Ave. Duration
2h 18m
Frequency
Once daily
Estimated price
700 Kč - 1 100 Kč
Website
Railjet
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
32 min
Frequency
Twice a week
Estimated price
380 Kč - 600 Kč
Website
Railjet
Austrian Railways (ÖBB)

Austria's national railway system is not only punctual, reliable and efficient, but offers free wifi to boot. Choose from high-speed intercity Railjet trains, overnight Nightjet trains and regional services such as Cityjet. ÖBB also operates international routes that connect cities in Austria with adjacent European countries including Germany, Hungary, Liechtenstein, Czech Republic, Switzerland and Slovenia. If you're planning to be in Austria for a while, consider the ÖBB Vorteilscard, an annual railcard that offers discounts on routes within Austria and in neighbouring countries.

Contact Details
Phone
05 17 17
Website
oebb.at
Train from Mannheim Hbf to Frankfurt(Main)Hbf
Ave. Duration
55 min
Frequency
Once a week
Estimated price
350 Kč - 470 Kč
Website
Austrian Railways
Book at
Austria Rail Pass
Deutsche Bahn Eurocity

Deutsche Bahn’s EuroCity (EC) trains connect German cities to major cities in neighbouring European countries, and are operated in conjunction with their national train company. All EC trains offer First and Standard class; cars are air-conditioned and food and drinks are available onboard. Tickets can be booked up to 180 days in advance of travel. Seat reservations are not compulsory but are recommended for popular routes.

Contact Details
Phone
+49 30 2970
Website
bahn.com
Train from Dresden-Neustadt to Praha-Holesovice
Ave. Duration
2h 24m
Frequency
Every 4 hours
Estimated price
550 Kč - 800 Kč
Website
reiseauskunft.bahn.de
Bus operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.com
Bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Prague, Wilsonova
Ave. Duration
6h 40m
Frequency
5 times a week
Estimated price
380 Kč - 550 Kč
Website
RegioJet

Want to know more about travelling around Czechia

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More Questions & Answers

The quickest flight from Frankfurt Airport to Prague Airport is the direct flight which takes 1h.

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Mannheim to Prague bus services, operated by RegioJet, arrive at Prague, Wilsonova station.

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Mannheim to Prague train services, operated by Deutsche Bahn Eurocity, arrive at Praha-Holesovice station.

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Yes, the driving distance between Mannheim to Prague is 513 km. It takes approximately 4h 30m to drive from Mannheim to Prague.

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Lufthansa offers flights from Frankfurt Airport to Prague Airport.

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Book your Mannheim to Prague train tickets online with Omio.

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Book your Mannheim to Prague bus tickets online with Omio and Distribusion.

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There are 909+ hotels available in Prague. Prices start at 2 000 Kč per night.

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