There are 7 ways to get from Mannheim to Prague by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  6h 40m

  1. Take the bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Prague, Wilsonova RegioJet / ...

400 Kč - 850 Kč

6 alternative options

Bus via Heidelberg, Hauptbahnhof Bstg B  •  8h 57m

  1. Take the bus from Heidelberg Hbf to Prague

1 336 Kč - 1 968 Kč

Train  •  9h 3m

  1. Take the train from Mannheim Hbf to Dresden Hbf Ice
  2. Take the train from Dresden Hbf to Praha Hlavni Nadrazi Ec / ...

3 318 Kč - 4 897 Kč

Drive  •  4h 43m

  1. Drive from Mannheim to Prague 513.5 km

1 600 Kč - 2 400 Kč

Train to Frankfurt, fly to Prague  •  4h

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Prague (PRG) FRA - PRG

1 387 Kč - 5 247 Kč

Train to Frankfurt, fly to Dresden, bus  •  5h 13m

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Dresden (DRS) FRA - DRS
  3. Take the bus from Dresden, Dresden central station to Prague, Prague ÚAN Florenc

2 055 Kč - 14 421 Kč

Train to Stuttgart, fly to Dresden, bus  •  6h 1m

  1. Take the train from Mannheim Hbf to Stuttgart Hbf
  2. Fly from Stuttgart (STR) to Dresden (DRS) STR - DRS
  3. Take the bus from Dresden, Dresden central station to Prague, Prague ÚAN Florenc

2 068 Kč - 8 654 Kč

Questions & Answers

There is widespread community transmission in Czech Republic.
Last Updated: 3/11/2020 | Source: CDC.

Heavy travel restrictions apply and transportation services are subject to change. Please check before you travel.

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The cheapest way to get from Mannheim to Prague is to bus which costs 14€ - 30€ and takes 6h 40m.

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The quickest way to get from Mannheim to Prague is to train and fly which costs 50€ - 200€ and takes 4h.

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Yes, there is a direct bus departing from Mannheim, ZOB Heinrich von Stephan Str. 6 and arriving at Prague, Wilsonova. Services depart five times a week, and operate Tuesday, Wednesday, Thursday and Sunday. The journey takes approximately 6h 40m.

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No, there is no direct train from Mannheim to Prague. However, there are services departing from Mannheim Hbf and arriving at Praha Hlavni Nadrazi via Dresden Hbf. The journey, including transfers, takes approximately 9h 3m.

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The distance between Mannheim and Prague is 432 km. The road distance is 513.5 km.

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The best way to get from Mannheim to Prague without a car is to bus which takes 6h 40m and costs 14€ - 30€.

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The bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Prague, Wilsonova takes 6h 40m including transfers and departs five times a week.

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Mannheim to Prague bus services, operated by RegioJet, depart from Mannheim, ZOB Heinrich von Stephan Str. 6 station.

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Mannheim to Prague train services, operated by Deutsche Bahn Intercity-Express, depart from Mannheim Hbf station.

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Map of how to get from Mannheim to Prague.
Launch map view
  • Distance: 432.5 km
  • Duration: 6h 40m

What companies run services between Mannheim, Germany and Prague, Czech Republic?

RegioJet operates a bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Prague, Wilsonova 5 times a week. Tickets cost 400 Kč - 550 Kč and the journey takes 6h 40m. FlixBus also services this route 3 times a week. Alternatively, you can take a train from Mannheim to Prague via Dresden Hbf in around 9h 3m.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Prague
Ave. Duration
1h
When
Every day
Estimated price
2 300 Kč - 12 000 Kč
Flights from Frankfurt to Prague via Munich
Ave. Duration
2h 42m
When
Every day
Estimated price
2 300 Kč - 12 000 Kč
Flights from Frankfurt to Dresden
Ave. Duration
55 min
When
Every day
Estimated price
2 700 Kč - 11 000 Kč
Flights from Stuttgart to Dresden via Munich
Ave. Duration
2h 47m
When
Every day
Estimated price
4 500 Kč - 12 000 Kč
Flights from Stuttgart to Dresden via Frankfurt
Ave. Duration
2h 55m
When
Every day
Estimated price
4 500 Kč - 12 000 Kč
Eurowings
Website
eurowings.com
Flights from Stuttgart to Dresden
Ave. Duration
1h 10m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
1 500 Kč - 9 500 Kč
CSA
Website
csa.cz
Flights from Frankfurt to Prague
Ave. Duration
1h 15m
When
Every day
Estimated price
1 000 Kč - 6 000 Kč
Train operators
Deutsche Bahn Intercity-Express

German rail company Deutsche Bahn is known for its efficient and comfortable service. It offers many different types of rail transportation, including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare (bookings usually open 6 months in advance for domestic tickets).

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Mannheim Hbf to Dresden Hbf
Ave. Duration
5h 37m
Frequency
Once a week
Estimated price
2 700 Kč - 3 700 Kč
Website
Deutsche Bahn
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
30 min
Frequency
Hourly
Estimated price
550 Kč - 800 Kč
Website
Deutsche Bahn
Train from Mannheim Hbf to Stuttgart Hbf
Ave. Duration
38 min
Frequency
Hourly
Estimated price
700 Kč - 1 000 Kč
Website
Deutsche Bahn
Deutsche Bahn Eurocity

Deutsche Bahn’s EuroCity (EC) trains connect German cities to major cities in neighbouring European countries, and are operated in conjunction with their national train company. All EC trains offer First and Standard class; cars are air-conditioned and food and drinks are available onboard. Tickets can be booked up to 180 days in advance of travel. Seat reservations are not compulsory but are recommended for popular routes.

Contact Details
Website
bahn.com
Train from Dresden Hbf to Praha Hlavni Nadrazi
Ave. Duration
2h 26m
Frequency
Every 4 hours
Estimated price
600 Kč - 900 Kč
Website
reiseauskunft.bahn.de
Train from Mannheim Hbf to Stuttgart Hbf
Ave. Duration
51 min
Frequency
Twice daily
Estimated price
440 Kč - 650 Kč
Website
reiseauskunft.bahn.de
Railjet

Railjet trains operate domestically within Austria and also connect to major cities in Germany, Czech Republic, Italy, Switzerland and Hungary. This premium service runs at speeds of up to 230km/h and offers three travel classes (economy, first and business), all with free Wi-Fi and power sockets. Other amenities include a bistro-restaurant car and family zones. Seat reservations can be made up to 90 days prior to the train's departure (compulsory for all cross-border trains but not for domestic routes).

Contact Details
Phone
+43 51717
Website
oebb.at
Train from Dresden Hbf to Praha Hlavni Nadrazi
Ave. Duration
2h 21m
Frequency
Once daily
Estimated price
750 Kč - 1 200 Kč
Website
Railjet
Train from Mannheim Hbf to Stuttgart Hbf
Ave. Duration
40 min
Frequency
Twice a week
Estimated price
500 Kč - 800 Kč
Website
Railjet
Austrian Railways (ÖBB)

Austria's national railway system is not only punctual, reliable and efficient, but offers free wifi to boot. Choose from high-speed intercity Railjet trains, overnight Nightjet trains and regional services such as Cityjet. ÖBB also operates international routes that connect cities in Austria with adjacent European countries including Germany, Hungary, Liechtenstein, Czech Republic, Switzerland and Slovenia. If you're planning to be in Austria for a while, consider the ÖBB Vorteilscard, an annual railcard that offers discounts on routes within Austria and in neighbouring countries.

Contact Details
Phone
05 17 17
Website
oebb.at
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
32 min
Frequency
Once a week
Estimated price
340 Kč - 460 Kč
Website
Austrian Railways
Book at
Austria Rail Pass
Flixtrain
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixtrain.com
Train from Mannheim, Mannheim Hbf to Stuttgart, Stuttgart central station
Ave. Duration
1h 9m
Frequency
Hourly
Estimated price
210 Kč - 270 Kč
Website
Flixtrain
Deutsche Bahn Intercity

Deutsche Bahn’s high-speed InterCity (IC) trains connect cities within Germany. They’re a popular way to travel as they’re faster than Deutsche Bahn’s regional trains and offer a frequent, fast service. All IC trains have first and second class carriages, power sockets and toilets, and most have a bistro cafe or restaurant. Tickets can be booked up to 180 days in advance of travel.

Contact Details
Website
bahn.com
Train from Mannheim Hbf to Stuttgart Hbf
Ave. Duration
1h 24m
Frequency
Every 3 hours
Estimated price
1 100 Kč - 1 700 Kč
Website
reiseauskunft.bahn.de
TGV inOui

France’s high-speed TGV train network runs at speeds of up to 320km/h connecting major cities across France and into neighbouring countries. All TGV tickets include a seat reservation; seating is 1+2 in 1st class, 2+2 in 2nd class. Popular routes include Paris to Marseille and Paris to Strasbourg. Most TGVs have a cafe area, power points at each seat and WiFi.

Contact Details
Phone
0033 892 353535
Website
en.oui.sncf
Train from Mannheim Hbf to Stuttgart Hbf
Ave. Duration
44 min
Frequency
Once daily
Estimated price
750 Kč - 1 100 Kč
Website
Oui.SNCF
2nd Class
900 Kč - 1 100 Kč
1st Class
750 Kč - 900 Kč
Verkehrs- und Tarifverbund Stuttgart (VVS)
Phone
0711 19449
Website
vvs.de
Train from Mannheim Hauptbahnhof to Hauptbahnhof
Ave. Duration
2h 7m
Frequency
6 times a week
Estimated price
320 Kč - 420 Kč
Website
Verkehrs- und Tarifverbund Stuttgart (VVS)
Bus operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.com
Bus from Mannheim, ZOB Heinrich von Stephan Str. 6 to Prague, Wilsonova
Ave. Duration
6h 40m
Frequency
5 times a week
Estimated price
400 Kč - 550 Kč
Website
RegioJet
Bus from Dresden, Hbf., Bayrische Str. to Prague, ÚAN Florenc
Ave. Duration
1h 55m
Frequency
Hourly
Estimated price
120 Kč - 160 Kč
Website
RegioJet
FlixBus

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Mannheim, Mannheim ZOB to Prague, Prague Anděl
Ave. Duration
7h 30m
Frequency
3 times a week
Estimated price
650 Kč - 850 Kč
Website
flixbus.co.uk
Bus from Dresden, Dresden central station to Prague, Prague ÚAN Florenc
Ave. Duration
1h 50m
Frequency
Hourly
Estimated price
270 Kč - 330 Kč
Website
flixbus.co.uk
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Heidelberg Hbf to Prague
Ave. Duration
7h 15m
Frequency
3 times a week
Estimated price
1 200 Kč - 1 800 Kč
Website
eurolines.de
Bus from Dresden to Prague
Ave. Duration
2h 3m
Frequency
Twice daily
Estimated price
900 Kč - 1 300 Kč
Website
eurolines.de
Eurolines FR

Eurolines is a network of coach companies that operate throughout Europe plus Morocco. It’s an affordable way to travel around the continent, with tickets starting at €5. All coaches have Wi-Fi, plug sockets and USBs, reclining chairs and toilets, and a standard ticket includes up to two medium suitcases plus carry-on luggage. Within France, Eurolines serves 69 destinations; including Paris, Lyon, Versailles, Nice and Bordeaux.

Contact Details
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Dresden to Prague, Florenc
Ave. Duration
2h
Frequency
Every 4 hours
Estimated price
440 Kč - 650 Kč
Website
Eurolines FR
Racic Eurobus
Phone
+359-887-208-506
Email
racic_bg@yahoo.com
Website
racicbg.com
Bus from Dresden Central Train Station to Prague Florenc Central Bus Station
Ave. Duration
2h
Frequency
5 times a week
Website
Racic Eurobus
Comati PSG
Phone
0040 723 450 475
Email
info@comati-psg.ro
Website
comati-psg.ro
Bus from Dresden Bayrische Strasse to Prague Florenc Central Bus Station
Ave. Duration
2h
Frequency
3 times a week
Estimated price
2 100 Kč - 2 500 Kč
Website
Comati PSG

Want to know more about travelling around Czechia

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More Questions & Answers

The best way to get from Mannheim to Prague is to bus which takes 6h 40m and costs 14€ - 30€. Alternatively, you can train, which costs 120€ - 180€ and takes 9h 3m.

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The quickest flight from Frankfurt Airport to Prague Airport is the direct flight which takes 1h.

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Mannheim to Prague bus services, operated by RegioJet, arrive at Prague, Wilsonova station.

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Mannheim to Prague train services, operated by Deutsche Bahn Eurocity, arrive at Praha Hlavni Nadrazi station.

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Yes, the driving distance between Mannheim to Prague is 513 km. It takes approximately 4h 43m to drive from Mannheim to Prague.

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CSA and Lufthansa offer flights from Frankfurt Airport to Prague Airport.

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Book your Mannheim to Prague train tickets online with Omio and Omio.

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Book your Mannheim to Prague bus tickets online with Omio, Distribusion and FlixBus.

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There are 2092+ hotels available in Prague. Prices start at 2 250 Kč per night.

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