There are 9 ways to get from Mannheim to Grenoble by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train TGV  •  7 h

  1. Take the train from Mannheim Hbf to Lyon Part Dieu Tgv
  2. Take the train from Lyon Part Dieu to Grenoble

$148 - $170

Cheapest option

Train, bus  •  12 h 37 min

  1. Take the train from Mannheim Hbf to Karlsruhe Hbf Ice / ...
  2. Take the bus from Karlsruhe to Grenoble 720

$52 - $93

7 alternative options

Train via Biel/Bienne  •  9 h 23 min

  1. Take the train from Mannheim Hbf to Basel SBB Ice / ...
  2. Take the train from Basel SBB to Biel/Bienne 51
  3. Take the train from Biel/Bienne to Genève 5 / ...
  4. Take the train from Genève to Grenoble

$140 - $252

Drive  •  6 h 7 min

  1. Drive from Mannheim to Grenoble 405.4 miles

$85 - $130

Train to Frankfurt, fly to Lyon, train  •  5 h 48 min

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Lyon (LYS) FRA - LYS
  3. Take the train from Lyon-St Exupery(TGV) to Grenoble

$114 - $317

Train to Strasbourg, fly to Lyon, train  •  6 h 14 min

  1. Take the train from Mannheim Hbf to Offenburg
  2. Fly from Strasbourg (SXB) to Lyon (LYS) SXB - LYS
  3. Take the train from Lyon-St Exupery(TGV) to Grenoble

$131 - $472

Train to Frankfurt, fly to Geneva, train  •  7 h 12 min

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Geneva (GVA) FRA - GVA
  3. Take the train from Genève to Grenoble

$132 - $347

Train to Stuttgart, fly to Lyon, train  •  6 h 37 min

  1. Take the train from Mannheim Hbf to Stuttgart Hbf
  2. Fly from Stuttgart (STR) to Lyon (LYS) STR - LYS
  3. Take the train from Lyon-St Exupery(TGV) to Grenoble

$137 - $357

Train to Frankfurt, fly to Turin, train  •  9 h 15 min

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Turin (TRN) FRA - TRN
  3. Take the train from Torino Porta Susa to Chambery-Challes-E
  4. Take the train from Chambery-Challes-E to Grenoble

$165 - $417

Questions & Answers

The cheapest way to get from Mannheim to Grenoble is to train and bus which costs 45€ - 85€ and takes 12 h 37 min.

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The quickest way to get from Mannheim to Grenoble is to train and fly which costs 95€ - 280€ and takes 5 h 48 min.

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No, there is no direct train from Mannheim to Grenoble. However, there are services departing from Mannheim Hbf and arriving at Grenoble via Lyon Part Dieu. The journey, including transfers, takes approximately 7 h.

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The distance between Mannheim and Grenoble is 523 km. The road distance is 648.6 km.

Get driving directions

The best way to get from Mannheim to Grenoble without a car is to train which takes 7 h and costs 120€ - 150€.

More details

It takes approximately 7 h to get from Mannheim to Grenoble, including transfers.

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Mannheim to Grenoble train services, operated by TGV, depart from Mannheim Hbf station.

More details

The quickest flight from Frankfurt Airport to Lyon Airport is the direct flight which takes 1 h 15 min.

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Map of how to get from Mannheim to Grenoble.
Launch map view
  • Distance: 326.7 miles
  • Duration: 7 h

What companies run services between Mannheim, Germany and Grenoble, France?

You can take a train from Mannheim to Grenoble via Lyon Part Dieu in around 7 h.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Lyon
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$120 - $390
Flights from Frankfurt to Lyon via Munich
Ave. Duration
3 h
When
Every day
Estimated price
$120 - $390
Flights from Frankfurt to Geneva
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$140 - $600
Flights from Frankfurt to Geneva via Zurich
Ave. Duration
2 h 48 min
When
Every day
Estimated price
$140 - $600
Flights from Stuttgart to Lyon via Frankfurt
Ave. Duration
3 h 17 min
When
Every day
Estimated price
$190 - $950
Flights from Frankfurt to Turin
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$170 - $800
Flights from Frankfurt to Turin via Munich
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$170 - $700
Swiss
Website
swiss.com
Flights from Frankfurt to Geneva
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$140 - $600
Flights from Frankfurt to Geneva via Zurich
Ave. Duration
2 h 48 min
When
Every day
Estimated price
$140 - $600
Luxair
Website
luxair.lu
Flights from Frankfurt to Turin
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$170 - $800
Flights from Frankfurt to Turin via Luxembourg
Ave. Duration
3 h
When
Thursday and Friday
Estimated price
$1,700 - $3,400
Air France
Website
airfrance.com
Flights from Strasbourg to Lyon
Ave. Duration
1 h
When
Every day
Estimated price
$95 - $550
Flights from Stuttgart to Lyon via Paris CDG
Ave. Duration
3 h 20 min
When
Monday to Saturday
Estimated price
$150 - $550
Hop!
Website
hop.com
Flights from Strasbourg to Lyon
Ave. Duration
1 h
When
Every day
Estimated price
$95 - $550
Brussels Airlines
Website
brusselsairlines.com
Flights from Frankfurt to Lyon via Brussels
Ave. Duration
3 h 25 min
When
Every day
Estimated price
$120 - $370
Twin Jet
Website
twinjet.fr
Flights from Stuttgart to Lyon
Ave. Duration
1 h 20 min
When
Monday to Friday
Estimated price
$150 - $650
Train operators
TGV
Phone
0033 892 353535
Website
sncf.com
Train from Mannheim Hbf to Lyon Part Dieu
Ave. Duration
5 h 17 min
Frequency
Twice a week
Estimated price
$120 - $140
Website
en.oui.sncf
2nd Class
$120 - $140
1st Class
$160 - $240
Train from Mannheim Hbf to Karlsruhe Hbf
Ave. Duration
25 min
Frequency
Twice daily
Estimated price
$17 - $22
Website
en.oui.sncf
2nd Class
$17 - $22
1st Class
$30 - $35
Train from Lyon-St Exupery(TGV) to Grenoble
Ave. Duration
1 h 3 min
Frequency
Every 2 hours
Estimated price
$27 - $33
Website
en.oui.sncf
2nd Class
$27 - $33
1st Class
$46 - $50
Train from Torino Porta Susa to Chambery-Challes-E
Ave. Duration
2 h 39 min
Frequency
3 times a day
Estimated price
$40 - $50
Website
en.oui.sncf
2nd Class
$40 - $50
1st Class
$65 - $80
SNCF
Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Lyon Part Dieu to Grenoble
Ave. Duration
1 h 24 min
Frequency
Every 30 minutes
Estimated price
$24 - $35
Website
en.oui.sncf
2nd Class
$24 - $35
1st Class
$30 - $50
Train from Chambery-Challes-E to Grenoble
Ave. Duration
47 min
Frequency
Hourly
Estimated price
$16 - $24
Website
en.oui.sncf
2nd Class
$16 - $24
1st Class
$21 - $35
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Mannheim Hbf to Basel SBB
Ave. Duration
2 h 11 min
Frequency
Hourly
Estimated price
$45 - $80
Website
bahn.de
Standard
$45 - $80
First
$55 - $130
Train from Mannheim Hbf to Karlsruhe Hbf
Ave. Duration
22 min
Frequency
Hourly
Estimated price
$19 - $28
Website
bahn.de
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
30 min
Frequency
Hourly
Estimated price
$21 - $25
Website
bahn.de
Second Class
$21 - $25
Train from Mannheim Hbf to Offenburg
Ave. Duration
56 min
Frequency
Hourly
Estimated price
$30 - $50
Website
bahn.de
Train from Mannheim Hbf to Stuttgart Hbf
Ave. Duration
38 min
Frequency
Hourly
Estimated price
$28 - $40
Website
bahn.de
Trenitalia Eurocity
Phone
+39 06 68475475
Website
trenitalia.com
Train from Mannheim Hbf to Basel Sbb
Ave. Duration
2 h 8 min
Frequency
Once daily
Estimated price
$45 - $80
Website
orario.trenitalia.com
Standard
$45 - $80
First
$55 - $130
Swiss Railways (SBB/CFF/FFS)
Website
sbb.ch
Train from Basel SBB to Biel/Bienne
Ave. Duration
1 h 7 min
Frequency
Hourly
Estimated price
$29 - $55
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Biel/Bienne to Genève
Ave. Duration
1 h 29 min
Frequency
Hourly
Estimated price
$40 - $80
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Genève to Grenoble
Ave. Duration
2 h 13 min
Frequency
Every 4 hours
Estimated price
$25 - $40
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Bus operators
FlixBus
Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Karlsruhe to Grenoble
Ave. Duration
11 h 15 min
Frequency
4 times a week
Estimated price
$35 - $65
Website
flixbus.co.uk

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