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  • Deutsche Bahn
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  • SNCF
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There are 10 ways to get from Mannheim to Grenoble by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train inOui TGV  •  7 h

  1. Take the train from Mannheim Hbf to Lyon Part Dieu Tgv
  2. Take the train from Lyon Part Dieu to Grenoble

$148 - $170

Cheapest option

Train, bus  •  12 h 37 min

  1. Take the train from Mannheim Hbf to Karlsruhe Hbf Ice / ...
  2. Take the bus from Karlsruhe to Grenoble 720

$52 - $93

8 alternative options

Train via Bern  •  8 h 47 min

  1. Take the train from Mannheim Hbf to Basel SBB Ice / ...
  2. Take the train from Basel SBB to Bern Ice / ...
  3. Take the train from Bern to Genève 1 / ...
  4. Take the train from Genève to Grenoble

$144 - $280

Bus  •  11 h 44 min

  1. Take the bus from Mannheim to Lyon
  2. Take the bus from Lyon, Lyon Perrache to Grenoble 709 / ...

$87 - $125

Drive  •  6 h 7 min

  1. Drive from Mannheim to Grenoble 405.4 miles

$85 - $130

Train to Frankfurt, fly to Lyon, train  •  5 h 46 min

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Lyon (LYS) FRA - LYS
  3. Take the train from Lyon-St Exupery(TGV) to Grenoble

$114 - $324

Train to Frankfurt, fly to Geneva, train  •  7 h 14 min

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Geneva (GVA) FRA - GVA
  3. Take the train from Genève to Grenoble

$132 - $354

Train to Stuttgart, fly to Lyon, train  •  6 h 35 min

  1. Take the train from Mannheim Hbf to Stuttgart Hbf
  2. Fly from Stuttgart (STR) to Lyon (LYS) STR - LYS
  3. Take the train from Lyon-St Exupery(TGV) to Grenoble

$137 - $359

Train, train to Strasbourg, fly to Lyon  •  6 h 31 min

  1. Take the train from Mannheim Hbf to Karlsruhe Hbf
  2. Take the train from Karlsruhe Hbf to Strasbourg
  3. Fly from Strasbourg (SXB) to Lyon (LYS) SXB - LYS
  4. Take the train from Lyon-St Exupery(TGV) to Grenoble

$123 - $470

Train to Frankfurt, fly to Turin, train  •  9 h 15 min

  1. Take the train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
  2. Fly from Frankfurt (FRA) to Turin (TRN) FRA - TRN
  3. Take the train from Torino Porta Susa to Chambery-Challes-E
  4. Take the train from Chambery-Challes-E to Grenoble

$165 - $424

Questions & Answers

The cheapest way to get from Mannheim to Grenoble is to train and bus which costs 45€ - 85€ and takes 12 h 37 min.

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The quickest way to get from Mannheim to Grenoble is to train and fly which costs 95€ - 290€ and takes 5 h 46 min.

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No, there is no direct bus from Mannheim to Grenoble. However, there are services departing from Mannheim and arriving at Grenoble via Lyon, Lyon Perrache. The journey, including transfers, takes approximately 11 h 44 min.

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No, there is no direct train from Mannheim to Grenoble. However, there are services departing from Mannheim Hbf and arriving at Grenoble via Lyon Part Dieu. The journey, including transfers, takes approximately 7 h.

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The distance between Mannheim and Grenoble is 523 km. The road distance is 648.6 km.

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The best way to get from Mannheim to Grenoble without a car is to train which takes 7 h and costs 120€ - 150€.

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It takes approximately 7 h to get from Mannheim to Grenoble, including transfers.

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Mannheim to Grenoble bus services, operated by Eurolines FR, depart from Mannheim station.

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Mannheim to Grenoble train services, operated by inOui TGV, depart from Mannheim Hbf station.

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The best way to get from Mannheim to Grenoble is to train which takes 7 h and costs 120€ - 150€. Alternatively, you can bus, which costs 75€ - 110€ and takes 11 h 44 min.

Mode details

Map of how to get from Mannheim to Grenoble.
Launch map view
  • Distance: 326.7 miles
  • Duration: 7 h

What companies run services between Mannheim, Germany and Grenoble, France?

You can take a train from Mannheim to Grenoble via Lyon Part Dieu in around 7 h. Alternatively, you can take a bus from Mannheim to Grenoble via Lyon and Lyon, Lyon Perrache in around 11 h 44 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Lyon
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$120 - $390
Flights from Frankfurt to Lyon via Munich
Ave. Duration
3 h 15 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $390
Flights from Frankfurt to Geneva
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$140 - $600
Flights from Frankfurt to Geneva via Munich
Ave. Duration
3 h 10 min
When
Every day
Estimated price
$140 - $600
Flights from Frankfurt to Geneva via Zurich
Ave. Duration
3 h 5 min
When
Every day
Estimated price
$140 - $600
Flights from Stuttgart to Lyon via Frankfurt
Ave. Duration
3 h 32 min
When
Every day
Estimated price
$190 - $950
Flights from Frankfurt to Turin
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$170 - $800
Flights from Frankfurt to Turin via Munich
Ave. Duration
3 h 18 min
When
Every day
Estimated price
$170 - $650
Swiss
Website
swiss.com
Flights from Frankfurt to Geneva
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$140 - $600
Flights from Frankfurt to Geneva via Zurich
Ave. Duration
3 h 5 min
When
Every day
Estimated price
$140 - $600
Air France
Website
airfrance.com
Flights from Frankfurt to Lyon via Paris CDG
Ave. Duration
3 h 25 min
When
Every day
Estimated price
$140 - $430
Flights from Strasbourg to Lyon
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$95 - $550
Luxair
Website
luxair.lu
Flights from Frankfurt to Turin
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$170 - $800
Flights from Frankfurt to Turin via Luxembourg
Ave. Duration
3 h 5 min
When
Friday
Estimated price
$1,700 - $3,400
Hop!
Website
hop.com
Flights from Strasbourg to Lyon
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$95 - $550
Twin Jet
Website
twinjet.fr
Flights from Stuttgart to Lyon
Ave. Duration
1 h 20 min
When
Monday to Friday
Estimated price
$150 - $650
Train operators
inOui TGV
Phone
0033 892 353535
Website
en.oui.sncf
Train from Mannheim Hbf to Lyon Part Dieu
Ave. Duration
5 h 17 min
Frequency
Once daily
Estimated price
$120 - $140
Website
en.oui.sncf
2nd Class
$120 - $140
1st Class
$160 - $240
Train from Mannheim Hbf to Karlsruhe Hbf
Ave. Duration
25 min
Frequency
3 times a day
Estimated price
$17 - $22
Website
en.oui.sncf
2nd Class
$17 - $22
1st Class
$30 - $35
Train from Lyon-St Exupery(TGV) to Grenoble
Ave. Duration
1 h 3 min
Frequency
Every 2 hours
Estimated price
$27 - $33
Website
en.oui.sncf
2nd Class
$27 - $33
1st Class
$46 - $50
Train from Karlsruhe Hbf to Strasbourg
Ave. Duration
41 min
Frequency
Every 4 hours
Estimated price
$20 - $26
Website
en.oui.sncf
2nd Class
$20 - $26
1st Class
$37 - $39
Train from Torino Porta Susa to Chambery-Challes-E
Ave. Duration
2 h 39 min
Frequency
3 times a day
Estimated price
$40 - $50
Website
en.oui.sncf
2nd Class
$40 - $50
1st Class
$65 - $80
SNCF

Loosely translated as the French National Railway Corporation, the SNCF is France’s state-owned railway company. It covers the country’s extensive rail network, as well as the TGV and Thalys, France’s two high-speed railway networks. With over 14,000 trains operating daily, it is a fast and efficient way of travelling around the country. The railway network consists of about 32,000km in total, of which 1800km are high-speed lines and 14,500km are electrified.

Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Lyon Part Dieu to Grenoble
Ave. Duration
1 h 24 min
Frequency
Every 30 minutes
Estimated price
$24 - $35
Website
en.oui.sncf
2nd Class
$24 - $35
1st Class
$30 - $50
Train from Chambery-Challes-E to Grenoble
Ave. Duration
47 min
Frequency
Every 30 minutes
Estimated price
$16 - $24
Website
en.oui.sncf
2nd Class
$16 - $24
1st Class
$21 - $35
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Mannheim Hbf to Basel SBB
Ave. Duration
2 h 11 min
Frequency
Hourly
Estimated price
$60 - $95
Website
bahn.de
Train from Mannheim Hbf to Karlsruhe Hbf
Ave. Duration
22 min
Frequency
Every 30 minutes
Estimated price
$19 - $28
Website
bahn.de
Train from Mannheim Hbf to Frankfurt(M) Flughafen Fernbf
Ave. Duration
30 min
Frequency
Every 30 minutes
Estimated price
$21 - $35
Website
bahn.de
Train from Mannheim Hbf to Stuttgart Hbf
Ave. Duration
37 min
Frequency
Every 30 minutes
Estimated price
$28 - $40
Website
bahn.de
Train from Karlsruhe Hbf to Strasbourg
Ave. Duration
41 min
Frequency
4 times a day
Estimated price
$23 - $35
Website
bahn.de
Trenitalia Eurocity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Mannheim Hbf to Basel Sbb
Ave. Duration
2 h 8 min
Frequency
Once daily
Estimated price
$40 - $65
Website
orario.trenitalia.com
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs. Swiss Railways codeshares with American Airlines and Swiss International Air Lines out of Zurich International Airport.

Contact Details
Website
sbb.ch
Train from Basel SBB to Bern
Ave. Duration
59 min
Frequency
Every 30 minutes
Estimated price
$35 - $65
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Bern to Genève
Ave. Duration
1 h 44 min
Frequency
Hourly
Estimated price
$40 - $80
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Genève to Grenoble
Ave. Duration
2 h 15 min
Frequency
Every 4 hours
Estimated price
$25 - $40
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Bus operators
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Mannheim to Lyon
Ave. Duration
9 h 28 min
Frequency
3 times a week
Estimated price
$80 - $120
Schedules at
eurolines.fr
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Lyon, Lyon Perrache to Grenoble
Ave. Duration
1 h 30 min
Frequency
Every 4 hours
Estimated price
$5 - $10
Website
flixbus.co.uk
Bus from Karlsruhe to Grenoble
Ave. Duration
11 h 15 min
Frequency
3 times a week
Estimated price
$35 - $65
Website
flixbus.co.uk
Ouibus

As the bus subsidiary of French railway SNCF, Ouibus offers comfortable, eco-friendly coaches serving 35 French cities and 11 European cities at affordable fares. Ouibus journeys are safe and comfortable, with the four-star coaches offering power outlets, restrooms and WiFi. All Ouibus stations are located close to town centres for easy access to public transport. Getting on one of the 130 daily journeys is easy - electronic travel documents include your ticket and a personalised mini-guide with handy information.

Contact Details
Phone
0890715298
Website
ouibus.com
Bus from Lyon Gare Perrache to Grenoble - Bus station
Ave. Duration
1 h 30 min
Frequency
5 times a day
Estimated price
$4 - $6
Website
Ouibus
Isilines
Phone
0 892 89 12 00
Website
isilines.com
Bus from Lyon to Grenoble
Ave. Duration
1 h 50 min
Frequency
Twice daily
Estimated price
$5 - $10
Schedules at
isilines.com

Want to know more about travelling around France

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Frankfurt Airport to Lyon Airport is the direct flight which takes 1 h 15 min.

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Mannheim to Grenoble bus services, operated by FlixBus, arrive at Grenoble station.

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Mannheim to Grenoble train services, operated by SNCF, arrive at Grenoble station.

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Yes, the driving distance between Mannheim to Grenoble is 649 km. It takes approximately 6 h 7 min to drive from Mannheim to Grenoble.

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Air France and Lufthansa offer flights from Frankfurt Airport to Lyon Airport.

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Book your Mannheim to Grenoble train tickets online with Loco2 and Loco2.

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There are 422+ hotels available in Grenoble. Prices start at $56 USD per night.

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