There are 5 ways to get from Manlius to St. Louis by plane, train (Amtrak), bus (Greyhound), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Syracuse Hancock International Airport (SYR) to Lambert–St. Louis International Airport (STL)SYR - STL
5h 57m$296–1,212Bus
cheapest- Take the bus from Syracuse Bus Station to Scranton Bus Station
- Take the bus from Scranton, PA to Harrisburg, PA
- Take the bus from Harrisburg Bus Station to St Louis Bus Station
28h 9m$149–441Train (Amtrak)
- Take the train from Syracuse Regional Transportation Center to Chicago Union StationLake Shore Limited
- Take the train from Chicago Union Station to St. LouisLincoln Service / ...
19h 14m$232–675Drive 891.9 mi
- Drive from Manlius to St. Louis891.9 mi
15h 6m$163–236Train, bus
- Take the train from Syracuse Regional Transportation Center to Chicago Union StationLake Shore Limited
- Take the bus from Chicago Bus Station to St Louis Bus StationFlixBus N2521 / ...
22h 40m$162–346
Manlius to St. Louis by bus
Questions & Answers
The cheapest way to get from Manlius to St. Louis is to drive which costs $160 - $240 and takes 15h 6m.
The fastest way to get from Manlius to St. Louis is to fly which takes 5h 57m and costs $290 - $1,300.
No, there is no direct bus from Manlius to St. Louis station. However, there are services departing from Fayette St & Pleasant St and arriving at St Louis Bus Station via B8, Syracuse Bus Station, Scranton, PA and Harrisburg Bus Station. The journey, including transfers, takes approximately 28h 9m.
The distance between Manlius and St. Louis is 836 miles. The road distance is 897.1 miles.
The best way to get from Manlius to St. Louis without a car is to train which takes 19h 14m and costs $230 - $700.
It takes approximately 5h 57m to get from Manlius to St. Louis, including transfers.
Manlius to St. Louis bus services, operated by Greyhound USA, depart from Syracuse Bus Station.
The best way to get from Manlius to St. Louis is to fly which takes 5h 57m and costs $290 - $1,300. Alternatively, you can train, which costs $230 - $700 and takes 19h 14m, you could also bus, which costs $140 - $450 and takes 28h 9m.
Manlius to St. Louis bus services, operated by Greyhound USA, arrive at Scranton Bus Station.
St. Louis is 1h behind Manlius. It is currently 8:19 AM in Manlius and 7:19 AM in St. Louis.
What companies run services between Manlius, NY, USA and St. Louis, MO, USA?
Delta, American Airlines, and United Airlines fly from Syracuse Hancock International Airport (SYR) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a vehicle from Manlius to St. Louis via Syracuse Regional Transportation Center and Chicago Union Station in around 19h 14m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Syracuse Hancock International Airport to Lambert–St. Louis International Airport via Philadelphia
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Syracuse Hancock International Airport to Lambert–St. Louis International Airport via Reagan Washington
- Ave. Duration
- 5h 34m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $230–1,200
- Website
- united.com
Flights from Syracuse Hancock International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Syracuse Hancock International Airport to Lambert–St. Louis International Airport via Washington Dulles
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $230–1,200
- Website
- delta.com
Flights from Syracuse Hancock International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $200–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Syracuse Regional Transportation Center to Chicago Union Station
- Ave. Duration
- 13h 7m
- Frequency
- Twice daily
- Estimated price
- $120–230
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $40–360
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Syracuse Bus Station to Scranton Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $27–50
- Website
- https://www.greyhound.com/
Bus from Harrisburg Bus Station to St Louis Bus Station
- Ave. Duration
- 18h 5m
- Frequency
- Twice daily
- Estimated price
- $100–300
- Website
- https://www.greyhound.com/
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Scranton, PA to Harrisburg, PA
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $20–65
- Website
- https://www.ourbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Scranton, PA to Harrisburg, PA
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $24–75
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $24–70
- Flexible
- $45–75
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- 3 times a day
- Estimated price
- $40–100
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Yes, the driving distance between Manlius to St. Louis is 897 miles. It takes approximately 15h 6m to drive from Manlius to St. Louis.
There are 397+ hotels available in St. Louis.