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How to get fromManlius to St. Louisby plane, train (Amtrak), bus (Greyhound), car, train or bus

Find Transport to St. Louis

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There are 5 ways to get from Manlius to St. Louis by plane, train (Amtrak), bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Syracuse Hancock International Airport (SYR) to Lambert–St. Louis International Airport (STL)planeSYR - STL
    5h 57m
    $296–1,212
  2. Bus

    cheapest
    1. Take the bus from Syracuse Bus Station to Scranton Bus Stationbus
    2. Take the bus from Scranton, PA to Harrisburg, PAbus
    3. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus
    28h 9m
    $149–441
  3. Train (Amtrak)

    1. Take the train from Syracuse Regional Transportation Center to Chicago Union StationtrainLake Shore Limited
    2. Take the train from Chicago Union Station to St. LouistrainLincoln Service / ...
    19h 14m
    $232–675
  4. Drive 891.9 mi

    1. Drive from Manlius to St. Louiscar891.9 mi
    15h 6m
    $163–236
  5. Train, bus

    1. Take the train from Syracuse Regional Transportation Center to Chicago Union StationtrainLake Shore Limited
    2. Take the bus from Chicago Bus Station to St Louis Bus StationbusFlixBus N2521 / ...
    22h 40m
    $162–346

Manlius to St. Louis by bus

Calendar7Weekly Buses
Duration28h 9mAverage Duration
Ticket$149Cheapest Price
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Questions & Answers

What companies run services between Manlius, NY, USA and St. Louis, MO, USA?

Delta, American Airlines, and United Airlines fly from Syracuse Hancock International Airport (SYR) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a vehicle from Manlius to St. Louis via Syracuse Regional Transportation Center and Chicago Union Station in around 19h 14m.

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