There are 5 ways to get from Manlius to Pittsburgh by plane, train (Amtrak), bus (Greyhound), car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Syracuse Hancock International Airport (SYR) to Pittsburgh International Airport (PIT)plane SYR - PIT
5h 27m$453–759Drive 327.9 mi
cheapest- Drive from Manlius to Pittsburghcar 327.9 mi
7h 56m$60–87Train (Amtrak)
- Take the train from Syracuse Regional Transportation Center to Cleveland Amtraktrain Lake Shore Limited
- Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain Floridian
10h 18m$217–391Bus (Greyhound)
- Take the bus from Syracuse Bus Station to Cleveland Bus Stationbus Greyhound US0171
- Take the bus from Cleveland Bus Station to Pittsburgh Intermodal Stationbus Greyhound US0420 / ...
12h 4m$72–156Bus via Buffalo
- Take the bus from Syracuse to Buffalobus Adt N804 / ...
- Take the bus from Buffalo to Pittsburghbus Fab530
13h 37m$134–261
Manlius to Pittsburgh by bus (Greyhound)
Questions & Answers
The cheapest way to get from Manlius to Pittsburgh is to drive which costs $60 - $90 and takes 7h 56m.
The fastest way to get from Manlius to Pittsburgh is to fly which takes 5h 27m and costs $450 - $800.
No, there is no direct bus from Manlius to Pittsburgh station. However, there are services departing from Fayette St & Pleasant St and arriving at Pittsburgh Intermodal Station via B8, Syracuse Bus Station and Cleveland Bus Station. The journey, including transfers, takes approximately 12h 4m.
No, there is no direct train from Manlius to Pittsburgh station. However, there are services departing from Syracuse Regional Transportation Center and arriving at Pittsburgh Amtrak Station via Cleveland Amtrak. The journey, including transfers, takes approximately 10h 18m.
The distance between Manlius and Pittsburgh is 323 miles. The road distance is 329.8 miles.
The best way to get from Manlius to Pittsburgh without a car is to train which takes 10h 18m and costs $210 - $400.
It takes approximately 5h 27m to get from Manlius to Pittsburgh, including transfers.
Manlius to Pittsburgh bus services, operated by Greyhound USA, depart from Syracuse Bus Station.
Manlius to Pittsburgh train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.
The best way to get from Manlius to Pittsburgh is to fly which takes 5h 27m and costs $450 - $800. Alternatively, you can train, which costs $210 - $400 and takes 10h 18m, you could also bus, which costs $70 - $160 and takes 12h 4m.
What companies run services between Manlius, NY, USA and Pittsburgh, PA, USA?
United Airlines, Delta, and American Airlines fly from Syracuse Hancock International Airport (SYR) to Pittsburgh International Airport (PIT) hourly. Alternatively, you can take a vehicle from Manlius to Pittsburgh Amtrak Station via Syracuse Regional Transportation Center and Cleveland Amtrak in around 10h 18m.
- Website
- delta.com
Flights from Syracuse Hancock International Airport to Pittsburgh International Airport via New York La Guardia
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $90–550
Flights from Syracuse Hancock International Airport to Pittsburgh International Airport via New York JFK
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $90–550
Flights from Syracuse Hancock International Airport to Pittsburgh International Airport via Detroit
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $90–550
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $85–500
Flights from Syracuse Hancock International Airport to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 4h 56m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–500
- Website
- united.com
Flights from Syracuse Hancock International Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $80–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Syracuse Regional Transportation Center to Cleveland Amtrak
- Ave. Duration
- 5h 48m
- Frequency
- Twice daily
- Estimated price
- $100–210
- Website
- https://www.amtrak.com/home.html
Train from Cleveland Amtrak to Pittsburgh Amtrak Station
- Ave. Duration
- 3h 11m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Syracuse Bus Station to Cleveland Bus Station
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 2h 5m
- Frequency
- 4 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Syracuse to Buffalo
- Ave. Duration
- 3h
- Frequency
- 5 times a day
- Estimated price
- $24–45
- Website
- https://www.greyhound.com/
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Syracuse to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- Every 4 hours
- Estimated price
- $28–100
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–95
- Flexible
- $55–100
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Syracuse to Buffalo
- Ave. Duration
- 3h 30m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Schedules at
- flixbus.com
- Phone
- +1 814-574-1827
- Website
- fullingtontours.com
Bus from Buffalo to Pittsburgh
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $110–200
- Website
- https://www.fullingtontours.com
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More Questions & Answers
Manlius to Pittsburgh bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Manlius to Pittsburgh train services, operated by Amtrak, arrive at Cleveland Amtrak station.
Yes, the driving distance between Manlius to Pittsburgh is 330 miles. It takes approximately 7h 56m to drive from Manlius to Pittsburgh.
There are 328+ hotels available in Pittsburgh.








