There are 4 ways to get from Manlius to Buffalo by train (Amtrak), bus (Flixbus, Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Syracuse Regional Transportation Center to BuffaloEmpire Service / ...
3h 17m$99–175Bus
cheapest- Take the bus from Syracuse Bus Station to BuffaloFlixBus 2686 / ...
4h 58m$28–61Drive 159.3 mi
- Drive from Manlius to Buffalo159.3 mi
2h 52m$30–42Fly
- Fly from Syracuse Hancock International Airport (SYR) to Buffalo Niagara International Airport (BUF)SYR - BUF
5h 32m$367–1,789
Manlius to Buffalo by bus
Questions & Answers
The cheapest way to get from Manlius to Buffalo is to drive which costs $29 - $45 and takes 2h 52m.
The fastest way to get from Manlius to Buffalo is to drive which takes 2h 52m and costs $29 - $45.
No, there is no direct bus from Manlius to Buffalo. However, there are services departing from Fayette St & Pleasant St and arriving at Buffalo via B8 and Syracuse Bus Station. The journey, including transfers, takes approximately 4h 58m.
The distance between Manlius and Buffalo is 161 miles. The road distance is 160.3 miles.
The best way to get from Manlius to Buffalo without a car is to train which takes 3h 17m and costs $95 - $180.
It takes approximately 3h 17m to get from Manlius to Buffalo, including transfers.
Manlius to Buffalo bus services, operated by Flixbus USA, depart from Syracuse Bus Station.
The best way to get from Manlius to Buffalo is to train which takes 3h 17m and costs $95 - $180. Alternatively, you can bus, which costs $28 - $65 and takes 4h 58m, you could also fly, which costs $360 - $1,800 and takes 5h 32m.
Manlius to Buffalo bus services, operated by Flixbus USA, arrive at Buffalo station.
Yes, the driving distance between Manlius to Buffalo is 160 miles. It takes approximately 2h 52m to drive from Manlius to Buffalo.
What companies run services between Manlius, NY, USA and Buffalo, NY, USA?
Amtrak operates a train from Syracuse Regional Transportation Center to Buffalo 3 times a day. Tickets cost $29–45 and the journey takes 2h 56m. VIA Rail also services this route once daily. Alternatively, Flixbus USA operates a bus from Syracuse Bus Station to Buffalo every 4 hours. Tickets cost $26–40 and the journey takes 2h 55m. Two other operators also service this route.
- Website
- delta.com
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $270–1,600
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $310–1,700
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 7h 1m
- When
- Every day
- Estimated price
- $280–1,600
- Website
- united.com
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $300–1,700
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 6h 3m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $270–1,600
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 5h 1m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $300–1,700
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $280–1,600
- Website
- jetblue.com
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Boston
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $320–1,700
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $280–1,600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Syracuse Regional Transportation Center to Buffalo
- Ave. Duration
- 2h 56m
- Frequency
- 3 times a day
- Estimated price
- $29–45
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from Syracuse Regional Transportation Center to Buffalo
- Ave. Duration
- 2h 41m
- Frequency
- Once daily
- Estimated price
- $27–90
- Website
- https://www.viarail.ca/en
- Economy Adult - same day booking
- $30–90
- Economy Adult - Advanced Booking
- $30–70
- Economy Escape Advanced Booking - Adult
- $27–40
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $26–40
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- $26–40
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $27–45
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 230+ hotels available in Buffalo.