Rome2Rio

How to get fromManitowoc to St. Louisby bus, train, bus (Greyhound, Flixbus), car, taxi, or plane

Find Transport to St. Louis

See all options

There are 8 ways to get from Manitowoc to St. Louis by bus, train, bus (Greyhound, Flixbus), car, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Manitowoc to Milwaukee Intermodal Stationbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    9h 59m
    $216–359

  2. Bus

    cheapest
    1. Take the bus from Manitowoc to Milwaukee Intermodal Stationbus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    11h 14m
    $79–142

  3. Drive  450.7 mi

    1. Drive from Manitowoc to St. Louiscar car 450.7 mi
    7h 36m
    $83–119

  4. Taxi to Appleton International Airport, fly

    1. Take the taxi from Manitowoc to Appleton International Airport (ATW)taxi taxi
    2. Fly from Appleton International Airport (ATW) to Lambert–St. Louis International Airport (STL)plane plane ATW - STL
    5h 59m
    $185–585

  5. Bus, train via Bloomington

    1. Take the bus from Manitowoc to Milwaukee Intermodal Stationbus bus
    2. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    3. Take the bus from Multi-Modal Facility to Uptown Stationbus bus
    4. Take the train from Bloomington-Normal to St. Louistrain train
    13h 3m
    $192–294

  6. Bus to General Mitchell International Airport, fly

    1. Take the bus from Manitowoc to Milwaukee Intermodal Stationbus bus
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    5h 16m
    $506–911

  7. Bus to Green Bay, fly

    1. Take the bus from Manitowoc to Green Bay Transit Centerbus bus
    2. Fly from Green Bay (GRB) to Lambert–St. Louis International Airport (STL)plane plane GRB - STL
    6h 34m
    $123–529

  8. Bus, bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Manitowoc to Milwaukee Intermodal Stationbus bus
    2. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    3. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    7h 21m
    $332–789

Appleton International Airport (ATW) to Lambert–St. Louis International Airport (STL) flights

Calendar97Weekly Planes
Duration5h 14mAverage Duration
Ticket$73Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Manitowoc to St. Louis.ExpandLaunch map view
  • Distance: 448.4 mi
  • Duration: 9h 59m

What companies run services between Manitowoc, WI, USA and St. Louis, MO, USA?

You can take a vehicle from Manitowoc to St Louis Bus Station via Manitowoc, Milwaukee Intermodal Station, and Chicago Bus Station in around 11h 14m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There