There are 8 ways to get from Manitowoc to Louisville by taxi, plane, bus (Amtrak, Flixbus), bus, train, car, or bus (Greyhound, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Appleton International Airport, fly
best- Take the taxi from Manitowoc to Appleton International Airport (ATW)
- Fly from Appleton International Airport (ATW) to Louisville International Airport (SDF)ATW - SDF
6h 15m$192–581Drive 461.9 mi
cheapest- Drive from Manitowoc to Louisville461.9 mi
7h 57m$85–122Bus
- Take the bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Take the bus from Milwaukee Intermodal Station to Indianapolis
- Take the bus from Indianapolis Union Station to Louisville, KY
12h 33m$88–214Bus, train
- Take the bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Take the train from Milwaukee to Chicago Union Station
- Take the train from Chicago Union Station to Indianapolis
- Take the bus from Indianapolis Union Station to Louisville, KY
13h 31m$96–214Bus to Green Bay, fly
- Take the bus from Manitowoc, WI to Green Bay, WI
- Fly from Green Bay (GRB) to Louisville International Airport (SDF)GRB - SDF
6h 58m$126–530Bus to General Mitchell International Airport, fly
- Take the bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)MKE - SDF
7h 58m$124–842Bus, bus to Chicago O'Hare International Airport, fly
- Take the bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)ORD - SDF
8h 11m$177–590Bus via Chicago
- Take the bus from Manitowoc, WI to Milwaukee103
- Take the bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departures
- Take the bus from Chicago Bus Station to Indianapolis Union Station
- Take the bus from Indianapolis Union Station to Louisville, KY
13h 24m$120–234
Appleton International Airport (ATW) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Manitowoc to Louisville is to drive which costs $80 - $130 and takes 7h 57m.
The fastest way to get from Manitowoc to Louisville is to taxi and fly which takes 6h 15m and costs $190 - $600.
The distance between Manitowoc and Louisville is 502 miles. The road distance is 464.6 miles.
The best way to get from Manitowoc to Louisville without a car is to bus which takes 12h 33m and costs $85 - $220.
It takes approximately 6h 15m to get from Manitowoc to Louisville, including transfers.
Louisville is 1h ahead of Manitowoc. It is currently 8:36 AM in Manitowoc and 9:36 AM in Louisville.
Yes, the driving distance between Manitowoc to Louisville is 465 miles. It takes approximately 7h 57m to drive from Manitowoc to Louisville.
There are 499+ hotels available in Louisville.
What companies run services between Manitowoc, WI, USA and Louisville, KY, USA?
You can take a vehicle from Manitowoc to Louisville, KY via Manitowoc Amtrak Bus Stop, Milwaukee, Milwaukee Intermodal Station, Indianapolis, and Indianapolis Union Station in around 12h 33m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- united.com
Flights from Appleton International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $75–440
Flights from Green Bay to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $75–450
Flights from General Mitchell International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $100–700
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $55–370
- Website
- aa.com
Flights from Appleton International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $75–440
Flights from Appleton International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 25m
- When
- Tuesday
- Estimated price
- $120–600
Flights from Appleton International Airport to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 29m
- When
- Wednesday and Friday
- Estimated price
- $160–750
Flights from Green Bay to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $75–450
Flights from General Mitchell International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 6m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $100–700
Flights from General Mitchell International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 50m
- When
- Tuesday
- Estimated price
- $180–950
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $55–370
- Website
- delta.com
Flights from Appleton International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $85–480
Flights from Appleton International Airport to Louisville International Airport via Minneapolis
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $100–550
Flights from Appleton International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 7h 41m
- When
- Every day
- Estimated price
- $120–600
Flights from Green Bay to Louisville International Airport via Minneapolis
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $100–550
Flights from Green Bay to Louisville International Airport via Detroit
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $85–480
Flights from Green Bay to Louisville International Airport via Atlanta
- Ave. Duration
- 7h 49m
- When
- Every day
- Estimated price
- $120–600
Flights from General Mitchell International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 39m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $180–950
Flights from General Mitchell International Airport to Louisville International Airport via Minneapolis
- Ave. Duration
- 4h 49m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $170–900
Flights from General Mitchell International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $130–750
Flights from Chicago O'Hare International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $70–420
- Website
- southwest.com
Flights from General Mitchell International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 42m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $140–800
Flights from General Mitchell International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 33m
- When
- Monday, Saturday, and Sunday
- Estimated price
- $200–1,000
Flights from General Mitchell International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 4h 55m
- When
- Monday and Friday
- Estimated price
- $100–700
Flights from Chicago O'Hare International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Monday to Wednesday
- Estimated price
- $75–430
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $23–40
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–70
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
Bus from Manitowoc, WI to Green Bay, WI
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 989-725-5105
- Website
- indiantrails.com
Bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $14–35
- Website
- https://indiantrails.com
Bus from Manitowoc, WI to Green Bay, WI
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $7–23
- Website
- https://indiantrails.com
- Phone
- +1 800-236-1240
- Website
- golamers.com
Bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Ave. Duration
- 2h
- Frequency
- Twice a week
- Estimated price
- $21–50
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
Bus from Manitowoc, WI to Green Bay, WI
- Ave. Duration
- 55 min
- Frequency
- Twice a week
- Estimated price
- $14–23
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
Bus from Manitowoc, WI to Milwaukee
- Ave. Duration
- 2h 30m
- Frequency
- Twice a week
- Estimated price
- $22–60
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Milwaukee Intermodal Station to Indianapolis
- Ave. Duration
- 6h 10m
- Frequency
- 6 times a week
- Estimated price
- $45–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- $35–38
- Schedules at
- coachusa.com
Bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 30m
- Frequency
- Every 2 hours
- Estimated price
- $32–35
- Schedules at
- coachusa.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Indianapolis Union Station
- Ave. Duration
- 3h 5m
- Frequency
- Every 4 hours
- Estimated price
- $35–80
- Website
- https://www.greyhound.com/
- Ave. Duration
- 1h 15m
- Estimated price
- $110–140
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide












